Mohs in cSCC: smaller defects, no significant recurrence gap

Editor's Pick: Five-year Recurrence Rate of Cutaneous Squamous Cell Carcinoma After Mohs Micrographic Surgery Versus Standard Excision: a Prospective Multicentre Cohort Study (British Journal of Dermatology, 2026)

Welcome to This Week in Dermatology. This week we're covering 10 notable papers spanning immune-targeted therapy — where one major trial failed and several others refine how we use the drugs we already have — plus skin cancer surgery and systemic comorbidity, and a final group on infection, prevention and how care gets delivered. Let's dive in.

This week's papers:

1. Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.. British Journal of Dermatology 2026
2. Dose optimization of deuruxolitinib in adults with alopecia areata: A phase 2 randomized trial.. Journal of the American Academy of Dermatology 2026
3. Pediatric Alopecia Areata and JAK Inhibitors: Bridging the Gap Between Evidence and Practice.. Journal of the American Academy of Dermatology 2026
4. Drug Survival of Omalizumab and Factors Associated With Discontinuation in Chronic Urticaria: A Meta-Analysis.. JAMA Dermatology 2026
5. Inflammatory Bowel Disease and Interleukin-17 Inhibitors in Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis.. JAMA Dermatology 2026
6. Five-year Recurrence Rate of Cutaneous Squamous Cell Carcinoma After Mohs Micrographic Surgery Versus Standard Excision: a Prospective Multicentre Cohort Study.. British Journal of Dermatology 2026
7. Blood proteomics links systemic inflammation with early atherosclerosis in moderate-to-severe atopic dermatitis.. Journal of Investigative Dermatology 2026
8. Advances in the diagnosis and management of skin and soft tissue infections.. BMJ 2026
9. Comparison of sunscreen products for babies and children with those for adults.. Dermatology 2026
10. Veterans' Willingness to Use Home-based Telehealth and AI for Dermatology.. Journal of Investigative Dermatology 2026

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