Could Intrinsic Capacity Become the Endpoint for Longevity Drugs?

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Guests:

John Beard

Irene Diamond Professor and Director International Longevity Center USA, Columbia University

LinkedIn: https://www.linkedin.com/in/john-beard-987b801b/

Website: https://www.publichealth.columbia.edu/profile/john-beard-mbbs

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What if the way we measure health is holding back the science of aging?

Phil Newman sits down with Dr. John Beard, Irene Diamond Professor and Director of the International Longevity Centre USA at Columbia University, to explore intrinsic capacity – measuring health through what people can actually be and do rather than the diseases they have.

Together they unpack the five domains of intrinsic capacity and why functional measures could give researchers a more continuous picture of aging. From simple chair-rise and hearing tests to clinical trial endpoints, biomarkers and wearables, Beard explains both the potential and the gaps that remain.

They also discuss why “70 is the new 60,” the difference between prevention and health promotion, why some longevity clinics are ahead of the evidence, and how intrinsic capacity could reshape healthcare funding and drug development.

In this episode, you'll learn:

- Why disease alone is an incomplete measure of aging

- How intrinsic capacity measures cognitive, locomotive, psychological, sensory and vitality domains

- Why better standardized measures could help shorten aging intervention trials

- How early-life health can influence capacity decades later

- Why healthcare systems could eventually reward improvements in health rather than throughput

If you want to understand how measuring function could change geroscience, clinical trials and healthcare itself, this episode connects aging biology with practical measures of how well people actually live.

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Host:

Phil Newman: https://qrco.de/bgXpNY