TWiV 1346: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by Erica Schwartz’ confirmation as CDC director, the GAO proposed pandemic preparedness plans, the national cyclospora outbreak and resulting two deaths, new screwworm and the scale of the Ebola outbreak in the Congo, and clear results from some of President Trump’s policies dismantling public health activites including water safety, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, FDA approval of Moderna’s mRNA vaccine for seasonal flu, how to access and pay for Paxlovid, where to go for answers about long COVID-19, how SARS-CoV-2 infections may reactivate latent viral infections, particularly Aniello virus, and contacting your federal government representative to stop the assault on science and biomedical research.

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Links for this episode

• Senate confirms Erica Schwartz as CDC director (CIDRAP)
• PUBLIC HEALTH PREPAREDNESS: Experts Identified Actions to Improve Surveillance for Emerging Disease Threats (Government Accountability Office)
• Association Between First MMR Vaccination Before Age 2 Years and Childhood Autism in a U.S. EHR Cohort of 2.5 Million Children (The Pediatric Infectious Disease Journal)
• F.D.A. Approves Moderna’s mRNA Flu Vaccine (NY Times)
• Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults (NEJM)
• Two Deaths Linked to Cyclosporiasis in Michigan (NY Times)
• CDC expands largest known cyclosporiasis outbreak to 15 states (Washington Post)
• Surveillance of Cyclosporiasis (CDC: Cyclosporiasis)
• Infectious DiseaseOutbreaks (Michigan: Health & Human Services)
• Cyclosporiasis Cases in North Carolina (North Carolina: Division of Public Health)
• Cyclospora Infection (Cyclosporiasis) (NYC Health)
• Missouri Communicable Disease Report (2026) (Missouri Health)
• Irrigation & Water Use (USDA: Economic Research Service)
• A Guide to OSHA’s Field Sanitation Standard (OSHA)
• Turm purge at FDA and USDA triggers food safety ‘brain drain’ (FOODNavigator)
• Foodborne Illness Surveillance Systems (CDC)
• About Campylobacter infection (CDC: Campylobacter infection (Campylobacteriosis))
• About Cyclosporiasis (CDC: Cyclosporiasis)
• About Listeria Infection (CDC: Listeria Infection (Listeriosis))
• About Salmonella Infection (CDC: Salmonella Infection (Salmonellosis))
• About Escherichia coli Infection (CDC: E.Coli Infection (Escherichia coli))
• About Shigella Infection (CDC: Shigella-Shigellosis)
• About Vibrio Infection (CDC: Vibrio Infection (Vibriosis))
• About Yersinia Infection (CDC: Yersinia Infection (Yersiniosis))
• CDC Reveals Cause of Malaria’s Return to US After 20 Years(Newsweek)
• Trump Dismantles USAID: Experts Say Move Will Help America’s Rivals and Harm Millions (Newsweek)
• What we truly know about the huge US Cyclospora outbreak—and what we don’t (CIDRAP)
• It’s The Water, Not Produce, Likely Driving Cyclospora Outbreaks (Forbes)
• Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service)
• CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom)
• Ebola dashboard (ebola.fyi)
• EBOLA: The Democratic Republic of the Congo, 2026(WHO)
• Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo)
• Ebola Outbreak: Current Situation (CDC:Ebola)
• EXCLUSIVE: Congo’s Ebola epidemic started at least 4 months before it was detected (Science)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Measles (VDH: Virginia Department of Health)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Moderna’s mRNA flu shot mFlusiva snags FDA nod after refusal-to-file imbroglio (Fierece Pharma)
• Weekly surveillance report: clift notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Household Transmission of SARS-CoV-2 in Washington and Oregon, United States, 2022-2024 (Journal of the Pediatric Infectious Diseases Society)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin’s evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Virus reactivation in acute and long COVID-19 (Nature)
• Reaching out to US house representative
• Letters read on TWiV 1346
• Dr. Griffin’s COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

Content in this podcast should not be construed as medical advice.