EASL DeepDive: AI-Enabled Clinical Trials: Opportunities, Evidence and Oversight

Artificial intelligence (AI) is opening new opportunities to improve the design, efficiency, and evidence generation of clinical trials. This EASL DeepDive examines its applications in patient selection, stratification, and trial workflows, as well as the emerging role of digital twins in simulating treatment responses. Particular attention is given to the use of AI-enabled real-world data to strengthen clinical evidence, while addressing questions of scientific validity, bias, and practical limitations.