Immune
- Folgen
- 148
- Erscheint
- alle zwei Wochen
- Letzte Folge
- 10. Nov. 2026
Über den Podcast
A podcast about the body's defenders against disease.
Folgen 148
Immune Booster 39: Diet, aging, obesity, and immunity with Emily Goldberg
Emily Goldberg joins Immune at the annual AAI conference to discuss her groundbreaking research on ketogenic diets and T cells, fasting and obesity, molecular signals that regulate inflammation, and the biology …
Shownotes
Emily Goldberg joins Immune at the annual AAI conference to discuss her groundbreaking research on ketogenic diets and T cells, fasting and obesity, molecular signals that regulate inflammation, and the biology of healthy aging. Host: Cindy Leifer
Guest: Emily Goldberg
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Links for this episode- MicrobeTV Discord Server
- Ketone bodies trigger immune responses (Am J Physiol Cell Physiol, 2024)
- Ketogenic diet protects against flu infection (Sci Immunol, 2019)
- HDACs catalyze lacylation (J Biol Chem 2025)
- Immunometabolic response to fasting (iScience, 2025)
- Immune-metabolic preservation of healthy aging (Tansl Med Aging, 2020)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 109: Allergic to red meat? Scientists discover a potential new treatment
On this episode of Immune, the team explores two fortuitous discoveries: caspase inhibitors that hitch a ride through gasdermin D pores to selectively shut down proinflammatory cytokine secretion, and human …
Shownotes
On this episode of Immune, the team explores two fortuitous discoveries: caspase inhibitors that hitch a ride through gasdermin D pores to selectively shut down proinflammatory cytokine secretion, and human monoclonal antibodies against malaria that were repurposed to block allergic antibody binding to red meat allergens in alpha-gal syndrome.
Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker
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Links for this episode- MicrobeTV Discord Server
- GasderminD pores deliver drugs (Nature, 2026)
- Potential alpha-gal syndrome treatment (J Clin Immunol, 2026)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 38: Fascination with Flavivirus B cell responses with Tulika Singh
Tulika Singh joins Immune at AAI2026 to talk about the international partnerships that advance research on immunity to emerging flaviviruses and her research on the impact of prior Zika virus infection on …
Shownotes
Tulika Singh joins Immune at AAI2026 to talk about the international partnerships that advance research on immunity to emerging flaviviruses and her research on the impact of prior Zika virus infection on susceptibility to Dengue virus disease.
Host: Cindy Leifer
Guest: Tulika Singh
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Links for this episode- MicrobeTV Discord Server
- Harris Research Lab
- 2025 STAT Wunderkind award to Dr. Singh
- Neutralization of Zika with IgM developed in pregnancy (Cell, 2022)
- Infection history shapes Dengue response (Nat Comm, 2024)
- Longitudinal profiling of antibodies following Dengue infection (Nat Comm, 2026)
- Exposure to Zika and risk for Dengue (Sci Transl Med, 2024)
- AAI Public Policy Fellows Program
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 36: Innate immune brakes with Carla Rothlin
Carla Rothlin joins Immune at AAI2026 to talk about her career studying inflammation regulation and how she co-founded the Global Immunotalks virtual seminar series. Host: Cindy Leifer Guest: Carla Rothlin …
Shownotes
Carla Rothlin joins Immune at AAI2026 to talk about her career studying inflammation regulation and how she co-founded the Global Immunotalks virtual seminar series.
Host: Cindy Leifer
Guest: Carla Rothlin
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- TAM receptor signaling in immune homeostasis (Annu Rev Immunol, 2015)
- MerTk in retinal pigment epithelial cells (Sci Adv, 2023)
- Modifiers determine MerTk function (Elife, 2022)
- Re-evaluating MerTk knockout mice (Int J Mol Sci, 2024)
- TAMs for checkpoint blockade in cancer therapy (Immunol Rev, 2017)
- Global Immunotalks on YouTube
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 108: B cells go broad and live long
Immune tackles papers on the breadth of human B cell responses following mRNA vaccination and on the role of mitochondria and reactive oxygen species in plasma B cell maintenance. Hosts: Vincent Racaniello …
Shownotes
Immune tackles papers on the breadth of human B cell responses following mRNA vaccination and on the role of mitochondria and reactive oxygen species in plasma B cell maintenance.
Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- mRNA flu vaccine expands B cell breadth (Nat Immunol, 2026)
- Mitochondrial ROS and plasma cells (Nat Commun, 2026)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 37: Secret lives of neutrophils with Tanya Mayadas
Tanya Mayadas joins Immune to talk about her road to study neutrophils and her research findings on neutrophil antigen presentation and novel neutrophil targeting therapies. Host: Cindy Leifer Guest: Tanya …
Shownotes
Tanya Mayadas joins Immune to talk about her road to study neutrophils and her research findings on neutrophil antigen presentation and novel neutrophil targeting therapies.
Host: Cindy Leifer
Guest: Tanya Mayadas
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Tanya recently appointed department chair and director
- Neutrophils, von Willebrand factor and P-selectin (Cell, 1991)
- P-selectin knockout mouse (Cell, 1993)
- Neutrophils as antigen presenting cells in cancer (Nat Comm, 2021)
- Neutrophils elicit broad anti-tumor immunity (Cancer Res Comm, 2026)
- FcR-mediated neutrophil recruitment (Circulation, 2009)
- Neutrophil classification and heterogeneity (Immunity, 2025)
- Neutrophils in Lupus (Curr Op Rheumatol, 2019)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 35: Human immunology and Dengue virus infection with Adam Waickman
Adam Waickman discusses the unusual reason he got into studying immunology just in humans, his important studies on Dengue virus vaccine antibodies, and the problematic phenomenon of antibody dependent …
Shownotes
Adam Waickman discusses the unusual reason he got into studying immunology just in humans, his important studies on Dengue virus vaccine antibodies, and the problematic phenomenon of antibody dependent enhancement.
Host: Cindy Leifer
Guest: Adam Waickman
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Waickman Lab Website
- Dengue virus human infection model (Sci Trans Med, 2022)
- mRNA vectored antibody against Dengue (Antiviral Res, 2025)
- B cell receptor enhancement of Dengue (PLoS Path, 2024)
- Dengue infection macrophage transcriptional profiles (J Virol, 2025)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 107: Breakfast of champions
Immune reviews new research that shows a boost in T cell function after eating and the potential for the cGAS-STING pathway to be a new lupus therapeutic target. Hosts: Vincent Racaniello, Cindy Leifer …
Shownotes
Immune reviews new research that shows a boost in T cell function after eating and the potential for the cGAS-STING pathway to be a new lupus therapeutic target.
Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne BarkerSubscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- T cell immunity boosted after eating (Nature, 2026)
- Inhibiting autoimmunity through TLR7-cGAS (Nat Comm, 2026)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 34: Decoding antiviral signaling networks with Stacy Horner
Stacy Horner discusses her work on innate detection of viruses, viral countermeasures, and the role of m(6)A RNA modifications in regulating antiviral immunity. Host: Cindy Leifer Guest: Stacy Horner Subscribe …
Shownotes
Stacy Horner discusses her work on innate detection of viruses, viral countermeasures, and the role of m(6)A RNA modifications in regulating antiviral immunity.
Host: Cindy Leifer
Guest: Stacy Horner
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Hepatitis virus proteases block host response (J Virol, 2012)
- Host RNA binds to MAVS (Science, 2024)
- m6A modifications modify innate response to viruses (Cell Chem Biol, 2024)
- UFMylation coordinates MAVS assembly for antiviral responses (bioRxiv, 2025)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 33: Immunity to pesky parasites and peanuts with Scott Smith
Scott Smith talks about his research on cloned individual antibodies and how those studies have shifted his thoughts on the role of IgE in parasite defense and food allergy. Host: Cindy Leifer Guest: Scott …
Shownotes
Scott Smith talks about his research on cloned individual antibodies and how those studies have shifted his thoughts on the role of IgE in parasite defense and food allergy.
Host: Cindy Leifer
Guest: Scott Smith
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Complement control proteins in poxvirus evasion (J Virol, 2000)
- Complement control protein reduces xenotransplant rejection (Transpl Proc, 2002)
- Engineering therapeutic antibodies (J Allergy Clin Immunol, 2023)
- Antigens in peanut allergy anaphylaxis (J Allergy Clin Immunol, 2025)
- Using human antibodies to identify parasite antigens (J Allergy Clin Immunol, 2022)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 106: Science and podcasting with Kathryn Knoop and Marion Brunck
Kathryn Knoop and Marion Brunck join the Immune team to talk about their research and their podcast "Mucosal Immunology". Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker Guests …
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Kathryn Knoop and Marion Brunck join the Immune team to talk about their research and their podcast "Mucosal Immunology".
Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne BarkerGuests: Kathryn Knoop and Marion Brunck
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Links for this episode- MicrobeTV Discord Server
- Knoop: Oral tolerance in early life review
- Knoop: Gamma delta T cells in neonatal sepsis
- Knoop: EGF and IgA in breastmilk
- Brunck: FcGR's in PMNS
- Brunck: CRISPR KO to study FcGR's in human PMN
- Brunck: Leukocytes in breastmilk review
- Mucosal Immunology podcast
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 32: Natural infection versus vaccine protection with Jenna Guthmiller
Jenna Guthmiller talks about how she became interested in immunology and her exciting research on how different responses to vaccines and infection shape future responses to infection. Host: Cindy Leifer Guest …
Shownotes
Jenna Guthmiller talks about how she became interested in immunology and her exciting research on how different responses to vaccines and infection shape future responses to infection.
Host: Cindy Leifer
Guest: Jenna Guthmiller
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Broadly neutralizing flu antibodies (Nature, 2022)
- First exposure antibodies to H1N1 flu (Sci Transl Med, 2021)
- Long lasting B cells to chimeric flu vaccine (Immunity, 2025)
- Vaccine strategies to target HA anchor epitope (Nat Comm, 2025)
- Pre-existing immunity shapes flu response (Sci Trans Med, 2020)
- From Immune 35: SARS-CoV-2 infection severity linked to anti-spike (mBio, 2021)
- Guthmiller lab
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 105: Tumor bacteria undermine immunotherapy
Immune discusses a snippet on how EBV infection alters the immunopeptidome and promotes multiple sclerosis, and a paper on head and neck cancers harboring bacteria that create an immunosuppressive environment …
Shownotes
Immune discusses a snippet on how EBV infection alters the immunopeptidome and promotes multiple sclerosis, and a paper on head and neck cancers harboring bacteria that create an immunosuppressive environment and promote immunotherapy resistance.
Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker
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Links for this episode- MicrobeTV Discord Server
- EBV, Golli-MBP presentation and multiple sclerosis (Cell, 2026)
- Intratumoral bacteria promote resistance to cancer immunotherapy (Nat Cancer, 2026)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 31: NOD-like receptor discovery with Gabriel Nunez
Gabriel Nunez discusses the discovery of NOD-like receptors, NOD1 and NOD2, in inflammatory bowel disease and how travel and taking a moment to enjoy local culture and art influences his creativity. Host: Cindy …
Shownotes
Gabriel Nunez discusses the discovery of NOD-like receptors, NOD1 and NOD2, in inflammatory bowel disease and how travel and taking a moment to enjoy local culture and art influences his creativity.
Host: Cindy Leifer
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- HLA and antigen presentation (Hum Immunol, 1987)
- Bcl2, cell death, and B cells (Nature, 1991)
- Discovery of NOD1 (J Biol Chem, 1999)
- Discovery of NOD2 (J Biol Chem, 2001)
- Mutation in NOD2 and connection to Crohn's disease (Nature, 2001)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 30: Infant Immunology with Martha Alexander-Miller
Martha Alexander-Miller discusses why newborn and infant immune responses to vaccines are generally less effective and how we can make vaccines safer and more effective. Host: Cindy Leifer Guest: Martha …
Shownotes
Martha Alexander-Miller discusses why newborn and infant immune responses to vaccines are generally less effective and how we can make vaccines safer and more effective.
Host: Cindy LeiferGuest: Martha Alexander-Miller
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Flu HA nanoparticle vaccine (Nat Comm, 2025)
- Sex-dependent adjuvant activity in newborns (Vaccines, 2024)
- Flu vaccine with R848 adjuvant (Vaccines, 2023)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 104: All about allergies
The Immune team talks about two papers on the effect of sleep and environment on seasonal allergies. Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email …
Shownotes
The Immune team talks about two papers on the effect of sleep and environment on seasonal allergies.
Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Sleep is needed for condition dependent allergic responses (PNAS, 2020)
- Original paper on allergy to artificial rose (Am. J. Med. Sci. 181, 45–56 (1886))
- One of multiple personalities allergic (Am J Clin Hypn, 1983)
- Environmentally driven immune imprinting protects against allergy (Nature, 2026)
- News and Views on immune imprinting paper (Nature, 2026)
- Immune 90 discussion of "dirty mice"
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Matters Microbial #130: The Holobiont — Animals, Microbes, and Ecology
Matters Microbial #130: The Holobiont — Animals, Microbes, and Ecology May 19, 2026 Today Dr. Kevin Kohl, Associate Professor of Biological Sciences at the University of Pittsburgh, joins the #QualityQuorum to …
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Matters Microbial #130: The Holobiont — Animals, Microbes, and Ecology May 19, 2026Today Dr. Kevin Kohl, Associate Professor of Biological Sciences at the University of Pittsburgh, joins the #QualityQuorum to discuss how he and his colleagues study the interplay between animals, their resident gut microbes, and the overarching concept of the holobiont.
Host: Mark O. Martin
Guest: Kevin Kohl
Subscribe: Apple Podcasts, Spotify
Become a patron of Matters Microbial!
Links for this episode- The One Health Microbiome Center at Pennsylvania State University.
- A very fine essay on the holobiont concept for non-microbiologists.
- A general introductory overview of the holobiont concept.
- The holobiont concept and the coral symbiosis.
- A partial history of the development of the holobiont concept.
- Dr. Casadevall suggests that context and thus outcomes describes the term "pathogen," and a similar analysis applies to the holobiont.
- A very short description of the holobiont concept.
- Another overview of the holobiont concept in general, coauthored by Dr. Kohl.
- Some basic rules for thinking about the holobiont concept.
- A video introduction to the holobiont concept, by Dr. Seth Bordenstein.
- I highly recommend this essay by the science writer Carl Zimmer, "The Human Lake," to think of the connections between lake ecology and microbial interactions with humans.
- Another wonderful article recommended by Dr. Kohl, by Dr. Margaret McFall-Ngai and coauthors, detailing the impact microbes have on animals over evolution and development.
- The wood rat – creosote – microbiome connection to the holobiont concept, discussed on this podcast (coauthored by Dr. Kohl).
- The fascinating work by Dr. Kohl and colleagues showing the relationship between tadpole development and pond microbes discussed in this podcast.
- A must read article by Dr. Kohl and colleagues, "Through the microbial looking glass: our shifting understanding of the holobiont and microbes as mediators of organismal biology," illustrates the development and influence of the holobiont concept.
- Dr. Richard Prum's book, "Performance All the Way Down," was discussed during this podcast. There is also a video where Dr. Prum discusses the ideas in this book, describing gene regulation as a performance.
- Dr. Kohl's faculty website.
- Dr. Kohl's (very interesting) research website.
Intro music is by Reber Clark
Send your questions and comments to [email protected]
Immune Booster 29: Immune regulation and science communication with Nicholas Jackson
Nicholas Jackson, AKA Nick the Immunologist, talks about being a graduate student, social media creator, and his research on cytokine tools to investigate regulatory T cells. Host: Cindy Leifer Guest: Nicholas …
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Nicholas Jackson, AKA Nick the Immunologist, talks about being a graduate student, social media creator, and his research on cytokine tools to investigate regulatory T cells.
Host: Cindy Leifer
Guest: Nicholas Jackson (Nick the Immunologist)
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Richard DiPaolo lab
- IL-2, TGFb and Tregs preprint
- Nick the Immunologist on TikTok
- Nick the Immunologist on Instagram
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 28: Immunometabolism, Inflammation, and Building Biotechs with Luke O'Neill
Luke O'Neill recounts his role in discovering key components of the TLR signaling pathway, explains how pursuing unexpected research questions keeps him motivated, and reflects on his experiences as an …
Shownotes
Luke O'Neill recounts his role in discovering key components of the TLR signaling pathway, explains how pursuing unexpected research questions keeps him motivated, and reflects on his experiences as an entrepreneur founding biotech companies.
Host: Cindy Leifer
Guest: Luke O'Neill
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- O'Neill lab
- Identification of MAL in the TLR signaling pathway (Nature, 2001)
- GDF 15, immunometabolism and anti-inflammatories (An Rev Pharmacol Tox, 2026)
- Itaconate and regulation of inflammation (Nat Metab, 2024)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 27: Interferons, JAKs, and STATs with George Stark
George Stark from the Cleveland Clinic reflects on his early training in biochemistry and how several sabbatical leaves sparked pivotal changes in his research trajectory, eventually drawing him to interferon …
Shownotes
George Stark from the Cleveland Clinic reflects on his early training in biochemistry and how several sabbatical leaves sparked pivotal changes in his research trajectory, eventually drawing him to interferon signaling where he helped establish the core principles of the JAK–STAT pathway and uncovered interesting roles for interferon signaling in cancer.
Host: Cindy Leifer
Guest: George Stark
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Links for this episode- MicrobeTV Discord Server
- Stark lab
- Development of the Northern blotting technique (PNAS, 1977)
- Development of Western blotting for proteins (PNAS, 1979)
- Discovery of Tyk2 as a critical kinase in interferon response (Cell, 1992)
- Topical PALA treatment for non-melanoma skin cancer (Exp Dermatol, 2023)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 103: Cytokines 101
The Immune team talks all about cytokines, from what they are to immunotherapies against them to treat diseases. Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker Subscribe (free): Apple Podcasts …
Shownotes
The Immune team talks all about cytokines, from what they are to immunotherapies against them to treat diseases.
Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Non-specific virus neutralization by IgM and complement (mBio 2026)
- Natural antibodies against viruses (Virology blog, 2009)
- Biologics against inflammatory cytokines (Int J Cell Bio, 2016)
- Biologics against allergic cytokines (JACI, 2022)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 26: Immune defense against parasitic worms with Irah King
Irah King from McGill University talks about his passion to understand how our immune system detects and responds to helminthic worm infections, how the worms can reprogram those responses, and how these …
Shownotes
Irah King from McGill University talks about his passion to understand how our immune system detects and responds to helminthic worm infections, how the worms can reprogram those responses, and how these pathways might be exploited to develop new treatments for inflammatory diseases.
Host: Cindy Leifer
Guest: Irah King
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- King lab at McGill
- Stromal cells and disease tolerance against intestinal infection (Cell, 2025)
- Helminth-Microbiome Interactions in Early Life (Cell, Host, & Microbe, 2024)
- BCL6, CD4T cells and parasitic infection (Mucoslal Immunol, 2023)
- Helminths manipulate the intestinal epithelium (Trends Parasit, 2023)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune102: Living longer without B cells
The Immune team discusses a paper describing the negative effects of old B cells on T cells and longevity and a snippet on an interesting vaccine approach to promote competition between gut commensals. Hosts …
Shownotes
The Immune team discusses a paper describing the negative effects of old B cells on T cells and longevity and a snippet on an interesting vaccine approach to promote competition between gut commensals.
Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Vaccine enhanced competition of gut bacteria (Science 2025)
- B cells drive immunosenescence and aging (Sci Immunol 2026)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 25: Out of the anti-vax woods with Ellen Woods
A former anti-vax mom talks about going down the rabbit hole, her mindset shift, the importance of doctors who are willing to talk with patients about vaccines, and why she is now a vaccine advocate. Host …
Shownotes
A former anti-vax mom talks about going down the rabbit hole, her mindset shift, the importance of doctors who are willing to talk with patients about vaccines, and why she is now a vaccine advocate.
Host: Cindy Leifer
Guest: Ellen Mary Woods
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- A shot at life foundation
- Voices for Vaccines information and advocacy
- What the iPhone bendgate can teach us about vaccine hesitancy
- Tips for conversations with vaccine hesitant people
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 24: Tolerating pregnancy with Gabrielle Rizzuto
Gabrielle Rizzuto from Memorial Sloan Kettering Cancer Center discusses her work on the curious immunology of pregnancy and how a woman tolerates a genetically different baby but quickly rejects a mismatched …
Shownotes
Gabrielle Rizzuto from Memorial Sloan Kettering Cancer Center discusses her work on the curious immunology of pregnancy and how a woman tolerates a genetically different baby but quickly rejects a mismatched organ donation.
Host: Cindy Leifer
Guest: Gabrielle Rizzuto
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Rizzuto lab at MSKCC
- Tolerance at the fetal-maternal interface (Nature, 2022)
- The paradox of fetal-maternal tolerance (J Exp Med, 2022)
- Spatially resolved timeline of fetal-maternal interface (Nature, 2023)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 101: Ink and immunity
Immune discusses how tattoo ink accumulates in lymph nodes, promotes inflammation and influences response to two different vaccines. Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker …
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Immune discusses how tattoo ink accumulates in lymph nodes, promotes inflammation and influences response to two different vaccines.
Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- IL-9, CAR T cells and anti-tumor CD8 cells
- Tattoo ink, inflammation and vaccines
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 23: Critical windows during immune system development with Anna Beaudin
Anna Beaudin from University of Utah talks about the key thread of her career, development, and how that influences her research on the events happening during critical prenatal windows shapes everything from …
Shownotes
Anna Beaudin from University of Utah talks about the key thread of her career, development, and how that influences her research on the events happening during critical prenatal windows shapes everything from the developing immune system to hearing loss.
Host: Cindy Leifer
Guest: Anna Beaudin
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Beaudin lab at University of Utah
- PhD work on metabolism and development
- Postdoc work on hematopoietic stem cells
- Maternal inflammation and hematopoietic stem cell development
- Prenatal inflammation effect on postnatal immunity
- Early life inflammation and hearing loss
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster #22 T cell signaling and selection with Leslie Berg
Leslie Berg talks about her career studying T cell receptor signaling, T cell development, and the importance of mentors in her career. Host: Cindy Leifer Guest: Leslie Berg Subscribe (free): Apple Podcasts …
Shownotes
Leslie Berg talks about her career studying T cell receptor signaling, T cell development, and the importance of mentors in her career.Host: Cindy Leifer
Guest: Leslie Berg
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Berg lab at University of Colorado Anschutz
- TCR thresholds and ITK (PNAS)
- Review on TCR signaling (Nat Immunol)
- Generation of TCR transgenic mice (Mol Cell Bio)
- T cell negative selection in TCR transgenic mice (Nature)
- Thymic exit of mature T cells in TCR transgenic mice (Cell)
- AAI past president Berg information
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune 100: Immune turns 100!
The whole Immune gang gathers with special guests Gretchen Diehl and Shruti Naik at The Incubator with an audience to celebrate the 100th episode. Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and …
Shownotes
The whole Immune gang gathers with special guests Gretchen Diehl and Shruti Naik at The Incubator with an audience to celebrate the 100th episode.
Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker
Guests: Gretchen Diehl and Shruti Naik
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Diehl: Gut microbe-specific T cell development (Nature 2021)
- Diehl: Bacteria-induced IL-1 is gut protective (Gut Microbes 2022)
- Diehl: Microbiota, macrophages, IL10, and colitis (Gut Microbes 2022)
- Diehl: E. coli-activated circuit restrains gut inflammation (Cell Rep 2025)
- Naik: Commensals control skin inflammation (Science 2012)
- Naik: IL-17 and hypoxic stress during skin repair (Science 2022)
- Naik: Human psoriasis and spatial transcriptomics (Sci Immunol 2023)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami.
Immune logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
Immune Booster 21: Origins of antigen receptors with David Schatz
David Schatz talks about his discovery of Rag genes that are critical for antigen receptor development and how that discovery depended on taking high risks and using approaches that everyone thought could never …
Shownotes
David Schatz talks about his discovery of Rag genes that are critical for antigen receptor development and how that discovery depended on taking high risks and using approaches that everyone thought could never work.
Host: Cindy Leifer
Guest: David Schatz
Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune!
Links for this episode- MicrobeTV Discord Server
- Transfer of recombinase activity in non-lymphoid cells (Cell 1988)
- Identification of the RAG-1 gene (Cell 1989)
- Evolution of a recombinase (Semin Immunol 2004)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to [email protected]
Information on this podcast should not be construed as medical advice.
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