NEJM This Week — October 29, 2026

This week, we feature new research on renal-replacement therapy for acute kidney injury, cardiac monitoring for unexplained syncope, and treatments for COPD and type 2 diabetes. We review antibiotic resistance in gram-negative bacteria and follow a complicated case of hemorrhage during pregnancy. Perspectives explore health care regulation, access to reproductive care, and the deeply personal decisions surrounding end-of-life care.