'Decoding the immune system' with 2025 medicine laureates: Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi

Patience, persistence and a strong will for never giving up. Discovering how the immune system is kept in check demanded a lot of our 2025 medicine laureates.

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi spent years finding out how our body's powerful immune system is regulated – leading to the development of medical treatments for cancer and autoimmune diseases.

Join us for our conversation where we unravel the achievements behind the 2025 Nobel Prize in Physiology or Medicine.

For a quick introduction to 2025’s awarded discovery in physiology or medicine, check out our Crash Course on regulatory T-cells or Olle Kämpe’s eloquent speech from the Nobel Prize award ceremony.

Read complete profiles of Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi, and explore the 2025 Nobel Prize in Physiology or Medicine at our website, nobelprize.org.

See the announcement of the Nobel Prize in Physiology or Medicine 2025 and the moment Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi were awarded their medals, all available on YouTube.

This podcast was a production of Nobel Prize Outreach and Filt, and created in cooperation with Fundación Ramón Areces.

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