Altered thalamo-prefrontal synchrony dynamics during spatial working memory task performance in a SETD1A loss-of-function mouse model of schizophrenia predisposition

Joshua Gordon is a professor and chair of the Department of Psychiatry at Columbia University, and one of the authors of a new study in the journal Neuropsychopharmacology. There can be a strong genetic risk factor for schizophrenia, and loss of function mutations in the gene SETDIA raise the risk of schizophrenia by about 60-80 fold, a dramatic increase in risk. Sofiya Hupalo is the clinical and regulatory science lead at the Usona Institute and is another one of the study’s authors.

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