Real Life Pharmacology – Pharmacology Education for Health Care Professionals
- Folgen
- 485
- Erscheint
- wöchentlich
- Letzte Folge
- 12. Nov. 2026
Über den Podcast
A Meded101.com Production
Folgen 485
Parkinson’s Disease – Part 1; Sinemet Practice Pearls and Test Prep
In this episode of Real Life Pharmacology, we take a closer look at Parkinson’s disease and one of its most important treatments, Sinemet (carbidopa/levodopa). We review the pathophysiology of Parkinson’s, how …
Shownotes
In this episode of Real Life Pharmacology, we take a closer look at Parkinson’s disease and one of its most important treatments, Sinemet (carbidopa/levodopa). We review the pathophysiology of Parkinson’s, how carbidopa and levodopa work together to improve dopamine levels in the brain, and important clinical practice pearls for prescribing and managing therapy. We also discuss dosing considerations, timing of administration, available dosage forms, and strategies to help optimize symptom control while minimizing adverse effects.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Gout Pharmacotherapy – Test Prep and Practice Pearls
Gout pharmacotherapy involves more than just treating painful flare-ups. In this episode of Real Life Pharmacology, we review the most commonly used gout medications, including allopurinol, febuxostat …
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Gout pharmacotherapy involves more than just treating painful flare-ups. In this episode of Real Life Pharmacology, we review the most commonly used gout medications, including allopurinol, febuxostat, colchicine, probenecid, NSAIDs, and corticosteroids. Learn how these medications work, their indications, important adverse effects, clinically significant drug interactions, and practical prescribing pearls. We also discuss uric acid treatment goals, prevention of recurrent gout attacks, renal dosing considerations, and important medication safety concerns. Whether you are a pharmacist, nurse, physician, or healthcare professional preparing for a board certification exam, this episode will help strengthen your understanding of gout treatment and evidence-based gout pharmacotherapy.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Osteoporosis Medications Part 2 – Test Prep and Practice Pearls
Bisphosphonates are commonly used to treat osteoporosis, but several non-bisphosphonate osteoporosis medications can help reduce fracture risk. Pharmacists should understand the mechanisms, adverse effects, and …
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Bisphosphonates are commonly used to treat osteoporosis, but several non-bisphosphonate osteoporosis medications can help reduce fracture risk. Pharmacists should understand the mechanisms, adverse effects, and clinical pearls associated with these alternatives. On this podcast episode, I will cover four of the most commonly used “non-bisphosphonate” osteoporosis medications.
Denosumab (Prolia) is a RANKL inhibitor that decreases osteoclast activity and bone resorption. It is administered subcutaneously every six months.
Teriparatide (Forteo) and abaloparatide (Tymlos) stimulate bone formation through the parathyroid hormone pathway. These medications may be appropriate for patients at very high fracture risk.
Raloxifene (Evista) is a selective estrogen receptor modulator (SERM) that reduces bone resorption. It primarily reduces vertebral fracture risk and may lower the risk of estrogen receptor-positive breast cancer. Important adverse effects include hot flashes and an increased risk of venous thromboembolism.
Calcitonin (Miacalcin) inhibits osteoclast-mediated bone resorption. However, its effectiveness for fracture prevention is limited, making it a less-preferred option for long-term osteoporosis treatment.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Osteoporosis Medications – Test Prep and Practice Pearls: Bisphosphonates
Bisphosphonates are commonly used to prevent and treat osteoporosis, making them an important topic for pharmacy, nursing, and medical exams. In this episode of the Real Life Pharmacology Podcast, we review …
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Bisphosphonates are commonly used to prevent and treat osteoporosis, making them an important topic for pharmacy, nursing, and medical exams. In this episode of the Real Life Pharmacology Podcast, we review high-yield bisphosphonate facts and practical pearls to help you prepare for exams and improve medication management.
Topics covered include:
- Key differences between alendronate, risedronate, ibandronate, and zoledronic acid
- Mechanism of action and how bisphosphonates reduce bone resorption
- Dosing schedules and important administration instructions
- Common adverse effects, including gastrointestinal irritation
- Osteonecrosis of the jaw and atypical femoral fractures
- Renal function considerations and important contraindications
- Drug interactions and tips to improve medication absorption
Whether you are preparing for a pharmacy board exam, studying pharmacology, or reviewing osteoporosis treatment in clinical practice, this episode highlights the key bisphosphonate concepts worth remembering.
Listen to the Real Life Pharmacology Podcast for practical medication insights that help connect pharmacology knowledge with real-world patient care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
NSAIDs Part 3 – Test Prep and Practice Pearls; Nabumetone, Diclofenac, Meloxicam, Piroxicam, Etodolac, Indomethacin, Sulidac, and Ketorolac
In this episode of Real Life Pharmacology, we take a closer look at several NSAIDs that are commonly encountered in clinical practice: nabumetone, diclofenac, meloxicam, piroxicam, etodolac, indomethacin …
Shownotes
In this episode of Real Life Pharmacology, we take a closer look at several NSAIDs that are commonly encountered in clinical practice: nabumetone, diclofenac, meloxicam, piroxicam, etodolac, indomethacin, sulindac, and ketorolac.
These medications may all belong to the same general class, but they have important differences in dosing, adverse effects, drug interactions, and clinical use. We’ll discuss which NSAIDs tend to be more COX-2 selective, which ones carry significant gastrointestinal or cardiovascular concerns, and why some agents are used much more cautiously than others.
We’ll also cover practical pharmacology pearls for medications such as indomethacin, which is commonly used for acute gout, ketorolac, which is generally reserved for short-term pain management, and diclofenac, which has important cardiovascular considerations.
Whether you’re studying for a pharmacology exam, working with patients, or simply want to strengthen your knowledge of NSAIDs, this episode focuses on the clinically relevant points you need to know about these eight medications.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
NSAIDs Part 2 – Test Prep and Practice Pearls for Aspirin, Ibuprofen, Naproxen, and Celecoxib
Aspirin, ibuprofen, naproxen, and celecoxib are some of the most commonly used NSAIDs, but they are not interchangeable when it comes to safety, indications, and patient-specific risks. In this episode of Real …
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Aspirin, ibuprofen, naproxen, and celecoxib are some of the most commonly used NSAIDs, but they are not interchangeable when it comes to safety, indications, and patient-specific risks. In this episode of Real Life Pharmacology, we compare these four medications and highlight the key differences pharmacists and other healthcare professionals need to know.
We’ll review how NSAIDs work, including COX-1 and COX-2 inhibition, and discuss their effects on pain, inflammation, platelets, the gastrointestinal system, kidneys, cardiovascular system, and fluid balance. We’ll also compare the GI, cardiovascular, renal, and heart failure risks of aspirin, ibuprofen, naproxen, and celecoxib.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
NSAIDs Part 1 – Test Prep and Practice Pearls
On this podcast episode, I cover the basics of NSAIDs, including how they work, what they are used for, significant drug interactions, and what adverse effects are important to monitor. I’ll educate about some …
Shownotes
On this podcast episode, I cover the basics of NSAIDs, including how they work, what they are used for, significant drug interactions, and what adverse effects are important to monitor. I’ll educate about some of the major risks associated with NSAIDs and what I look out for as a practicing pharmacist.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Opioids Part 5 – Tramadol, Tapentadol, and Meperidine
In this episode of Real Life Pharmacology, we’re taking a closer look at three unique opioids: tramadol, tapentadol, and meperidine. These medications have some important differences in their mechanisms …
Shownotes
In this episode of Real Life Pharmacology, we’re taking a closer look at three unique opioids: tramadol, tapentadol, and meperidine. These medications have some important differences in their mechanisms, clinical uses, drug interactions, and safety concerns. We’ll review the key pharmacology and practical clinical pearls you should know when using these opioids in real-world practice.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Opioids Part 4 – Methadone and Buprenorphine
In this episode of Real Life Pharmacology, we’re taking a closer look at two unique opioids: methadone and buprenorphine. Both medications have important roles in pain management and opioid use disorder, but …
Shownotes
In this episode of Real Life Pharmacology, we’re taking a closer look at two unique opioids: methadone and buprenorphine. Both medications have important roles in pain management and opioid use disorder, but their pharmacology, dosing, drug interactions, and safety considerations are quite different. We’ll review the key clinical pearls you need to know when using these medications in real-world practice.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Opioids Part 3 – Test Prep and Practice Pearls – Codeine and Fentanyl
On this podcast episode, we will explore the most important practice pearls of codeine and fentanyl. Both medications are opioids, but codeine is frequently found in combination with acetaminophen. Fentanyl has …
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On this podcast episode, we will explore the most important practice pearls of codeine and fentanyl. Both medications are opioids, but codeine is frequently found in combination with acetaminophen. Fentanyl has numerous unique dosage forms, including the transdermal formulation which is a source of frequent test questions. I break these two medications down in this podcast episode.
Opioids Part 2 – Test Prep and Practice Pearls
In Part 2 of my series on opioids, I cover hydromorphone, oxycodone, and oxymorphone. Hydromorphone and oxycodone are two opioids that are used frequently in clinical practice, and I will discuss what makes …
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In Part 2 of my series on opioids, I cover hydromorphone, oxycodone, and oxymorphone. Hydromorphone and oxycodone are two opioids that are used frequently in clinical practice, and I will discuss what makes them unique, in addition to numerous other practice pearls and test prep nuggets. Enjoy the podcast and be sure to share it with friends, colleagues, and students!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Opioids Part 1 – Test Prep and Practice Pearls
On part 1 of opioids, I’ll discuss morphine, morphine equivalents, conversion, and hydrocodone. The pharmacokinetic differences will be important between opioids, as well as the dosage forms. I hope you enjoy …
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On part 1 of opioids, I’ll discuss morphine, morphine equivalents, conversion, and hydrocodone. The pharmacokinetic differences will be important between opioids, as well as the dosage forms. I hope you enjoy this podcast episode and share it with your friends!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Skeletal Muscle Relaxants – Test Prep and Practice Pearls
On this episode of the Real Life Pharmacology podcast, I’m going to cover important practice pearls on skeletal muscle relaxants. Important medications that will be covered in this podcast include baclofen …
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On this episode of the Real Life Pharmacology podcast, I’m going to cover important practice pearls on skeletal muscle relaxants. Important medications that will be covered in this podcast include baclofen, cyclobenzaprine, tizanidine, and diazepam.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
GI Antispasmodics – Test Prep and Practice Pearls
Abdominal cramping and intestinal spasms are common complaints in patients with conditions such as irritable bowel syndrome (IBS). Two of the most frequently prescribed medications for these symptoms are …
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Abdominal cramping and intestinal spasms are common complaints in patients with conditions such as irritable bowel syndrome (IBS). Two of the most frequently prescribed medications for these symptoms are dicyclomine and hyoscyamine. These medications work by blocking muscarinic receptors, reducing smooth muscle contractions in the gastrointestinal tract and helping relieve painful spasms.
While these medications can be effective, they are not without risks. Because of their anticholinergic effects, patients may experience dry mouth, constipation, blurred vision, dizziness, and urinary retention. Older adults are particularly susceptible to these adverse effects, making careful patient selection and monitoring especially important. Patients with benign prostatic hyperplasia (BPH), glaucoma, or cognitive impairment may be at higher risk for complications.
In this episode of the Real Life Pharmacology podcast, we’ll review how dicyclomine and hyoscyamine work, discuss their most common clinical uses, compare their adverse effect profiles, and highlight practical education points to help optimize safe and effective use.
Huge thank you to our sponsor – Mechanism of Action Podcast; Go check them out on all your favorite podcast platforms!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Antacids – Test Prep and Practice Pearls
Heartburn is one of the most common gastrointestinal complaints, and antacids remain a go-to option for fast symptom relief. In this episode, we’ll discuss how common antacids like calcium carbonate, magnesium …
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Heartburn is one of the most common gastrointestinal complaints, and antacids remain a go-to option for fast symptom relief. In this episode, we’ll discuss how common antacids like calcium carbonate, magnesium hydroxide, aluminum hydroxide, and sodium bicarbonate work to neutralize stomach acid. We’ll also review their advantages, common adverse effects, important drug interactions, and considerations for patients with kidney disease. Whether you’re a healthcare professional looking for practical clinical pearls or simply want to better understand over-the-counter heartburn medications, this episode provides a concise overview of when antacids are appropriate—and when they may not be the best choice.
Special thanks to the Mechanism of Action Podcast for sponsoring this episode – go check it out!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Gastroparesis Medications – Test Prep and Practice Pearls
Gastroparesis can be a frustrating condition for both patients and clinicians, with symptoms such as nausea, vomiting, early satiety, bloating, and poor glycemic control significantly affecting quality of life …
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Gastroparesis can be a frustrating condition for both patients and clinicians, with symptoms such as nausea, vomiting, early satiety, bloating, and poor glycemic control significantly affecting quality of life. Medication management often requires balancing effectiveness with safety, especially since many commonly prescribed drugs can either improve or worsen gastric emptying. In this episode of the Real Life Pharmacology podcast, we’ll review the medications used to treat gastroparesis, discuss their mechanisms of action, highlight important adverse effects, and identify medications that may contribute to or exacerbate delayed gastric emptying.
Huge thank you to our sponsor – Mechanism of Action Podcast; Go check them out on all your favorite podcast platforms!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
H2 Blockers – Test Prep and Practice Pearls
H2 blockers may not receive as much attention as proton pump inhibitors, but they continue to play an important role in managing acid-related disorders. In this episode of the Real Life Pharmacology podcast …
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H2 blockers may not receive as much attention as proton pump inhibitors, but they continue to play an important role in managing acid-related disorders. In this episode of the Real Life Pharmacology podcast, we’ll review how H2 blockers work, compare the available agents, discuss important adverse effects, renal dose adjustments, drug interactions, and identify the patients who are most likely to benefit from these medications. Whether you’re a pharmacist, nurse, pharmacy technician, physician, or student, this episode provides practical clinical pearls you can apply immediately to patient care.
In this episode, I also discuss a new podcast I discovered – go check out the Mechanism of Action Podcast! It is an entertaining and educational look at how many of the medications used today were discovered and derived.
Proton Pump Inhibitors – Test Prep And Practice Pearls
Proton pump inhibitors (PPIs) are among the most commonly prescribed medications, but understanding how they work is essential for using them safely and effectively. In this episode of the Real Life …
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Proton pump inhibitors (PPIs) are among the most commonly prescribed medications, but understanding how they work is essential for using them safely and effectively. In this episode of the Real Life Pharmacology podcast, we’ll break down the pharmacology of PPIs, including their mechanism of action, common brand and generic names, clinical uses, adverse effects, drug interactions, and important monitoring considerations. Whether you’re a pharmacist, nurse, pharmacy technician, or student, this episode will help reinforce the key concepts you need to confidently apply PPI pharmacology in clinical practice.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Opioid Use Disorder Medications
On this podcast episode, I cover commonly used medications for opioid use disorder. Buprenorphine, methadone, and naltrexone are all potential options in OUD. I’ll discuss the pharmacology of each medication …
Shownotes
On this podcast episode, I cover commonly used medications for opioid use disorder. Buprenorphine, methadone, and naltrexone are all potential options in OUD. I’ll discuss the pharmacology of each medication and the most common practice pearls that will show up in practice and on your board exams.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Alcohol Use Disorder Medications
Naltrexone is often a first-line medication for AUD. It works as an opioid receptor antagonist, reducing the rewarding effects of alcohol and decreasing cravings. Patients frequently report that alcohol becomes …
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Naltrexone is often a first-line medication for AUD. It works as an opioid receptor antagonist, reducing the rewarding effects of alcohol and decreasing cravings. Patients frequently report that alcohol becomes less pleasurable while taking the medication. Oral naltrexone is typically dosed at 50 mg daily, while a long-acting injectable formulation is also available. Avoid use in patients taking opioids and use caution in significant liver dysfunction.
Acamprosate helps maintain abstinence by modulating glutamate and GABA neurotransmission. Chronic alcohol use disrupts the balance between excitatory and inhibitory pathways in the brain, and acamprosate helps restore equilibrium. It is primarily eliminated renally, making it a useful option in patients with liver disease. The most common adverse effect is diarrhea.
Disulfiram works through a completely different mechanism. It inhibits aldehyde dehydrogenase, causing acetaldehyde accumulation when alcohol is consumed. This can lead to flushing, nausea, vomiting, headache, and hypotension. Because of this aversive reaction, patient motivation and adherence are critical for success.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Monoamine Oxidase Inhibitors – Test Prep and Practice Pearls
In this episode, we explore monoamine oxidase inhibitors (MAOIs), one of the oldest yet most effective classes of antidepressants. We discuss how MAOIs such as phenelzine, tranylcypromine, isocarboxazid, and …
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In this episode, we explore monoamine oxidase inhibitors (MAOIs), one of the oldest yet most effective classes of antidepressants. We discuss how MAOIs such as phenelzine, tranylcypromine, isocarboxazid, and selegiline work by increasing serotonin, norepinephrine, and dopamine levels in the brain. The episode reviews their unique role in treatment-resistant and atypical depression, key adverse effects, important dietary considerations involving tyramine-containing foods, and potentially serious drug interactions. We also highlight practical clinical pearls to help pharmacists and healthcare professionals safely and effectively use these powerful but often underutilized medications.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Insomnia Medications – 6.2 Nursing Pharmacology Review Course
I cover the most important insomnia medications. We cover adverse effects, drug monitoring, and much more. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat …
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I cover the most important insomnia medications. We cover adverse effects, drug monitoring, and much more.
You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com!
Antidepressants: Trazodone, Nefazodone, Vilazodone, and Vortioxetine – Test Prep and Practice Pearls
In this episode, we explore four unique antidepressants that do not fit neatly into the traditional SSRI or SNRI categories: trazodone, nefazodone, vilazodone, and vortioxetine. Trazodone and nefazodone are …
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In this episode, we explore four unique antidepressants that do not fit neatly into the traditional SSRI or SNRI categories: trazodone, nefazodone, vilazodone, and vortioxetine. Trazodone and nefazodone are classified as serotonin antagonist and reuptake inhibitors (SARIs), working primarily through blockade of 5-HT2 receptors while also inhibiting serotonin reuptake. Trazodone’s strong antihistamine and alpha-1 blocking properties make it highly sedating and commonly used off-label for insomnia, whereas nefazodone causes less sedation but is rarely prescribed today because of its association with severe and potentially fatal liver toxicity. Both agents are notable for producing less sexual dysfunction than many traditional SSRIs.
We also discuss two newer multimodal antidepressants: vilazodone (Viibryd) and vortioxetine (Trintellix). Vilazodone combines serotonin reuptake inhibition with partial agonism at the 5-HT1A receptor, a mechanism often compared to combining an SSRI with buspirone. Vortioxetine has an even more complex pharmacology, acting as a serotonin reuptake inhibitor while modulating multiple serotonin receptor subtypes through agonist, partial agonist, and antagonist actions. This multimodal activity may contribute to benefits in cognitive symptoms associated with major depressive disorder. Throughout the episode, we compare receptor pharmacology, clinical applications, adverse effect profiles, and the unique characteristics that distinguish these medications from more commonly prescribed antidepressants.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
ICU Sedation – 6.1 Nursing Pharmacology Review Course
In this section, I educate about the most common ICU sedation medications. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and …
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In this section, I educate about the most common ICU sedation medications.
You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com!
SNRIs – Test Prep and Practice Pearls
Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressants that increase serotonin and norepinephrine levels in the brain. Common agents include venlafaxine (Effexor XR), desvenlafaxine …
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Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressants that increase serotonin and norepinephrine levels in the brain. Common agents include venlafaxine (Effexor XR), desvenlafaxine (Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), and milnacipran (Savella). In addition to treating depression and anxiety disorders, several SNRIs have important pain indications, making them especially useful in patients with neuropathy, fibromyalgia, or chronic musculoskeletal pain. Common adverse effects include nausea, sweating, insomnia, sexual dysfunction, and elevated blood pressure. Clinicians should also remember the significant discontinuation risk associated with shorter half-life agents like venlafaxine and desvenlafaxine.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Infectious Disease Section 5.4 – HIV Medications
Human Immunodeficiency Virus, or HIV, remains one of the most important infectious diseases in modern healthcare, but advances in antiretroviral therapy have transformed it from a fatal diagnosis into a …
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Human Immunodeficiency Virus, or HIV, remains one of the most important infectious diseases in modern healthcare, but advances in antiretroviral therapy have transformed it from a fatal diagnosis into a manageable chronic condition for many patients. In this episode, we’ll break down the major medication classes used to treat HIV, discuss how these drugs work, review key adverse effects and drug interactions, and highlight practical nursing considerations that impact patient safety and adherence. Whether you work in acute care, outpatient practice, long-term care, or public health, understanding HIV pharmacology is essential to providing compassionate, evidence-based care for patients living with HIV and AIDS.
You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com!
Mirtazapine and Bupropion – Test Prep and Practice Pearls
Mirtazapine is a unique antidepressant often chosen when depression occurs alongside insomnia or poor appetite. Its antihistamine activity makes it sedating, particularly at lower doses, and it commonly …
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Mirtazapine is a unique antidepressant often chosen when depression occurs alongside insomnia or poor appetite. Its antihistamine activity makes it sedating, particularly at lower doses, and it commonly increases appetite and weight. Unlike many SSRIs, mirtazapine has a lower risk of sexual dysfunction and gastrointestinal side effects because it blocks 5-HT2 and 5-HT3 receptors. It is frequently dosed at bedtime and can be especially useful in older adults or medically ill patients who need both mood improvement and help with sleep or weight gain.
Bupropion is an activating antidepressant that works by increasing norepinephrine and dopamine activity rather than serotonin. It is often preferred in patients with fatigue, low motivation, hypersomnia, or concerns about sexual dysfunction and weight gain. Bupropion is also approved for smoking cessation. Common adverse effects include insomnia, anxiety, dry mouth, and headache. A major clinical pearl is its dose-related seizure risk, making it contraindicated in patients with seizure disorders or eating disorders such as anorexia nervosa or bulimia.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Infectious Disease Section 5.3- Antifungal Agents
Fungal infections are commonly encountered across healthcare settings, ranging from oral thrush and vaginal yeast infections to serious systemic infections in critically ill patients. In this episode, we’ll …
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Fungal infections are commonly encountered across healthcare settings, ranging from oral thrush and vaginal yeast infections to serious systemic infections in critically ill patients. In this episode, we’ll review the major antifungal medications nurses should know, including azoles, echinocandins, polyenes, and topical antifungals. We’ll focus on practical nursing considerations such as monitoring for adverse effects, recognizing important drug interactions, administration tips, and patient education points. By the end of the episode, listeners will have a stronger understanding of how antifungal medications work and how nurses play a key role in ensuring safe and effective treatment.
You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com!
Tricyclic Antidepressants – Test Prep and Practice Pearls
Welcome to today’s episode on the tricyclic antidepressants, commonly known as TCAs — one of the foundational medication classes in psychopharmacology. Although newer antidepressants like SSRIs often dominate …
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Welcome to today’s episode on the tricyclic antidepressants, commonly known as TCAs — one of the foundational medication classes in psychopharmacology. Although newer antidepressants like SSRIs often dominate modern prescribing, TCAs remain highly relevant in clinical practice because of their effectiveness in treatment-resistant depression, chronic pain syndromes, migraine prevention, insomnia, and certain anxiety disorders. In this episode, we’ll break down the pharmacology behind these medications, discuss how tertiary amines differ from secondary amines, review major adverse effects and drug interactions, and highlight the key clinical pearls that healthcare professionals and students need to know. Whether you’re a medical, pharmacy, nursing, or PA student preparing for exams, or a practicing clinician looking for a practical refresher, this episode will give you a solid framework for understanding this classic but still clinically important medication class.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
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Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Infectious Disease Section 5.2- Antiviral Agents
This nursing pharmacology review covers the essential antiviral medications commonly encountered in clinical practice and on nursing exams. The video explains how antiviral drugs work, what infections they …
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This nursing pharmacology review covers the essential antiviral medications commonly encountered in clinical practice and on nursing exams. The video explains how antiviral drugs work, what infections they treat, and the key nursing considerations for safe medication administration and monitoring. Major medications discussed may include acyclovir, valacyclovir, oseltamivir, antiretroviral therapy, and other commonly prescribed agents.
You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com!
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