The Builders: Dario & Daniela Amodei

We're excited to share the third episode of The Builders. 

In this series, bestselling biographer Walter Isaacson sits down with the most consequential names in AI and tech to understand the futures they're racing to build. 

TechStuff listeners will want to tune in because on Friday, we'll discuss the 3rd and 4th episodes of The Builders and hear from journalists who've covered these personalities for years.

Dario and Daniela Amodei, the siblings behind Anthropic, left OpenAI to pursue a different, “more human” approach to the technology. Their promise is to put safety and ethics at the center of the tech race… but with an IPO around the corner, can those principles survive the pressure to win? 

Walter invites the co-founders to explain how they teach Claude right from wrong, what they’ve discovered about AI’s capacity for deception and self-preservation, and why they drew red lines with the Pentagon. Plus, the co-founders talk about Neuralink and why they’re not interested in integrating AI into their minds. 

Interview taped July 6, 2026.

And be sure to pick up Walter Isaacson’s The Innovators: How a Group of Hackers, Geniuses, and Geeks Created the Digital Revolution, wherever fine books are sold.

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