
#476 - Does NIPPV Work or Is It Just Higher Mean Airway Pressure?
Shownotes
Dr. Brett Manley joins Ben for the opening episode of The Incubator’s special series on non-invasive ventilation, recorded ahead of Hot Topics in Neonatology. They work through the full arc of non-invasive support, from the delivery room to the convalescent phase and beyond. What actually counts as nasal high flow, and when should it come off? Why did HIPSTER and HUNTER move clinicians back toward CPAP as primary support? Is the benefit of NIPPV about synchronization or simply higher mean airway pressure? Brett shares his own weaning approach, the ÉCLAT findings, and the trials he believes the field needs next.
This series is produced in partnership with Hot Topics in Neonatology and Fisher & Paykel Healthcare.
Join us at Hot Topics in Neonatology: National Harbor, MD, December 6 to 9, 2026. Register here: https://hottopicsinneonatology.nemours.org/registration.html
Don’t miss the live session continuing this conversation: Pressure, Flow, and the Grey Areas In Between. Presented by Fisher & Paykel Healthcare. Monday, December 7 at 11:45 AM. Full agenda: https://hottopicsinneonatology.nemours.org/agenda.html
As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.
Enjoy!