TWiV 1366: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are crestfallen to learn of the 6th measles death in Pennsylvania and more than 9000 deaths from Ebola, an enterovirus/Coxsackievirus outbreak at the University of Pennsylvania, decimation of the HIV services following withdrawal of PEPFAR and USAID, role of gut microbes in vaccine adverse events such as fever, continued raw milk consumption, and thermostable nanoparticles for mRNA vaccine delivery before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, measles, development of a rapid diagnostic for measles, how long COVID effects sleep cycles and the microbiome, and contacting your federal government representative to stop the assault on science and biomedical research.

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Links for this episode

• Hand, foot, and mouth disease cases spike at Penn this fall (The Daily Pennsylvanian)
• HIV service delivery after the PEPFAR and USAID HIV funding withdrawal in Uganda and Zimbabwe: an interrupted time-series study (LANCET: Global Health)
• The human gut microbiome primes fever after vaccination (Science)
• Escape to 11,100' in Rustic Luxury (HaydenBackcountry)
• Consumption of Unpasteurized (Raw) Milk and Milk Products by Pregnant People and Children: Policy Statement (Pediatrics)
• Raw milk poses serious infection risks with no added health benefits, pediatrician group warns (CIDRAP)
• The Science and the Stakes of Raw Milk Consumption with Pam Ruegg, Nicole Martin, and Daniel Griffin (Dairy Digressions)
• First Birth Cohort Eligible for Chickenpox Vaccine Had a Sharp Drop in Shingles Cases (Epic Research)
• Accelerated discovery of thermostable mRNA–lipid nanoparticle vaccines using data-efficient AI (Nature: Biotechnology)
• Legionnaires' Disease (NYC: Health)
• Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service)
• CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom)
• Ebola DRC (X)
• Ebola dashboard (ebola.fyi)
• EBOLA: The Democratic Republic of the Congo, 2026 (WHO)
• Bundibugyo virus disease outbreak Democratic Republic of the Congo(WHO: Democratic Republic of Congo)
• Ebola Outbreak: Current Situation (CDC:Ebola)
• Congo's Ebola infections surpass 9,000, government report shows (Reuters)
• I've Worked in Congo for Decades. I've Never Seen an Ebola Crisis Like This (NY Times)
• Pennsylvania reports its 6th measles death, in a Franklin County resident (CIDRAP)
• Subacute Sclerosing Panencephalitis after Measles Outbreaks, the Philippines, 2007–2022 (CDC: Emerging Infectious Diseases)
• Measles Outbreak in Amish Country Forces Some to Rethink Vaccines (NY Times)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Measles (VDH: Virginia Department of Health)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• HAP's Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania)
• Measles (Commonwealth of Pennsylvania)
• Measles Dashboard (New York State: Department of Health)
• Made in Africa: New measles rapid diagnostic tests mark breakthrough for vaccination efforts (GAVI: The Vaccine Alliance)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Measles Cases and Outbreaks (CDC: Rubeola)
• Laboratory Testing for Measles (CDC: Measles (Rubeola)
• Measles Clinical Diagnosis Fact Sheet (CDC: Measles (Rubeola)
• Measles Serology Testing (CDC: Measles (Rubeola)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• RSV Immunization Effectiveness and Safety for the 2026-2027 Respiratory Season (JAMA)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Moderna Receives U.S. FDA Approval for Updated 2026-2027 COVID-19 Vaccines (Moderna)
• Novavax's Partnership Strategy Continues to Deliver with XFG-adapted Nuvaxovid™ Approvals in the U.S., EU and Japan for 2026-2027 Vaccination Season (novavax)
• Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine (Pfizer)
• FDA approves new COVID vaccines (CIDRAP)
• Coronavirus Disease 2019 (COVID-19) Hospitalization Surveillance Network (COVID-NET)(CDC: Covid)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Characterizing sleep disturbance phenotypes in long COVID: an EHR-based study from a safety-net hospital (Academia Medicine and Health)
• Sputum and oral microbiota profiles are associated with long COVID severity and phenotype post-hospitalisation: a UK multicentre, prospective cohort study (European Respiratory Journal)
• Microtesla magnetic therapy for cognitive impairment in long COVID: a randomized pilot study (Brian Communications)
• Reaching out to US house representative
• Letters read on TWiV 1366
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

Content in this podcast should not be construed as medical advice.