TWiV 1361: Ancient Viral Sword and Shield

TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a host defense response to microbial infection in the brain.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker

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Links for this episode

• Support science education at MicrobeTV
• Bob Tesh dies (Galv News)
• Comment on propsed changes to NIH peer review (NIH)
• NIH peer review proposed changes (Forbes)
• Ancient RNA guided DNA recognition (Science)
• Noncontiguous geometric triplex (Science)
• p-tau has anti-herpes virus activity (Nat Neurosci)
• Letters read on TWiV 1361
• Timestamps by Jolene Ramsey. Thanks!

Picks of the Week

Brianne – APoD September 14: Origins of Elements Alan – Redshirts, by John Scalzi Vincent – Prone to Bruise by David Molesky he’s at Spring/Break till 9/28

Listener Pick

Anne – Nikon Small World in Motion Competition

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.