This Week in Dermatology — Jun 13, 2026

Welcome to This Week in Dermatology. This week we're covering 7 notable papers spanning the rise and real-world performance of artificial intelligence, new approaches to prognostication in inflammatory disease and skin cancer, and the complex landscape of genodermatoses from molecular mechanisms to patient counseling. Let's dive in. We begin with a major theme this week: artificial intelligence.

This week's papers:

1. General-purpose large language models outperform specialized clinical AI tools on medical benchmarks.. Nature medicine 2026
2. An ITGB4 variant modifies the severity of ITGA3-associated interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa (ILNEB).. The Journal of investigative dermatology 2026
3. Expanding histopathological assessment may provide limited prognostic value for metastatic cutaneous squamous cell carcinoma: insights from two nationwide nested case-control studies.. The British journal of dermatology 2026
4. Effectiveness and safety of hematoporphyrin monomethyl ether-mediated photodynamic therapy versus pulsed dye laser for port-wine stain: a retrospective study.. Journal of the American Academy of Dermatology 2026
5. Microdialysis-based metabolomic and proteomic profiling reveals signature variations for disease severity in psoriasis.. The Journal of investigative dermatology 2026
6. Artificial intelligence in dermatology: Clinical promise and environmental impact.. The Journal of investigative dermatology 2026
7. Patient Perspectives, Unmet Needs and Dilemmas in Reproductive Decision-making for Genodermatoses: A Qualitative Interview Study.. Acta dermato-venereologica 2026

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