PT 648 - Enamory - Couples Therapy with Ketamine

Enamory is a clinical practice, training institute, and nonprofit research organization focused on psychedelic assisted couples therapy. In this episode, clinical psychologists Chandra Kian and Kayla Knopp discuss their work integrating ketamine assisted psychotherapy with evidence based couples therapy models.

Both guests trained as academic researchers at the University of California San Diego Veterans Affairs system, where they worked on large scale couples based PTSD trials. They later co founded Enamory to continue clinical work, train therapists, and conduct research focused specifically on relationships.

Early Themes in Enamory and Couples Therapy

The conversation begins with Dr. Kian and Dr. Knopp describing their background in couples based PTSD research and how that work shaped their clinical approach.

They explain how existing couples therapy models often stall when partners cannot soften, access vulnerability, or understand each other's internal experience. Their early exposure to MDMA assisted therapy research highlighted how psychedelic states can temporarily reduce defensiveness and rigid narratives.