The Proof with Simon Hill
- Episódios
- 440
- Publicação
- semanal
- Último episódio
- 9 nov 2026
Sobre o podcast
The Proof Podcast is a space for science-based conversation. Together with his guests, Simon Hill, a qualified physiotherapist and nutritionist, explores the health and longevity benefits that come with mastering physical exercise, nutrition, mindfulness, recovery, sleep, and alignment. Facts, nuance and trustworthy recommendations minus the hyperbole. All the proof you need to live better for longer.
Episódios 440
How Much Muscle Can You Build Naturally? | Dr Eric Helms
This week I'm joined by Dr Eric Helms, a sports scientist, coach, and WNBF pro natural bodybuilder with more than 20 years of drug-free training behind him. He co-founded MASS Research Review and co-directs the …
Notas do episódio
This week I'm joined by Dr Eric Helms, a sports scientist, coach, and WNBF pro natural bodybuilder with more than 20 years of drug-free training behind him. He co-founded MASS Research Review and co-directs the Sports Research Institute New Zealand at the Auckland University of Technology.
Most lifters who stall assume they have hit their genetic limit. Eric explains why that is rarely the case, why gains diminish the longer you train, and how to decide what progress is actually worth to you.
What we cover
- Why a genetic ceiling is not a single fixed number
- How much progress is realistic after the beginner years
- Why women and men gain muscle at similar relative rates
- What steroid use does and does not leave behind
- How many sets, reps, and how close to failure suit busy lifters in their 40s and 50s
- Supersets, drop sets, and tracking your own training
If you want a more honest framework for your training, this one is for you. If you enjoy the show, a rating or review on Apple Podcasts goes a long way.
To connect with Dr Eric Helms, visit MASS Research Review or Muscle and Strength Pyramids, and follow him on Instagram. You can also listen to his podcast, Iron Culture.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Function Health
Make knowing your health part of your holiday plans. Function gives you access to 160+ lab tests for $365 a year - about a dollar a day. Join at functionhealth.com/SIMONHILL and use code SIMON25 for a $25 credit.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
LMNT
Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked.
LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
Shokz
Shokz OpenFit Pro brings Open-Ear Noise Reduction to open-ear listening, so background noise feels farther away while you stay connected to your surroundings. Head to shokz.com/THEPROOF and use code THEPROOF for a long-term discount on all Shokz products, stackable with other official promotions.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Treating Obesity Is Treating the Brain | Dr Elizabeth Kazarian
Elizabeth Kazarian is a physician double board-certified in Family Medicine and Obesity Medicine, practising in Washington DC. She treats obesity for a living, which means she spends as much time on insurance …
Notas do episódio
Elizabeth Kazarian is a physician double board-certified in Family Medicine and Obesity Medicine, practising in Washington DC. She treats obesity for a living, which means she spends as much time on insurance appeals as she does on clinical decisions.
Roughly one in ten American adults now reports using a GLP-1 medication, and the public conversation has split between people calling them a shortcut and people calling them a miracle. Elizabeth occupies the far more useful middle ground, and she is candid about where the evidence is strong, where it is thin, and where the real obstacles lie.
What We Cover
- Why treating obesity means treating the brain, and what that does to the willpower argument
- Why she stopped asking patients to earn medication through failed dieting
- What happens when people come off these drugs, including the part of the data nobody quotes
- The insurance and rebate machinery that decides which GLP-1 you are offered
- BMI, body composition, and working with a tool whose sensitivity is under 50%
- Menopause, PCOS, and fertility on and off these medications
- Her case that family medicine is the original longevity medicine
This is a clear-eyed look at what obesity medicine actually involves once you get past the injection. If you have found this topic more confusing each year, this conversation should help.
You can follow Dr Elizabeth Kazarian's work on Instagram, where she shares evidence-based education on obesity medicine, GLP-1 therapies, and women's cardiometabolic health.
If you enjoy the show, please leave a rating and review on Apple Podcasts. It helps new listeners find us.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Shokz
Shokz OpenFit Pro brings Open-Ear Noise Reduction to open-ear listening, so background noise feels farther away while you stay connected to your surroundings. Head to shokz.com/THEPROOF and use code THEPROOF for a long-term discount on all Shokz products, stackable with other official promotions.
Gusto
Gusto is online payroll and benefits software built for small businesses, handling payroll, tax filing, benefits, and onboarding in one place. Try Gusto today at gusto.com/THEPROOF and get three months free when you run your first payroll.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get $20 off your first order with code THEPROOF.
Function Health
Make knowing your health part of your holiday plans. Function gives you access to 160+ lab tests for $365 a year—about a dollar a day. Join at functionhealth.com/SIMONHILL and use code SIMON25 for a $25 credit.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Most 'Probiotic' Foods Aren't Actually Probiotic | Dr Maria Marco
The word gut health is on almost everything now, from yoghurt lids to supplement labels. So I asked food microbiologist Dr Maria Marco, Professor at UC Davis and President of the International Scientific …
Notas do episódio
The word gut health is on almost everything now, from yoghurt lids to supplement labels. So I asked food microbiologist Dr Maria Marco, Professor at UC Davis and President of the International Scientific Association for Probiotics and Prebiotics, what it actually means. She spent a year with a panel of clinicians, dieticians, and immunologists trying to define it, and the most striking finding was how much we still cannot measure.
This is a conversation about the distance between the science and the marketing, and it includes some claims that will change how you read a label.
What we cover
- The consensus definition of gut health, and why symptoms and pathology can point in opposite directions
- Whether commercial microbiome stool tests and diversity scores mean anything clinically
- Why sauerkraut sold as probiotic is, in Maria's words, "just a marketing thing"
- Whether the microbes in yoghurt survive digestion, colonise your gut, or simply pass through
- Why dead and pasteurised microbes may still be beneficial
- How to choose a probiotic that has actually been tested in people, and when to stop taking one
Maria is unusually willing to say what we do not yet know, and in a field this commercially crowded, that honesty is worth a great deal.
To connect with Dr Maria Marco, visit the Marco Lab at UC Davis, find her on LinkedIn, or follow her lab's work on Instagram at @eat.lac.project.
If this episode was useful, please leave a rating and review on Apple Podcasts or Spotify. It genuinely helps more people find the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
LMNT
Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked.
LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
What Bone Density Scans Can't Tell You About Fracture Risk | A Masterclass on Bone Health
In this masterclass, I bring together six experts to untangle bone health, from fracture risk and DEXA scans to strength training, joint pain, and surgery. Dr Lora Giangregorio, Prof Belinda Beck, Dr Deborah …
Notas do episódio
In this masterclass, I bring together six experts to untangle bone health, from fracture risk and DEXA scans to strength training, joint pain, and surgery. Dr Lora Giangregorio, Prof Belinda Beck, Dr Deborah Kado, Dr Howard Luks, Dr Lauren Colenso-Semple, and Dr Alyssa Olenick each add a different perspective.
Bone density is only one part of the fracture story, and the advice around lifting heavy often runs ahead of the evidence. Together, we turn the confusion into a practical framework.
What we cover:
- Why bone density is only one piece of fracture risk
- What DEXA cannot see, and why bone shape matters
- Whether you really need to lift heavy for your bones
- A bare minimum strength program for beginners
- When surgery helps, and why "bone on bone" is an unhelpful phrase
- How to build movement into everyday life
The best program is the one you can sustain, and I hope this gives you the confidence to start.
To connect with our guests, you can find Dr Lora Giangregorio on TikTok, X, and LinkedIn, or learn more through her University of Waterloo profile. Prof Belinda Beck can be found through The Bone Clinic, ONERO, her Griffith University profile, and Facebook. Dr Deborah Kado has a Stanford profile and is on LinkedIn. Dr Howard Luks writes on Substack and is on X and Instagram. Dr Lauren Colenso-Semple is on Instagram and at drlaurencs.com, and Dr Alyssa Olenick is on Instagram and YouTube, with her programs at doclyssfitness.com.
If you enjoyed this episode, please rate and review The Proof on Apple Podcasts and share it with someone who would find it useful.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
ProLon
ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF.
ProLon ships within the United States.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
Upwork
Post your job for free at Upwork.com and connect with top talent ready to help your business grow. Find the right talent to support your business and bring your projects to life.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
The Keto Study That Wasn't About Keto | Dr Nicola Guess
Practising registered dietitian and senior research fellow at the University of Oxford, Dr Nicola Guess, returns to the show to discuss a new study whose findings were interpreted in quite different ways the …
Notas do episódio
Practising registered dietitian and senior research fellow at the University of Oxford, Dr Nicola Guess, returns to the show to discuss a new study whose findings were interpreted in quite different ways the week it came out. Dr Samuel Klein’s group at Washington University assigned people with prediabetes to one of three diets, carefully controlled their weight loss, and found that the arm labelled ketogenic reduced liver fat by 67%.
Nicola’s view is that the label, and the conclusion many drew from it, deserve a closer look. Ketone levels in that arm were lower than you would typically expect on a ketogenic diet, which suggests something other than ketosis may explain the result. Her reading is that protein intake, rather than carbohydrate restriction, could be the more important variable. With roughly one in three adults carrying excess fat in the liver, often without symptoms, understanding what actually drives that reduction matters for the advice people receive.
What We Cover
- Why this trial should not have been called a ketogenic diet study
- How protein appears to lower liver fat even in the absence of weight loss
- The 23% saturated fat arm, and why ApoB fell anyway
- What likely changes once people move from weight loss into maintenance
- Whether liver fat causes insulin resistance or simply marks it
- Nicola's 35 grams of protein per meal target and how she builds a plate around it
- Where seed oils and fibre actually sit in the evidence
This is a good example of why the label on a study matters as much as its headline number. If you have been told to cut carbohydrates to fix your liver, this conversation is worth your time.
To connect with Nicola Guess, visit NicolaGuess.com or find her on Instagram and YouTube.
If you enjoy the show, please leave a rating and review on Apple Podcasts. It helps new listeners find us.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Eight Sleep
Upgrade your sleep with the Pod 6 by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $200 off. You get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
30 Years of Diet Trials: What a Stanford Scientist Is Most (and Least) Sure About | Dr Christopher Gardner
This is Christopher Gardner's eighth appearance on the show. Christopher is a nutrition scientist at Stanford, director of the Stanford Nutrition Studies Research Group, and the author of a new book, Food …
Notas do episódio
This is Christopher Gardner's eighth appearance on the show. Christopher is a nutrition scientist at Stanford, director of the Stanford Nutrition Studies Research Group, and the author of a new book, Food Sense: What to Eat and Why. He has run more than 20 human diet trials over three decades.
Instead of relitigating the diet wars, we spend this conversation on the machinery underneath them: the trade-off between rigour and real life, why the definitive trial people keep waiting for will never be run, and what a null result is actually worth. I also put a few recent studies to him that cut against my own position.
What we cover
- Why the perfect diet trial will never happen, and how that should change the way we read the evidence
- The $1.4 million garlic study that found nothing, and why Christopher is proud of it
- The four things every popular diet agrees on, and the six foods that divide them
- His keto versus Mediterranean trial, and the two findings that went in opposite directions
- How he approaches a new study that contradicts his own position
- Why he is shifting his focus to hospital, university, and military kitchens
If you take one thing from this episode, let it be the habit of asking what a finding can actually carry before you change anything.
To connect with Christopher Gardner, visit the Stanford Nutrition Studies Research Group, pick up a copy of Food Sense: What to Eat and Why, or find him on Instagram and LinkedIn.
If this episode was useful, a rating and review on Apple Podcasts genuinely helps more people find the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for your one-dollar-per-month trial at shopify.com/proof.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
My Plaque Protocol, and Why I Started a PCSK9 Inhibitor | Simon Hill, MSc
A few weeks ago I published my own heart scans, and one number travelled further than the rest: a 48% drop in plaque over 16 and a half months. The question underneath that video was the obvious one. How? This …
Notas do episódio
A few weeks ago I published my own heart scans, and one number travelled further than the rest: a 48% drop in plaque over 16 and a half months. The question underneath that video was the obvious one. How? This episode is the answer, and it is also the part I could easily have left out.
Three companies analysed the same two scans. HeartFlow found a 48% reduction, Cleerly found a 20% increase, and QAngio found essentially no change at all. Same heart, same images, and a sixfold spread in the absolute amount of plaque they measured. I walk through my full protocol, explain which analysis I anchor to and why, and tell you why, despite that headline, I have started a PCSK9 inhibitor.
What We Cover:
- Why cumulative ApoB exposure matters more than the cholesterol reading you have today
- My nutrition, training, and sleep protocol, and the supplements I deliberately avoided
- Why three platforms measuring the same heart came back with 11.5, 60, and 74 cubic millimetres
- The published concern about AI overestimation of plaque, and which analysis Dr Matthew Budoff trusts
- How my percentile swings 25 points depending on the reference database
- Why I started a PCSK9 inhibitor, and how I chose it over a statin
- Why you should be sceptical of dramatic short-interval scan results, including mine
All three analyses agreed on the thing that matters: the plaque burden is low, and it is not progressing rapidly. That agreement is worth far more than the headline.
Enjoyed this episode? A rating and review on the Apple Podcast app helps more people find the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Eight Sleep
Upgrade your sleep with the Pod 6 by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $200 off. You get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Upwork
Post your job for free at Upwork.com and connect with top talent ready to help your business grow. Find the right talent to support your business and bring your projects to life.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Why Your MRI Doesn't Mean You Need Surgery | Dr Howard Luks
Howard Luks is an orthopaedic surgeon with almost 30 years of experience, and a good deal of his week is spent telling people they do not need an operation. We work through the joints that bring most people …
Notas do episódio
Howard Luks is an orthopaedic surgeon with almost 30 years of experience, and a good deal of his week is spent telling people they do not need an operation. We work through the joints that bring most people into a clinic, knees, shoulders, Achilles tendons and ankles, and separate what a scan is actually telling you from what it is being used to justify.
Almost everyone over 40 has something on an MRI that will be described as a tear. Very few of those people need surgery, and plenty have no pain at all. Howard's case, drawn from three decades in clinic and the sham-surgery and physiotherapy-controlled trials behind it, is that our language has raced ahead of the biology, and that the words we use change how people move and live.
What We Cover
- Why "tear" and "bone on bone" are the wrong words, and what they do to a person's behaviour
- What sham surgery trials showed for meniscus tears, rotator cuff tears and bone spur removal
- How metabolic health shapes both your pain and your ability to heal after surgery
- Why tendons respond to load rather than rest
- Cortisone, PRP, stem cells and peptides: what the evidence supports and what is marketing
- Ice, anti-inflammatories and ankle sprains, and why early movement beats a boot
- Plyometrics, balance and power, and why they matter more than strength after 50
This is a conversation about being careful with language and honest about uncertainty, and about keeping your capacity so you can keep doing the things you care about.
To connect with Howard Luks, read his writing on Substack or find him on X and Instagram.
If you enjoy the show, please leave a rating and review on Apple Podcasts or Spotify. It genuinely helps other people find these conversations.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Eight Sleep
Upgrade your sleep with the Pod 6 by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $200 off. You get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Birth, Breastfeeding, and the Truth About Baby Food | Dr Federica Amati
This is part two of my conversation with Dr Federica Amati, Head Nutritionist at ZOE and author of the Sunday Times bestseller Every Body Should Know This. In part one we covered preconception, fertility, and …
Notas do episódio
This is part two of my conversation with Dr Federica Amati, Head Nutritionist at ZOE and author of the Sunday Times bestseller Every Body Should Know This. In part one we covered preconception, fertility, and pregnancy nutrition. Here we follow the first 1,000 days through to the end: birth, breastfeeding, weaning, and the environmental exposures behind all of it.
Much of this territory has become a source of guilt rather than clarity. Federica's framing is the one I keep returning to: this window is critical, but it is not fragile. Biology adapts, most of what shapes these years is structural, and where parents do have agency the evidence is more reassuring than the headlines suggest.
What we cover:
- Why a critical window is not a fragile one, and what the first 1,000 days actually set
- Choline, iodine, and omega-3 in pregnancy, and the "four eggs a day" myth
- C-sections and the infant microbiome, and why the differences largely converge by age two
- Breast milk as a living system, and an honest comparison with formula
- Weaning without the marketing: the smoosh test, iron at six months, and early allergen introduction
- Microplastics and endocrine disruptors, and the swaps that do the most work
Federica is exceptionally good at separating what the evidence supports from what the marketing claims, and she does it without ever making parents the villain.
To connect with Dr Federica Amati, follow her on Instagram at @dr.fede.amati or explore her work at ZOE. You can read more about the campaign she discusses in this episode at Plastic Free Babies, and her Sunday Times bestseller, Every Body Should Know This, is available wherever books are sold.
If this episode was useful, a rating or review on Apple Podcasts, or a follow on Spotify, makes a genuine difference to the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Upwork
Post your job for free at Upwork.com and connect with top talent ready to help your business grow. Find the right talent to support your business and bring your projects to life.
ProLon
ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF.
ProLon ships within the United States.
Skylight
Families are better when they’re working together. Right now, Skylight is offering our listeners $30 off their 15 inch Calendars by going to MySkylight.com/THEPROOF.
Skylight ships within the U.S. and to Canada, Australia, and the United Kingdom.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
The Liver Disease 30% of Us Have and Never Feel | Prof Aleksander Krag
Around 30% of the world's population has too much fat in their liver, and almost none of them know it. Liver disease stays silent until it is very advanced, which is exactly why so many people are found too …
Notas do episódio
Around 30% of the world's population has too much fat in their liver, and almost none of them know it. Liver disease stays silent until it is very advanced, which is exactly why so many people are found too late.
In this episode I sit down with Prof Aleksander Krag, professor and department chair of gastroenterology and hepatology at Odense University Hospital and former Secretary General of the European Association for the Study of the Liver, to separate the frightening headline number from the thing that actually determines risk. It is not the fat. It is the scarring, and there is a simple test that can tell you whether you have any.
What we cover
- Why a third of us have fat in our liver, and why that alone is not the thing to worry about
- Steatosis versus fibrosis, and why only scarring predicts clinical liver disease
- What blood-based alcohol biomarkers revealed about self-reported drinking
- The single home measurement that tracks liver risk best
- FIB-4, FibroScan, elastography, and ELF, explained plainly
- How reversible liver damage really is, and where semaglutide and resmetirom fit
- The policy levers Aleksander argues would prevent more disease than any clinic can
If you have ever wondered whether your drinking, your waistline, or your last set of liver enzymes is worth acting on, this conversation gives you a clear place to start.
To connect with Prof Aleksander Krag, visit the Centre for Liver Research (FLASH) at the University of Southern Denmark, follow him on X, or find him on LinkedIn.
If this episode was useful, please leave a rating and review on Apple Podcasts or Spotify. It genuinely helps more people find the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $350 off. You get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
The Case for Treating Cholesterol Before Plaque Appears | Dr Thomas Dayspring and Dr Dan Soffer
Almost all of us have atherosclerosis, and almost none of us are told so, because "normal" cholesterol is a population average rather than a physiological target. Dr Thomas Dayspring and Dr Dan Soffer, both …
Notas do episódio
Almost all of us have atherosclerosis, and almost none of us are told so, because "normal" cholesterol is a population average rather than a physiological target. Dr Thomas Dayspring and Dr Dan Soffer, both Masters of the National Lipid Association, join me for a conversation devoted entirely to primary prevention.
They do not agree on everything, and that is the point. Tom argues ApoB is the cause of atherosclerosis. Dan calls it the necessary substrate. Between them you get an unusually honest look at how two experienced clinicians weigh evidence, uncertainty, and their own bias when treating someone who feels perfectly well.
What We Cover:
- Why genes matter less for atherosclerosis than most people assume
- Is ApoB causal, or simply necessary? The disagreement, in full
- What "normal" cholesterol means, and the levels we are born with
- LDL-C years: a five-second calculation you can run on yourself
- What the 2026 dyslipidemia guideline changed
- How they would manage a healthy man in his thirties with a family history and an ApoB of 100
- Statin muscle symptoms, and the simple test that settles it
If you have ever been told your cholesterol is fine and wondered what that actually means, start here.
To connect with Dr Thomas Dayspring, find him on X, where he posts as @Drlipid. To connect with Dr Daniel Soffer, visit his Penn Medicine profile.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Skylight
Families are better when they’re working together. Right now, Skylight is offering our listeners $30 off their 15 inch Calendars by going to MySkylight.com/THEPROOF.
Skylight ships within the U.S. and to Canada, Australia, and the United Kingdom.
Pique
Pique’s Nandaka combines fermented Pu’er tea, full-spectrum Reishi, ceremonial cacao, and L-theanine for calm, sustained energy without the coffee crash. Unlock 20% off and establish your powerful foundation for sustained well-being at Piquelife.com/SIMON.
Pique ships within the U.S. and to Australia, Canada, and select EU countries.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for your one-dollar-per-month trial at shopify.com/proof.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Bone Health, Falls, Medications & Healthy Longevity | Dr Deborah Kado
Everyone wants to talk about longevity. Almost no one wants to talk about gerontology, the field that has been studying how to age well for a century. Dr Deborah Kado, Stanford professor of medicine and …
Notas do episódio
Everyone wants to talk about longevity. Almost no one wants to talk about gerontology, the field that has been studying how to age well for a century. Dr Deborah Kado, Stanford professor of medicine and geriatrician, joins me to bridge that gap.
From bone health and balance to deprescribing, gut microbiome research, and the surprising power of your attitude towards ageing, this is a masterclass in what actually matters for a long, well-lived life.
What We Cover:
- Why "longevity science" is largely gerontology rebranded
- A positive attitude towards ageing and its link to lower dementia risk
- Balance, power training, and preventing falls and fractures
- The truth about osteoporosis medications and the scare that drove millions away
- Why extra weight after menopause can be protective
- Vitamin D, sleep regularity, and the gut microbiome
This one will change how you think about growing older, whatever your age.
To connect with Dr Deborah Kado, visit her Stanford profile or find her on LinkedIn.
Enjoyed this episode? A rating and review on the Apple Podcast app helps more people find the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
ProLon
ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF.
ProLon ships within the United States.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Type 2 Diabetes Remission in the GLP-1 Era | Prof Roy Taylor
Professor Roy Taylor returns, three years after his first appearance, with the five-year DiRECT trial results and a clear-eyed assessment of where diet-driven type 2 diabetes remission stands in the GLP-1 era …
Notas do episódio
Professor Roy Taylor returns, three years after his first appearance, with the five-year DiRECT trial results and a clear-eyed assessment of where diet-driven type 2 diabetes remission stands in the GLP-1 era.
The evidence is now solid: type 2 diabetes is, for many, a reversible condition of excess fat in the liver and pancreas. But keeping it in remission demands keeping the weight off, and the new generation of weight loss drugs comes with marketing claims that Roy says have no evidence behind them.
What We Cover:
- The Twin Cycle Hypothesis and personal fat threshold
- Five-year DiRECT data: durable remission, halved hospital admissions, fewer cancers
- Why regaining the weight means the diabetes returns
- GLP-1s: what they genuinely do, and what's marketing
- The muscle loss panic, put in perspective
- Gestational diabetes and pre-pregnancy weight
Whether you have type 2 diabetes, care for someone who does, or simply want to understand one of the biggest shifts in modern medicine, this conversation delivers.
To learn more about Professor Roy Taylor's work, visit his research site at Newcastle University or read his book Life Without Diabetes. Clinicians can also explore his type 2 diabetes remission toolkit for general practice.
Enjoyed this episode? A rating and review on the Apple Podcast app helps more people find the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Upwork
Post your job for free at Upwork.com and connect with top talent ready to help your business grow. Find the right talent to support your business and bring your projects to life.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
HomeServe
Help protect your home systems – and your wallet – with HomeServe against covered repairs. Plans start at just $4.99 a month. Go to HomeServe.com to find the plan that’s right for you.
HomeServe is not available everywhere. Most plans range between $4.99 to $11.99 a month your first year. Terms apply on covered repairs.
Skylight
Families are better when they’re working together. Right now, Skylight is offering our listeners $30 off their 15 inch Calendars by going to MySkylight.com/THEPROOF.
Skylight ships within the U.S. and to Canada, Australia, and the United Kingdom.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Lowering Blood Sugar Without Weight Loss | Dr Nicola Guess
Can you meaningfully improve type 2 diabetes without losing weight? Dr Nicola Guess, registered dietitian and Senior Research Fellow at the University of Oxford, says the evidence is clear: a higher-protein …
Notas do episódio
Can you meaningfully improve type 2 diabetes without losing weight? Dr Nicola Guess, registered dietitian and Senior Research Fellow at the University of Oxford, says the evidence is clear: a higher-protein, lower-carbohydrate diet can lower post-meal glucose by more than medication, no weight loss required.
We also tackle the noisier end of the blood sugar conversation: glucose spikes, fruit fear, insulin-first theories of obesity, and the panic about GLP-1s and muscle loss.
What We Cover:
- Why glucose only causes direct harm at diabetic levels
- How protein wakes up "sleepy" beta cells
- What overfeeding trials reveal about insulin and obesity
- Fruit, fibre, and fat quality: what matters and what doesn't
- Menopause, PCOS, and shift work
- The truth about GLP-1s and muscle loss
If you want a clear-eyed guide to metabolic health without the hype, this episode delivers.
To connect with Dr Nicola Guess, visit nicolaguess.com or find her on Instagram and YouTube.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for your one-dollar-per-month trial at shopify.com/proof.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $350 off. You get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
The Fertility Test Most Men Are Never Offered | Dr Michael Eisenberg and Dr Natalie Crawford
About one in seven couples are unable to conceive after a year of trying, and roughly half of those cases involve a male contribution. Yet in a quarter to a third of them, the man is never properly evaluated …
Notas do episódio
About one in seven couples are unable to conceive after a year of trying, and roughly half of those cases involve a male contribution. Yet in a quarter to a third of them, the man is never properly evaluated. In this episode I sit down with Dr Michael Eisenberg, a urologist, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, and Dr Natalie Crawford, a reproductive endocrinologist and co-founder of Fora Fertility in Austin, Texas.
This is the comprehensive male fertility resource I went looking for and couldn't find, and I have a personal stake in it. What surprised me most is that sperm health appears to be about much more than conception. It tracks with metabolic health, immune health, pregnancy outcomes, and in one Danish cohort, with age of death decades later.
What We Cover
- What a semen analysis measures, and why ejaculating normally tells you nothing
- Semen quality as a sixth vital sign, and the Danish study linking it to lifespan
- Testosterone therapy, why it functions as a contraceptive, and how long recovery takes
- Whether sperm counts are really declining, and the likely drivers
- Cannabis, alcohol, heat, cycling, sleep, and body weight
- Total motile sperm count, DNA fragmentation, and what to ask your lab for
- Paternal age, sperm freezing, and timing your decisions
Sperm turn over roughly every three months, which makes this one of the most movable metrics in health. Whichever stage of life you're at, this conversation is worth your time.
To connect with Dr Michael Eisenberg, find him on Instagram or LinkedIn. To connect with Dr Natalie Crawford, you can find her book The Fertility Formula at nataliecrawfordmd.com/book, listen to her podcast As a Woman, or follow her on Instagram, TikTok, YouTube, and LinkedIn.
If this episode was useful, please leave a rating and review on Apple Podcasts. It genuinely helps more people find the show.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Pique
Pique’s Nandaka combines fermented Pu’er tea, full-spectrum Reishi, ceremonial cacao, and L-theanine for calm, sustained energy without the coffee crash. Unlock 20% off and establish your powerful foundation for sustained well-being at Piquelife.com/SIMON.
Pique ships within the U.S. and to Australia, Canada, and select EU countries.
Skylight
Families are better when they’re working together. Right now, Skylight is offering our listeners $30 off their 15 inch Calendars by going to MySkylight.com/THEPROOF.
Skylight ships within the U.S. and to Canada, Australia, and the United Kingdom.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Superagers, statins, the latest cholesterol pill and the truth about heart disease risk | Dr Terry Simpson
Dr Terry Simpson is back, and we go deep on the science of protecting your heart and brain for the long run. He is a surgeon and one of the clearest voices online for separating solid evidence from confident …
Notas do episódio
Dr Terry Simpson is back, and we go deep on the science of protecting your heart and brain for the long run. He is a surgeon and one of the clearest voices online for separating solid evidence from confident hype, and in this conversation we tackle everything from new cholesterol-lowering drugs to gene editing, cognitive ageing, and the lean mass hyperresponder debate.
Along the way we get a few things off our chests about the misinformation that spreads faster than the careful answer ever can.
What We Cover
- Why healthy ageing brains owe more to lifestyle than to genetics
- How PCSK9 inhibitors work, and why plaque is more like geology than plumbing
- Gene editing for cholesterol and functional cures for type 1 diabetes
- The lean mass hyperresponder debate and what the Keto-CTA re-analysis shows
- Why colorectal cancer is rising in younger adults
- The 2026 dyslipidemia guidelines and why you should test your Lp(a) once
This is a grounded, evidence-first conversation, and I hope it helps you feel clearer and more confident about the decisions that actually move the needle. If you enjoy the episode, please take a moment to rate and review the show, it genuinely helps more people find it.
To connect with Dr Terry Simpson, visit terrysimpson.com, where you will find his bio, recipes, and plenty more. You can also follow him on Instagram, X, and TikTok, and read his writing on Substack.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $350 off. You get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
LMNT
Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked.
LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
The Science of Metabolic Flexibility, Zone 2, and Reversing Diabetes | A Masterclass
Metabolic dysfunction rarely announces itself. We tend to think of metabolic health as a line you cross the day you are diagnosed with type 2 diabetes, but the decay usually begins years earlier, at the level …
Notas do episódio
Metabolic dysfunction rarely announces itself. We tend to think of metabolic health as a line you cross the day you are diagnosed with type 2 diabetes, but the decay usually begins years earlier, at the level of the cell. In this masterclass I bring together Dr Iñigo San Millán, Dr Alan Flanagan, Dr Kevin Hall, Dr Robert Eckel, Professor Roy Taylor, and Dr Christos Mantzoros to explain what metabolic flexibility is, why your mitochondria sit at the centre of it, and what you can actually do about it.
What We Cover
- Why lactate is a fuel and a signal, not a waste product, and our best non-invasive window into mitochondrial function
- Whether a calorie really is a calorie, and what the controlled chamber studies found
- The twin cycle hypothesis, and why type 2 diabetes is more reversible than we were taught
- The personal fat threshold, and why a normal BMI can still hide a problem
- Whether sugar or saturated fat does more to drive fat in the liver
- Why Zone 2 earns its reputation, and how much of it you actually need
Metabolic health is not fixed, and it is rarely too late to move in a better direction. I hope this conversation gives you a clearer picture of what is happening beneath the surface, and a few levers you can start pulling today.
To learn more from the experts featured in this masterclass, you can follow Dr Iñigo San Millán on Instagram and Twitter, explore Professor Roy Taylor's work on type 2 diabetes remission at Newcastle University, read more from Dr Kevin Hall at kevinhallphd.com or on LinkedIn, and find Dr Alan Flanagan on Instagram and through Alinea Nutrition. The masterclass also features insights from Dr Robert Eckel and Dr Christos Mantzoros.
If you are enjoying The Proof, please take a moment to rate and review the show on Apple Podcasts. It genuinely helps more people find these conversations.
- The 81-Year-Old Who Reversed 30 Years of Damage (00:00)
- What Metabolic Health Actually Means Now (01:57)
- Why Mitochondria Decide Your Disease Risk (06:01)
- What Is Metabolic Flexibility? (12:47)
- Hepatic Fat Oxidation and the Sex Difference (15:20)
- Is a Calorie Really a Calorie? (18:29)
- You Can Be Sick Before You're Diagnosed (28:41)
- Why Lactate Is the Biomarker to Watch (29:20)
- Lactate Is Not a Waste Product (31:03)
- Is Lactic Acid Burn a Myth? (36:42)
- Why Athletes Clear Lactate and You Don't (40:34)
- When High Lactate Predicts Death (43:01)
- The Study That Found Damage in Healthy People (47:13)
- The Lactate Test That Beats Blood Sugar (54:31)
- Training Zones 1 to 6 Explained by Fuel (58:50)
- Why Zone 2 Builds Mitochondria Best (1:09:18)
- How to Know You're in Zone 2 Without a Lab (1:16:50)
- Is 150 Minutes a Week Enough? (1:23:39)
- Why You Still Need High Intensity Training (1:28:10)
- What Obesity Research Got Wrong (1:31:44)
- The Twin Cycle Hypothesis of Type 2 Diabetes (1:35:04)
- Your Personal Fat Threshold Explained (1:42:26)
- Why Some People Store Fat Safely (1:45:45)
- Why BMI Fails as a Health Measure (1:51:29)
- Sugar or Saturated Fat: What Drives Liver Fat? (1:55:07)
- 15kg Weight Loss and Diabetes Remission (2:01:05)
- Does Weight Loss Really Destroy Muscle? (2:04:39)
- Why Exercise Alone Doesn't Drop Weight (2:07:05)
- 3 Tests That Reveal Your Metabolic Health (2:11:14)
- What Blue Zones Get Right About Movement (2:17:40)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
Truemed
Truemed helps qualified customers use pre-tax HSA or FSA dollars on health-related products like fitness, recovery, and sleep tools, often saving around 30% on average. Visit truemed.com/THEPROOF to see what qualifies. This is hands down the best way to make the most of your health dollars.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
New Science of Weight Loss | A Masterclass
GLP-1 medications are transforming obesity treatment, but they're only one piece of the puzzle. In this masterclass, I bring together insights from Dr Terry Simpson, Dr Federica Amati, Dr Mauricio Gonzalez, Dr …
Notas do episódio
GLP-1 medications are transforming obesity treatment, but they're only one piece of the puzzle. In this masterclass, I bring together insights from Dr Terry Simpson, Dr Federica Amati, Dr Mauricio Gonzalez, Dr Christos Mantzoros, and Dr Stephan Guyenet to explain how these medications work, why "food noise" matters, and what it really takes to improve long-term metabolic health.
What We Cover
- How GLP-1 medications regulate appetite and food noise
- Why obesity is more complex than willpower
- Semaglutide vs tirzepatide and newer medications
- Nutrition and resistance training while taking GLP-1s
- The role of fibre, protein, and Mediterranean-style eating
- Common misconceptions and side effects
I hope this episode helps you better understand both the promise and the limitations of GLP-1 medications, while highlighting the importance of lifestyle alongside any medical treatment.
- Why Terry Simpson Started Taking a GLP-1 (00:00)
- What Is Food Noise, Really? (04:59)
- Why GLP-1 Drugs Work So Well (10:16)
- What Actually Causes Obesity (17:37)
- How GLP-1 Medications Work in the Body (21:22)
- The Strange Lizard Behind GLP-1 Drugs (25:56)
- 3 Types of Hunger You Didn't Know About (28:41)
- How to Naturally Boost Fullness Signals (37:08)
- How Doctors Choose Which GLP-1 to Prescribe (45:10)
- Why Some People Don't Respond to GLP-1s (53:09)
- GLP-1 Side Effects, Guilt, and Eating Right (58:12)
- Mediterranean Diet's Effect on Long-Term Weight Loss (01:10:29)
- The Shame Around Taking GLP-1 Medications (01:20:00)
- Being Called a Pharma Shill (01:32:39)
- The History Behind GLP-1 Drugs (01:38:18)
- Will You Need GLP-1s Forever? (01:47:04)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $350 off. You get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
ProLon
ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF.
ProLon ships within the United States.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Fertility, Sperm Health, and Nutrition Before and During Pregnancy | Dr Federica Amati
We tend to treat pregnancy as the starting line for a child's health. In this episode, Dr Federica Amati, Head Nutritionist at ZOE, makes the evidence-based case that the window opens earlier, in the months …
Notas do episódio
We tend to treat pregnancy as the starting line for a child's health. In this episode, Dr Federica Amati, Head Nutritionist at ZOE, makes the evidence-based case that the window opens earlier, in the months before conception, and that it shapes fertility and lifelong health in ways most of us were never told.
What I valued most is her balance. The science is striking, but she frames it as information to act on rather than a reason for guilt, and she is honest about how much sits with environment and policy rather than individual choice.
What we cover:
- Why the first 1,000 days may be the longevity lever almost no one talks about
- How a father's metabolic health links to his child's brain, and a mother's to their metabolism
- The 90-day preconception window, and what both partners can do
- What the decline in sperm counts really means for individuals
- GLP-1 medications, fertility, and a contraception detail too few people hear
- Protein, eggs, soy, and choosing a prenatal supplement, myths included
Whether you are planning a pregnancy, supporting a partner, or simply curious about how much of our health is set before birth, I think this one will stay with you.
To connect with Dr Federica Amati, follow her on Instagram and explore her work at ZOE.
If you enjoy the show, please take a moment to rate and review The Proof on Apple Podcasts or Spotify. It genuinely helps more people find these conversations.
- Intro (00:00)
- Why Your Baby's Health Is Set Before Birth (03:13)
- Dr. Federica Amati's Background in Maternal Nutrition (07:41)
- What 48 of 52 Cell Differentiations Means for Your Baby (15:33)
- How Egg and Sperm Health Drive Conception Outcomes (21:40)
- Does What You Do Preconception Affect the Baby Too (26:09)
- Sperm DNA and Placental Health: The Father's Hidden Role (30:39)
- Heat, Laptops, and Sauna: What Kills Sperm Quality (32:56)
- Is the 50% Sperm Count Decline Real (39:32)
- Soy Foods, Testosterone, and Male Fertility Myths Debunked (44:30)
- Foods to Avoid in the 90-Day Preconception Window (48:10)
- GLP-1 Drugs, Fertility, and Unplanned Pregnancies (54:28)
- First Trimester Nausea: What Actually Helps (59:42)
- How to Choose a Prenatal Supplement (01:04:34)
- How Much Protein Do You Actually Need in Pregnancy (01:07:30)
- Can a Plant-Based Diet Work During Pregnancy (01:11:59)
- Tylenol in Pregnancy: Is It Safe (01:15:55)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
We'd love your feedback. Complete our quick 2-minute audience survey to help us better understand what content, topics, and guests you enjoy most. Take the survey at voicingchange.media/simon.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Pique
Pique’s Nandaka combines fermented Pu’er tea, full-spectrum Reishi, ceremonial cacao, and L-theanine for calm, sustained energy without the coffee crash. Unlock 20% off and establish your powerful foundation for sustained well-being at Piquelife.com/SIMON.
Pique ships within the U.S. and to Australia, Canada, and select EU countries.
Truemed
Truemed helps qualified customers use pre-tax HSA or FSA dollars on health-related products like fitness, recovery, and sleep tools, often saving around 30% on average. Visit truemed.com/THEPROOF to see what qualifies. This is hands down the best way to make the most of your health dollars.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Can You Reverse Heart Disease? What My Plaque Scans Showed | Dr Campbell Rogers
In late 2024 a CT scan revealed a small amount of soft plaque in my arteries. Sixteen months later I scanned again, and my plaque volume had dropped by around forty percent. In this episode I ask the …
Notas do episódio
In late 2024 a CT scan revealed a small amount of soft plaque in my arteries. Sixteen months later I scanned again, and my plaque volume had dropped by around forty percent. In this episode I ask the cardiologist behind the technology whether a result like that can really be trusted.
Dr Campbell Rogers is an interventional cardiologist, a former Harvard faculty member who ran the cath lab at Brigham and Women's Hospital, and now Chief Medical Officer at Heartflow.
What we cover:
- The difference between a calcium score, a CT coronary angiogram, and AI plaque analysis
- Why a calcium score of zero does not mean you are free of disease
- What my own scans showed, and why Campbell believes the result
- Soft versus calcified plaque, and why calcification can be a sign of stabilisation
- Treating the plaque you can see rather than just an ApoB number
- Who should consider getting scanned, and the honest trade-offs
This is a conversation about seeing a disease we used to only guess at, held with the right amount of scientific humility. If you want to understand your own heart health, I think it is well worth your time.
If you enjoy the show, please take a moment to rate and review The Proof on Apple Podcasts or Spotify. It genuinely helps more people find these conversations.
To connect with Dr Campbell Rogers, visit Heartflow.
- How Campbell Rogers went from cardiologist to Heartflow (00:00)
- What Heartflow is and how it works (07:26)
- Coronary CT angiogram vs. stress test (11:54)
- Why symptoms alone miss early heart disease (13:18)
- How Heartflow analyzes CT scans in 90 minutes (15:58)
- Calcified vs. non-calcified plaque: which is riskier (21:28)
- Why calcium score zero doesn't mean no heart disease (28:45)
- Who should get a CT angiogram with AI plaque analysis (31:09)
- Why seeing your plaque improves medication adherence (34:04)
- Simon's 2024 Heartflow scan results (39:12)
- How plaque rupture triggers a heart attack (43:25)
- Simon's 2026 Heartflow scan: 40% plaque reduction in 16 months (45:43)
- How long to wait between CT scans (51:14)
- Heartflow vs. Cleerly vs. QAngio (53:12)
- How Heartflow results led Simon to start statins (58:21)
- JAMA study: Heartflow tracks plaque in prostate cancer patients (1:00:10)
- What is low attenuation plaque and why it's high risk (1:02:53)
- Who should ask their doctor about a coronary CT angiogram (1:07:37)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
We'd love your feedback. Complete our quick 2-minute audience survey to help us better understand what content, topics, and guests you enjoy most. Take the survey at voicingchange.media/simon.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF at eightsleep.com/theproof for up to $500 off. The 4th of July sale ends July 12, and you get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
LMNT
Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked.
LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for your one-dollar-per-month trial at shopify.com/proof.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Reversing Artery Plaque: 8 Supplements Ranked by the Evidence | Simon Hill, MSc
Can a supplement actually reverse the plaque in your arteries, or only slow it down? It is the question I am asked most, and after a 2024 scan revealed early plaque in my own left anterior descending artery, it …
Notas do episódio
Can a supplement actually reverse the plaque in your arteries, or only slow it down? It is the question I am asked most, and after a 2024 scan revealed early plaque in my own left anterior descending artery, it became a personal one too.
This is part two of my three-part series on reversing atherosclerosis. In this solo episode I work through eight of the most popular supplements and rank them by the strength of the human evidence, not the strength of the marketing.
What we cover:
- Why pure EPA has by far the strongest evidence for regressing plaque, and what EVAPORATE, CHERRY, JELIS, and REDUCE-IT showed
- The REDUCE-IT versus STRENGTH debate, and why the form of omega-3 may matter as much as the dose
- Aged garlic extract and vitamin K2: what the imaging and calcification data suggest
- Niacin and the biomarker trap: raising "good" cholesterol without lowering risk
- Where CoQ10, berberine, nattokinase, and pomegranate extract really sit, plus a fact-check of a popular nattokinase claim
- My own plan after that scan, and a preview of part three on the pharmaceuticals
Only one of these eight has strong evidence behind it, and even then it is a prescription rather than a tub from the supplement aisle. Supplements can be useful additions, but never a replacement for the proven basics.
You can see exactly what I take over at my personal supplement stack.
If you are enjoying the series, the simplest way to help is to leave a quick rating and review on Apple Podcasts, and to share this episode with someone whose heart health you care about.
- Can Supplements Actually Reverse Arterial Plaque? (00:00)
- EVAPORATE Trial: High-Dose EPA Reversed Plaque by 9% (02:09)
- Why Pure EPA Outperforms Standard Fish Oil (07:22)
- JELIS to REDUCE-IT: EPA Cuts Cardiac Events by 25% (10:10)
- REDUCE-IT Controversy and RESPECT-EPA 2024 (13:47)
- VITAL Trial: Omega-3 for Healthy Adults + 2026 Lp(a) Data (16:51)
- Aged Garlic Extract: 3 Trials on Plaque and Calcification (20:09)
- Vitamin K2: Does Redirecting Calcium Lower Heart Risk? (23:17)
- Niacin Failed: Why Raising HDL Didn't Save Lives (27:50)
- CoQ10: Promising Mechanism, No Plaque Imaging Proof (33:18)
- Berberine: The Gut Pathway No Other Supplement Uses (38:21)
- Nattokinase: One Study Says 36% Drop, One Says Zero (41:16)
- Pomegranate Extract: Strong Animal Data, Weak Human Trials (49:16)
- Which Supplements Can Actually Reverse Atherosclerosis? (53:18)
- Simon's Personal Protocol for Reversing LAD Plaque (55:24)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
We'd love your feedback. Complete our quick 2-minute audience survey to help us better understand what content, topics, and guests you enjoy most. Take the survey at voicingchange.media/simon.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. 38Tera ships to the United States, Australia, and New Zealand.
LMNT
Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked.
LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
HomeServe
Help protect your home systems – and your wallet – with HomeServe against covered repairs. Plans start at just $4.99 a month. Go to HomeServe.com to find the plan that’s right for you.
HomeServe is not available everywhere. Most plans range between $4.99 to $11.99 a month your first year. Terms apply on covered repairs.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
How to Lose Weight and Fix Your Metabolism in 2026 | Dr Mauricio Gonzalez
For decades we have treated the number on the scale as the goal of metabolic health. Dr Mauricio Gonzalez, a triple board-certified physician and endocrinology fellow practising in New York, makes the case that …
Notas do episódio
For decades we have treated the number on the scale as the goal of metabolic health. Dr Mauricio Gonzalez, a triple board-certified physician and endocrinology fellow practising in New York, makes the case that we have been measuring the wrong thing.
In this conversation we explore why liver fat, not body weight, is becoming the real target, what the latest weight-loss medications can and cannot do, and how to cut through the hype and dogma that surround this field.
What we cover:
- Why isolated blood tests and blood pressure readings tell you very little
- The myth that GLP-1 medications are "the easy way out"
- Why liver fat may matter more than body weight
- How diabetes clinics now remove medications instead of adding them
- Which supplements earn their place, and which Mauricio has cooled on
- The minimum effective dose for exercise, and knowing when "enough" is enough
A grounded, practical conversation with a doctor who meets people where they are. If you enjoy the show, please take a moment to rate and review The Proof on Apple Podcasts or Spotify, it genuinely helps more people find these conversations.
To connect with Dr Mauricio Gonzalez, follow him on Instagram, X, and YouTube, or visit his website at drmauriciogonzalez.com.
- Intro (00:00)
- Minimum Effective Dose for Exercise (01:38)
- Why Continuity of Care Reduces Mortality (07:09)
- How Type 2 Diabetes Silently Develops Over 12 Years (09:23)
- Statin vs. PCSK9 Inhibitor: How Doctors Choose (12:45)
- How GLP-1 Drugs Transformed the Diabetes Clinic (21:46)
- Why Doctors Now Measure Organ Fat, Not Body Weight (30:25)
- How Fatty Liver Disease Is Diagnosed (34:05)
- How Liver Fat Drives Insulin Resistance (40:47)
- Wegovy vs. Zepbound: How to Choose a GLP-1 (48:18)
- Should Lean People Use GLP-1s for Metabolic Health? (51:53)
- Why Patients Feel Guilty Taking GLP-1s (54:13)
- How Mauricio’s Nutrition Advice Has Evolved Over a Decade (01:04:35)
- Supplements on GLP-1s: What's Worth Taking (01:09:42)
- Minimum Effective Dose for Resistance Training (01:16:52)
- When Health Optimization Becomes Counterproductive (01:21:20)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Use code THEPROOF at eightsleep.com/theproof for up to $500 off. The 4th of July sale ends July 12, and you get 30 days to try it at home and return it if you don't love it.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
Truemed
Truemed helps qualified customers use pre-tax HSA or FSA dollars on health-related products like fitness, recovery, and sleep tools, often saving around 30% on average. Visit truemed.com/THEPROOF to see what qualifies. This is hands down the best way to make the most of your health dollars.
ProLon
ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF.
ProLon ships within the United States.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Evidence-Based Exercise in Pregnancy and Postpartum | Dr Margie Davenport
In this episode, exercise physiologist Dr Margie Davenport walks me through what the evidence actually shows about exercise during pregnancy and the postpartum period. Margie chaired the 2019 Canadian Guideline …
Notas do episódio
In this episode, exercise physiologist Dr Margie Davenport walks me through what the evidence actually shows about exercise during pregnancy and the postpartum period. Margie chaired the 2019 Canadian Guideline for Physical Activity throughout Pregnancy, the 2025 Canadian postpartum guideline, and the upcoming International Olympic Committee consensus statement on athletes through pregnancy and postpartum.
We cover where the 140 bpm rule came from, the scale of the benefits at the population level, what direct fetal monitoring during HIIT and heavy lifting really shows, the new postpartum data, and why so many of the historical prohibitions do not survive contact with the data.
What we cover:
- Where the 1985 "stay below 140 bpm" rule came from, and why it has long outlived its evidence
- Around 40 percent fewer cases of preeclampsia and gestational diabetes, and around 67 percent fewer cases of depression during pregnancy
- HIIT, heavy resistance training, and what fetal monitoring shows
- The 51 percent reduction in complications among women who kept lifting heavy
- Postpartum: the six-week myth, breastfeeding and injury risk, and a 45 percent reduction in postpartum depression
- The short list of actual "don'ts": scuba diving, and a few situational cautions
- The paradigm shift from prohibition to shared decision-making
If this episode is useful, please leave a rating and review on Apple Podcasts or Spotify, and share it with someone in your life who is trying to make sense of conflicting advice.
To connect with Dr Margie Davenport, visit exerciseandpregnancy.ca, follow her on Instagram at @DrMargieDavenport, or find her on LinkedIn and YouTube.
- Intro (00:00)
- Why Pregnancy Exercise Advice Feels So Confusing (01:15)
- The Most Damaging Myth About Exercise In Pregnancy (03:08)
- How Exercise Cuts Pregnancy Complications By 40% (05:05)
- Why Pregnant Women Were Excluded From Research (07:46)
- Can You Do High Intensity Workouts While Pregnant (12:49)
- How Exercise Lowers Preeclampsia And Diabetes Risk (16:43)
- How Much Exercise Is Safe During Pregnancy (27:03)
- Is Heavy Lifting Safe During Pregnancy (32:10)
- What You Should Never Do While Pregnant (40:41)
- Pelvic Floor Exercises Every Pregnant Woman Needs (47:41)
- How To Know If You're Overexerting While Pregnant (56:12)
- Does Exercise Affect Fertility And Conception (1:00:42)
- Why The 140 BPM Myth Still Exists (1:04:52)
- How Exercise Improves Postpartum Mental Health And Sleep (1:09:28)
- The Truth About The 6 Week Postpartum Rule (1:11:32)
- Does Breastfeeding Increase Your Risk Of Injury (1:17:13)
- Why Pregnant Athletes Need Better Policy Support (1:19:56)
- What Future Pregnancy Exercise Research Will Reveal (1:24:50)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38TERA ships to the United States, Australia, and New Zealand.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
ProLon
ProLon’s 5-Day Fasting Mimicking Diet is a science-backed, plant-based program designed to support metabolic health while keeping your body in a fasting-like state. Get 15% off sitewide plus a $40 bonus gift at ProLonLife.com/THEPROOF.
ProLon ships within the United States.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
WHOOP
WHOOP, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
WHOOP ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Nutrition for satiety and weight loss | Dr Federica Amati
GLP-1 medications are now part of the mainstream conversation, but the biology of appetite and satiety, the system these drugs operate within, gets far less attention than the drugs themselves. In this episode …
Notas do episódio
GLP-1 medications are now part of the mainstream conversation, but the biology of appetite and satiety, the system these drugs operate within, gets far less attention than the drugs themselves. In this episode, I sit down with Dr Federica Amati, Head Nutritionist at ZOE and author of the new book The Appetite Reset, to explore what's actually happening in the gut and brain when appetite signals do their job, and what that means for everyone, on or off medication.
Federica brings a rare combination of pharmacology, clinical nutrition, and public health expertise to a subject that rarely receives this level of nuance. This is a conversation about understanding your biology well enough to work with it.
What we cover:
- How GLP-1 works naturally in the body, why the natural peptide lasts minutes while the drug version lasts days, and why this matters for anyone using or considering these medications
- The three types of hunger (hedonic, homeostatic, and microbiota-driven) and how to tell them apart in practice
- Why GLP-1 supplements don't replicate what the medications do
- "Prehab" before starting medication: gut microbiome diversity, fibre intake, and nutrient status as the foundation
- Why the 30g daily fibre target doesn't drop when calorie intake does on medication
- Protein targets of 1.2 to 1.6g per kilogram and resistance training three times a week as the most critical protective interventions for muscle and bone health
- The science on shame, weight stigma, and why treating obesity as a lifestyle choice is both inaccurate and actively harmful
If this episode was useful, a review on Apple Podcasts or a follow on Spotify makes a genuine difference.
To connect with Dr Federica Amati, follow her on Instagram at instagram.com/dr.fede.amati or explore her work through ZOE at zoe.com. Her new book, The Appetite Reset, will be released on June 25 and is available to pre-order now.
- Intro (00:00)
- Why Everyone Needs to Understand Appetite Biology (01:14)
- How Dr. Federica Amati Became a Nutrition Expert (03:06)
- Why GLP-1 Drugs Are Different From Any Supplement (11:29)
- The Gila Monster That Led to Ozempic (17:44)
- What Is Food Noise and Why It Controls You (20:20)
- Why Willpower Isn't the Problem: Genetics and Epigenetics (24:06)
- How GLP-1s Change Your Relationship With Food and Joy (30:54)
- Lowest Effective Dose: Why More Isn't Better (34:08)
- The Muscle Loss Risk Nobody Warns You About (39:34)
- Microdosing GLP-1s: Does It Work or Is It Dangerous (41:59)
- The Three Types of Hunger and How to Tell Them Apart (44:51)
- How Your Gut Microbes Drive Cravings and Leptin Resistance (50:17)
- Why Calories Alone Don't Explain Appetite (58:07)
- How to Manage Food Noise Without a GLP-1 (01:04:46)
- Prehab Before GLP-1s (01:11:09)
- The Fiber, Fat, and Gut Prep Protocol for GLP-1 Users (01:13:56)
- What Clinical Trials Actually Include That Real-World Use Doesn't (01:21:41)
- Do You Need Supplements on a GLP-1? (01:27:15)
- Obesity Is Not a Lifestyle Choice: Shame, Stigma, and GLP-1s (01:29:49)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
LMNT
Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked.
LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for your one-dollar-per-month trial at shopify.com/proof.
Pique
Pique’s Nandaka combines fermented Pu’er tea, full-spectrum Reishi, ceremonial cacao, and L-theanine for calm, sustained energy without the coffee crash. Unlock 20% off and establish your powerful foundation for sustained well-being at Piquelife.com/SIMON.
Pique ships within the U.S. and to Australia, Canada, and select EU countries.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
WHOOP
WHOOP, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
WHOOP ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
The Surgeon Defending Statins, GLP-1s, and Ancel Keys | Dr Terry Simpson
In this episode, I sit down with bariatric surgeon and science communicator Dr Terry Simpson for a wide-ranging conversation about health misinformation, GLP-1 medications, statins, ApoB, the Mediterranean …
Notas do episódio
In this episode, I sit down with bariatric surgeon and science communicator Dr Terry Simpson for a wide-ranging conversation about health misinformation, GLP-1 medications, statins, ApoB, the Mediterranean diet, and the loud contrarians who dominate social media. Terry has familial hypercholesterolemia, a family history of premature cardiovascular disease, and lost 50 pounds on tirzepatide, all of which give him unusual personal stakes in these debates.
What we cover:
- How to think about uncertainty in science, and Terry's heuristic for spotting misinformation
- The Gila monster origin story of GLP-1 medications, and the difference between native and pharmacological GLP-1
- What food noise actually is, and Terry's own experience on tirzepatide
- His personal case for statins, an LDL of 190 brought into the 40s, and an ApoB in the 40s
- A defence of Ancel Keys and the Mediterranean diet
- Where the carnivore, anti-statin, seed oil, and nattokinase narratives fall apart
- Compounded GLP-1s, peptide deregulation, and why the FDA still matters
If you find this episode useful, please leave a rating and review on Apple Podcasts or Spotify and share it with someone who might benefit.
To connect with Dr Terry Simpson, visit terrysimpson.com, find him on TikTok at @drterrysimpson, Instagram at @drterrysimpsonmd, X at @drterrysimpson, and Substack at @drsimpson. His podcast is The Unfiltered MD.
- Intro (00:00)
- Why Carnivore and Anti-Vax Are Today's Biggest Health Lies (01:02)
- Doctors, COVID and the Cost of Speaking Up Online (03:58)
- How to Spot a Health Huckster (13:25)
- Will GLP-1 Drugs Make Bariatric Surgery Obsolete (19:12)
- A Bariatric Surgeon's Personal Decision to Take a GLP-1 Drug (22:54)
- Willpower Is Not the Problem: What Food Noise Actually Feels Like (26:23)
- Why Ancel Keys Was Right and Low Carb Got It Wrong (32:51)
- Mediterranean Diet Results That Stopped a Trial Early (39:50)
- Are GLP-1 Drugs the Greatest Medical Breakthrough This Century (47:38)
- The Real Danger of Buying Compounded GLP-1 Drugs Online (51:27)
- BPC-157 and Peptides: Why FDA Guardrails Actually Matter (59:42)
- Familial Hypercholesterolemia, Statins and a Personal Wake Up Call (01:04:69)
- Inflammation vs. ApoB: What Actually Causes a Heart Attack (01:13:04)
- CT Angiogram Results and Keto CTA Data Explained (01:16:33)
- Fish Oil vs. Eating Fish: Why the Supplement Doesn't Replicate the Food (01:24:35)
- Simon's Plant Based Diet, Seed Oils and Cooking with Olive Oil (01:28:07)
- The Seed Oil Debate: Are People Just Afraid of Modern Chemistry (01:33:17)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. 38TERA ships to the United States, Australia, and New Zealand.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Truemed
Truemed helps qualified customers use pre-tax HSA or FSA dollars on health-related products like fitness, recovery, and sleep tools, often saving around 30% on average. Visit truemed.com/THEPROOF to see what qualifies. This is hands down the best way to make the most of your health dollars.
LMNT
Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked.
LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
WHOOP
WHOOP, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. WHOOP ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
Has Optimisation Culture Gone Too Far? | Sarah Ann Macklin
In this episode, I’m joined by Sarah Ann Macklin to explore the hidden psychological costs of modern wellness culture and why pursuing health can sometimes leave us feeling more anxious, overwhelmed, and …
Notas do episódio
In this episode, I’m joined by Sarah Ann Macklin to explore the hidden psychological costs of modern wellness culture and why pursuing health can sometimes leave us feeling more anxious, overwhelmed, and disconnected.
Sarah shares insights from her new book, Healthy Shouldn’t Be This Hard, as we unpack self-compassion, perfectionism, body image, mindset, and the pressure to constantly optimise every aspect of our lives.
What We Cover
- Why wellness culture can become emotionally exhausting
- The difference between self-esteem and self-compassion
- How mindset shapes long-term health behaviours
- The psychological side of food, body image, and self-worth
- Why optimisation culture can backfire
- Practical ways to build a healthier relationship with yourself
I really enjoyed this conversation with Sarah and appreciated her thoughtful, balanced perspective on what genuine wellbeing actually looks like in practice.
Pre-order Sarah’s new book, Healthy Shouldn’t Be This Hard, and follow her on Instagram, subscribe to her YouTube channel, and read her writing on Substack. You can also learn more about Sarah and her work on her website.
- Intro (00:00)
- What Wellness Culture Is Getting Wrong Right Now (01:16)
- The Chambermaid Study: How Mindset Changes Your Body (05:48)
- The Milkshake Study: Your Perception Affects Your Metabolism (07:06)
- Sarah's Modeling Career, Collapse, and ER Wake-Up Call (09:11)
- How Social Media Weaponizes Self-Comparison (14:01)
- Has Optimization Culture Gone Too Far? (17:58)
- How to Know When Health Habits Become Counterproductive (22:36)
- Self-Compassion Is a Muscle — Here's How to Build It (27:28)
- How Common Is Beating Yourself Up Over Health? (30:26)
- The Chocolate Bar Test: Audit Your Self-Compassion (36:33)
- How to Reconnect with Your Real Hunger Signals (39:36)
- The 3-Step Compassion Framework for Eating Decisions (40:57)
- Discipline vs. Self-Compassion: They're Not Opposites (43:44)
- The "Friend Filter": The Simplest Self-Compassion Tool (57:12)
- What Better Wellness Culture Looks Like in 5 Years (01:02:17)
- Where to Find Sarah's Book "Healthy Shouldn't Be This Hard” (01:04:48)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Pique
Pique’s Nandaka combines fermented Pu’er tea, full-spectrum Reishi, ceremonial cacao, and L-theanine for calm, sustained energy without the coffee crash. Unlock 20% off and establish your powerful foundation for sustained well-being at Piquelife.com/SIMON.
Pique ships within the U.S. and to Australia, Canada, and select EU countries.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
Truemed
Truemed helps qualified customers use pre-tax HSA or FSA dollars on health-related products like fitness, recovery, and sleep tools, often saving around 30% on average. Visit truemed.com/THEPROOF to see what qualifies. This is hands down the best way to make the most of your health dollars.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
What the Headlines Get Wrong About the Future of Meat | Bruce Friedrich
Six years on from our first conversation, global meat consumption is at a record high, and the harms of industrial animal agriculture have only deepened. Bruce Friedrich, founder of the Good Food Institute, is …
Notas do episódio
Six years on from our first conversation, global meat consumption is at a record high, and the harms of industrial animal agriculture have only deepened. Bruce Friedrich, founder of the Good Food Institute, is back on the podcast to argue that the answer is not asking people to eat less, but rebuilding meat itself from the ground up.
Bruce is the author of the new book Meat: How the Next Agricultural Revolution Will Transform Humanity's Favorite Food and Our Future, and one of the most thoughtful voices working on alternative proteins anywhere in the world.
What we cover:
- Why public health messaging on meat has not changed consumption since the 1960s
- The four harms of industrial animal agriculture
- An honest post-mortem on Beyond Meat and the plant-based industry
- Where cultivated meat actually sits in 2026
- Why this transition needs governments, not only venture capital
- The ultra-processed food backlash and what the science really shows
To connect with Bruce Friedrich, you can find his book at meatbook.org, learn more about the Good Food Institute at gfi.org, follow him on X at x.com/BruceGFriedrich, or connect with him on LinkedIn at linkedin.com/in/brucegfriedrich.
Support the work of the Good Food Institute. Listener donations will be matched dollar-for-dollar up to $30,000: gfidonorportal.donorsupport.co
- Intro (00:00)
- Why Feeding Crops to Animals Is Destroying the Planet (02:02)
- Is Everything Getting Worse? A 6-Year Update (07:33)
- Plant-Based Meat: Honest Assessment of What Went Wrong (13:42)
- Did These Products Come to Market Too Early? (19:42)
- What US Government Support for Alt Proteins Should Look Like (25:56)
- 35 Governments Are Now Funding This Research (33:12)
- Why Conservative States Banned Cultured Meat (36:42)
- Are Traditional Meat Companies Actually on Board? (40:07)
- Why Meat Consumption Will Keep Rising Until 2050 (47:06)
- Is Innovation Actually Stalling? The Real Picture (52:10)
- Why Cultivated Meat May Beat Plant-Based to the Finish Line (56:47)
- The Science of Plant Fats vs. Animal Fats Explained (01:00:22)
- The Biggest Blind Spot in Plant-Based Meat Today (01:07:35)
- Cultivated Meat Regulatory Milestones: From Zero to 5 Countries (01:14:13)
- The Only Engineering Challenge That Could Doom Cultured Meat (01:18:05)
- FDA Approval, Chicken with Cancer, and Why Cultured Meat Is Safer (01:20:30)
- Cultured Meat Prices Dropped 100,000x in 12 Years (01:25:21)
- Vow Foods' SpaceX-Inspired Bioreactor Breakthrough (01:30:42)
- How GFI Raises Money And a $30K Donation Match (01:34:55)
- The Protein Myth: Why Impossible Burgers Beat Beef on Nutrition (01:39:31)
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
ProLon
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ProLon ships within the United States.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Cozy Earth
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Cozy Earth ships worldwide.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Improving cholesterol and blood pressure with diet | A Masterclass
Cardiovascular disease is the world's leading killer, and yet the prevention conversation has become noisier and more confused than ever. In this Masterclass I bring together the evidence-first material I think …
Notas do episódio
Cardiovascular disease is the world's leading killer, and yet the prevention conversation has become noisier and more confused than ever. In this Masterclass I bring together the evidence-first material I think is most useful for understanding cholesterol, blood pressure, and long-term heart health.
You will hear from Dr Walter Willett at Harvard, cardiology dietitian Michelle Routhenstein, and nephrologist Dr Raymond Townsend, alongside my own deep dives on plaque regression, the Portfolio Diet, and six landmark trials.
What we cover:
- Legumes as the most underrated longevity food
- The Portfolio Diet and a 30% LDL reduction without statins
- What six trials tell us about diet, plaque progression, and regression
- Dr Walter Willett on saturated fat, seed oils, and dairy
- Sodium, potassium, and the DASH diet for blood pressure
- Why diet, exercise, and medications work best together
The earlier you start, the more leverage you have. This Masterclass is meant to give you a clearer map of what actually works.
If this episode was useful, please consider leaving a rating or review on Apple or Spotify. It helps more than you might think.
- Most Underrated Foods for Long-Term Health (00:00)
- Can You Actually Reverse Artery Plaque? (03:07)
- How to Lower ApoB Without Statins (07:19)
- The Portfolio Diet: Cut LDL by 30% (09:11)
- 6 Trials That Changed Heart Disease Science (16:30)
- Michelle Routhenstein: Why Doctors Skip ApoB Testing (20:07)
- Best Food Swaps to Lower ApoB (27:04)
- RFK Jr, Seed Oils, and the Saturated Fat Debate (35:48)
- Full-Fat vs. Low-Fat Dairy and Your Heart (38:27)
- Blood Pressure: Why the Sodium-Potassium Ratio Matters (43:08)
- Walter Willett: The True Mediterranean Diet (45:19)
- Are Seed Oils Inflammatory? The Science (50:50)
- Should You Cook with Olive Oil or Not (57:44)
- Full-Fat vs. Low-Fat Dairy: 2025 Research (01:03:00)
- Dairy vs. Soy Milk: Health and Planet (01:09:32)
- Plant Protein vs. Animal Protein: The Data (01:14:52)
- Raymond Townsend: Top Levers for Lowering Blood Pressure (01:16:38)
- Best Exercise Type for Blood Pressure (01:20:13)
- How Sodium Raises Blood Pressure Over Time (01:24:48)
- Potassium vs. Sodium: Why the Ratio Is Everything (01:30:40)
- Should You Watch Salt with Normal Blood Pressure (01:43:51)
- Why the DASH Diet Works as Well as a Drug (01:48:31)
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. 38Tera ships to the United States, Australia, and New Zealand.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
SwimClub
SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get 25% off your first order with code THEPROOF.
HomeServe
Help protect your home systems – and your wallet – with HomeServe against covered repairs. Plans start at just $4.99 a month. Go to HomeServe.com to find the plan that’s right for you.
HomeServe is not available everywhere. Most plans range between $4.99 to $11.99 a month your first year. Terms apply on covered repairs.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.
The Peptides Quietly Accelerating Aging | Dr Valter Longo
The peptide and GLP-1 conversation has reached a fever pitch. Growth-hormone-releasing peptides are being marketed as longevity tools, GLP-1s are being treated as a default rather than a last resort, and a …
Notas do episódio
The peptide and GLP-1 conversation has reached a fever pitch. Growth-hormone-releasing peptides are being marketed as longevity tools, GLP-1s are being treated as a default rather than a last resort, and a wellness aesthetic of higher IGF-1, more muscle, and less fat is being sold as the route to a longer life. In this episode, I sit down with Dr Valter Longo, Professor of Gerontology at USC and Director of the USC Longevity Institute, to look at what the data actually says.
Valter developed the Fasting-Mimicking Diet, has led foundational work on the growth hormone, IGF-1, insulin, and TOR axis across yeast, mice, and humans, and runs non-profit longevity foundation clinics in Europe and the US. He calls himself the anti-biohacker and makes the case using the totality of evidence rather than the loudest claim.
What we cover:
- The peptide boom and why every line of evidence cuts the other way
- The body composition reality of GLP-1s after 3 to 4 years
- The optimal IGF-1 range and how to land there with food and timing
- The Fasting-Mimicking Diet across more than 47 clinical trials, including the biological-age reduction studies
- The Harvard plant-versus-animal protein data, properly read
- A grounded case against ketogenic patterns for longevity and what to eat instead
If this conversation lands, a quick rating or review on Apple Podcasts or Spotify makes a real difference.
To follow more of Dr Valter Longo's work, visit his website, find him on Instagram, and explore the work of the Create Cures Foundation, the Valter Longo Foundation, the Longevity Technology Institute, and the European Longevity Institute through his published research and his book The Longevity Diet.
- Intro (00:00)
- The Peptide Boom and What Is Actually Being Sold (00:01)
- GLP-1s: 92 Per Cent Drop-Out and the Body Composition Math (00:02)
- The Fasting-Mimicking Diet Reverses Western-Diet Damage (00:13)
- Snell, Ames, and Laron Dwarf Mice (00:18)
- The Laron Syndrome Cohort in Ecuador (00:24)
- Acromegaly and the Cost of High Growth Hormone (00:28)
- The Optimal IGF-1 Range: 120 to 160 ng/mL (00:50)
- Plant vs Animal Protein, Properly Read (00:57)
- The Anti-Keto Case from Okinawa to Loma Linda (01:08)
- Stanford Crohn's, Miami UC, and Rome Kidney Disease (01:22)
- Biological Age Reduction After Three FMD Cycles (01:25)
- FMD Safety Across More Than a Million Users (01:31)
- The Longevity Diet: Eat More, Eat Better (01:43)
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
Pique
Pique’s Nandaka combines fermented Pu’er tea, full-spectrum Reishi, ceremonial cacao, and L-theanine for calm, sustained energy without the coffee crash. Unlock 20% off and establish your powerful foundation for sustained well-being at Piquelife.com/SIMON.
Pique ships within the U.S. and to Australia, Canada, and select EU countries.
Function Health
Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States.
Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico.
Truemed
Truemed helps qualified customers use pre-tax HSA or FSA dollars on health-related products like fitness, recovery, and sleep tools, often saving around 30% on average. Visit truemed.com/THEPROOF to see what qualifies. This is hands down the best way to make the most of your health dollars.
IM8
With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com.
IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America.
WHOOP
WHOOP, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
WHOOP ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @theproof
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
The Diet That Lowers Cholesterol Like a Statin | Dr Andrea Glenn
Plant-based nutrition has rarely been more contested. Seed oils are vilified, butter is celebrated, protein is treated as a pure quantity question, and nutrition epidemiology is routinely dismissed by people …
Notas do episódio
Plant-based nutrition has rarely been more contested. Seed oils are vilified, butter is celebrated, protein is treated as a pure quantity question, and nutrition epidemiology is routinely dismissed by people who have never read one of its papers. In this episode, I sit down with Dr Andrea Glenn, an Assistant Professor at NYU and Visiting Scientist at the Harvard T.H. Chan School of Public Health, to look at what the strongest evidence actually shows.
We cover the recent plant-versus-animal protein data from the Nurses' Health Studies and Health Professionals Follow-up Study, the Portfolio Diet, the new CHEAP trial, the JAMA Internal Medicine butter and plant oil paper, and the new 2026 AHA dietary guidance.
What we cover:
- The plant-to-animal protein ratio and its association with cardiovascular and coronary heart disease risk
- The Portfolio Diet, what it contains, and how its LDL-lowering effects compare to a low-dose statin
- Butter, beef tallow, tropical oils, and what the latest mortality data show
- Why "low-carb" is not one diet, and why food sources matter as much as the macronutrient breakdown
- A grounded defence of nutrition epidemiology and the role of food frequency questionnaires
- Practical takeaways for how to eat in line with the new AHA guidance
This is the conversation I wanted to have for anyone tired of nutrition by hashtag. If it lands, a quick rating or review on Apple Podcasts or Spotify makes a real difference.
To follow more of Dr Andrea Glenn's work, find her on Instagram at instagram.com/andrea.glenn.rd, on X at x.com/andreaglennrd, and on LinkedIn at linkedin.com/in/andrea-glennrd.
- Intro (00:00)
- Plant vs Animal Protein Ratio and Heart Disease (01:17)
- Does Total Protein Amount Also Affect CVD Risk? (05:33)
- Why Nutrition Epidemiology Critics Often Get It Wrong (11:00)
- Where Epidemiology Fits in the Evidence Hierarchy (17:28)
- Sensitivity Analyses: How Scientists Test Their Results (22:16)
- What It's Like Doing Science at Harvard (28:55)
- The Portfolio Diet: Origins and the Science Behind It (32:21)
- The CHEAP Trial: Testing Portfolio Diet Long-Term (41:03)
- Portfolio Diet in Cohort Studies: What the Data Shows (50:24)
- Unsaturated Fats: Are They Inherently Heart-Protective? (56:16)
- Phytosterol Supplements: LDL Benefits vs Safety Questions (01:00:06)
- Butter vs Plant Oils: What Mortality Data Actually Shows (01:06:57)
- Plant vs Animal MUFAs and Type 2 Diabetes Risk (01:12:11)
- Low-Carb Diet Quality and Diabetes Risk: New Data (01:15:37)
- 2026 AHA Dietary Guidelines: Key Differences Explained (01:20:23)
- Portfolio Diet's Potential to Reduce Disease Burden (01:26:35)
This episode is brought to you by:
38TERA
Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
38Tera ships to the United States, Australia, and New Zealand.
LMNT
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LMNT ships to the U.S. and Canada, with sparkling flavors available only in the contiguous U.S.
Shopify
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Momentous
My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com.
Momentous ships to many countries worldwide depending on local import regulations.
Eight Sleep
Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.
Eight Sleep ships to the U.S. (excluding Alaska, Hawaii, and territories), Canada, Mexico, most of the EU, the U.K., Australia, the UAE, Saudi Arabia, and Switzerland.
Simon Hill, MSc, BSc (Hons)
- Creator of theproof.com
- Host of The Proof with Simon Hill
- Author of The Proof is in the Plants
Subscribe & Connect:
- YouTube
- Apple Podcasts
- Spotify
- Instagram: @simonhill
- Twitter: @theproof
- Facebook: The Proof with Simon Hill
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