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This Week in Microbiology

This Week in Microbiology

Novo367: Milestones at Michigan State7 de novembro de 2026 · 1 h 3 min
Episódios
368
Publicação
quinzenal
Último episódio
7 nov 2026

Sobre o podcast

This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

Episódios 368

  1. 367: Milestones at Michigan State

    1 h 3 minEpisódio 367

    TWiM travels to Michigan State University to celebrate their designation as an ASM Milestones in Microbiology site, and speaks with Vic DiRita, Elizabeth Heath-Heckman, Rich Lenski, and Jim Tiedje about their …

    Notas do episódio

    TWiM travels to Michigan State University to celebrate their designation as an ASM Milestones in Microbiology site, and speaks with Vic DiRita, Elizabeth Heath-Heckman, Rich Lenski, and Jim Tiedje about their careers and their research.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  2. 366: Our Vanishing Ancient Gut Microbes

    1 h 7 minEpisódio 366

    TWiM explains a bacterial antiviral defense system that uses a noncoding RNA template to build tandem-repeat DNA through a mechanism that parallels how eukaryotic telomerase extends telomeres, and genome …

    Notas do episódio

    TWiM explains a bacterial antiviral defense system that uses a noncoding RNA template to build tandem-repeat DNA through a mechanism that parallels how eukaryotic telomerase extends telomeres, and genome sequencing of the Tsimane of Bolivia and the Hadza of Tanzania which reveals over a thousand gut bacterial species shared between the two populations, many now vanishing from industrialized humans, suggesting they co-migrated with our ancestors out of Africa and into the Americas.

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    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  3. 365: Bacteria Inside a Fungus Sabotage Plant Defenses

    51 minEpisódio 365

    TWiM explains how bacterial endosymbionts enhance fungal virulence by disrupting the protective rhizobiome, and the development of rationally engineered Salmonella typhimurium strains with enhanced safety and …

    Notas do episódio

    TWiM explains how bacterial endosymbionts enhance fungal virulence by disrupting the protective rhizobiome, and the development of rationally engineered Salmonella typhimurium strains with enhanced safety and antitumor efficacy.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  4. 364: DNA Damage as Defense Against Bee Pathogens

    47 minEpisódio 364

    TWiM wonders why archaea are not pathogenic, and reveals how a colibactin produced by a honeybee gut symbiont defends against pathogens. Become a patron of TWiM. Links for this episode: Why are archaea not …

    Notas do episódio

    TWiM wonders why archaea are not pathogenic, and reveals how a colibactin produced by a honeybee gut symbiont defends against pathogens.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  5. 363: Why Vegetables Are Good for Your Heart

    58 minEpisódio 363

    TWiM explains the finding that Bunsen burners do not decrease deposition of microbe-containing particles, and how gut microbiota generate dinitrosyl iron complexes with cardiometabolic benefits. Hosts: Vincent …

    Notas do episódio

    TWiM explains the finding that Bunsen burners do not decrease deposition of microbe-containing particles, and how gut microbiota generate dinitrosyl iron complexes with cardiometabolic benefits.

    Hosts: Vincent Racaniello and Michael Schmidt

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  6. 362: When Gut Bacteria Share Chromosomes

    52 minEpisódio 362

    TWiM explains how movement of DNA among gut bacteria drive large-scale genome mosaicism, and validation of a method for detection of Cyclospora cayetanensis in outbreak-linked fresh produce. Hosts: Vincent …

    Notas do episódio

    TWiM explains how movement of DNA among gut bacteria drive large-scale genome mosaicism, and validation of a method for detection of Cyclospora cayetanensis in outbreak-linked fresh produce.

    Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  7. 361: Bacteria and Colon Cancer Recurrence

    53 minEpisódio 361

    TWiM explains the discovery of an avirulent bacterial signature associated with the development of recurrence following colorectal cancer surgery, and phage-derived proteins and conjugates that induce pilus …

    Notas do episódio

    TWiM explains the discovery of an avirulent bacterial signature associated with the development of recurrence following colorectal cancer surgery, and phage-derived proteins and conjugates that induce pilus detachment.

    Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

    Take the TWiM Survey

  8. 360: Nitrogen Fixation Goes Eukaryotic

    56 minEpisódio 360

    TWiM explains major implications of the link between plastic pollution and antimicrobial resistance, and the discovery of a new organelle, the nitrogen-fixing nitroplast. Hosts: Vincent Racaniello, Michael …

    Notas do episódio

    TWiM explains major implications of the link between plastic pollution and antimicrobial resistance, and the discovery of a new organelle, the nitrogen-fixing nitroplast.

    Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  9. 359: Kin Killing and Metal Hunger

    48 minEpisódio 359

    TWiM explains how cannibalism shapes biofilm structure and composition in Bacillus subtilis, and the importance of manganese uptake in uropathogenic E. coli during urinary tract infection. Become a patron of …

    Notas do episódio

    TWiM explains how cannibalism shapes biofilm structure and composition in Bacillus subtilis, and the importance of manganese uptake in uropathogenic E. coli during urinary tract infection.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  10. 358: Gut Microbes and ALS

    58 minEpisódio 358

    TWiM explains the connection between inflammation caused by microbial glycogen in the gut and amyotrophic lateral sclerosis, and how disruption of cysteine metabolism leads to synthetic lethality and in vivo …

    Notas do episódio

    TWiM explains the connection between inflammation caused by microbial glycogen in the gut and amyotrophic lateral sclerosis, and how disruption of cysteine metabolism leads to synthetic lethality and in vivo fitness impairment in Acinetobacter baumannii.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  11. 357: Remembering Elio at Tufts

    56 minEpisódio 357

    TWiM visits Tufts University School of Medcine and are joined by John Coffin, Michael Malamy, and Verna Manni for a tribute to Elio Schaechter who was chair of Molecular Biology and Microbiology for 23 years …

    Notas do episódio

    TWiM visits Tufts University School of Medcine and are joined by John Coffin, Michael Malamy, and Verna Manni for a tribute to Elio Schaechter who was chair of Molecular Biology and Microbiology for 23 years.

    Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

    Guests: John Coffin, Michael Malamy, and Verna Manni

    Subscribe to TWiM (free) on Apple Podcasts, Stitcher, RSS, or by email.

    Become a Patron of TWiM!

    Music used on TWiM is by Ronald Jenkees.

    Send your microbiology questions and comments to [email protected]

  12. TWiM 356: Nanopore to the bone

    49 minEpisódio 356

    TWiM explains how Streptococcus mitis bacteriocins drive contact-dependent lysis of S. pneumoniae facilitating transformation, and microbial dominance in diabetic foot osteomyelitis determined with nanopore …

    Notas do episódio

    TWiM explains how Streptococcus mitis bacteriocins drive contact-dependent lysis of S. pneumoniae facilitating transformation, and microbial dominance in diabetic foot osteomyelitis determined with nanopore sequencing.

    Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

    Subscribe to TWiM (free) on Apple Podcasts, Stitcher, RSS, or by email.

    Links for this episode

    Become a Patron of TWiM!

    Music used on TWiM is by Ronald Jenkees.

    Send your microbiology questions and comments to [email protected]

  13. 355: Bacteria Complete Your tRNA

    56 minEpisódio 355

    TWiM explains how an enhanced domestication method allows for growth of uncultured bacteria, and identification of the oncogene SLC35F2 as is a high-specificity transporter for the micronutrients queuine and …

    Notas do episódio

    TWiM explains how an enhanced domestication method allows for growth of uncultured bacteria, and identification of the oncogene SLC35F2 as is a high-specificity transporter for the micronutrients queuine and queuosine.

    Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Guest: Mark O. Martin

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  14. 354: How a Gut Microbe Worsens Heart Disease

    59 minEpisódio 354

    TWiM explains a candidate signature of health in the gut microbial community, and how an intestinal bacterium exacerbates cardiac ischemia/reperfusion injury. Hosts: Vincent Racaniello, Michael Schmidt, Michele …

    Notas do episódio

    TWiM explains a candidate signature of health in the gut microbial community, and how an intestinal bacterium exacerbates cardiac ischemia/reperfusion injury.

    Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Petra Levin.

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  15. 353: Microbial Metabolism of Food Allergens

    47 minEpisódio 353

    TWiM explains how to use microbes to enhance maize yield and reduce corn rootworm damage, and how the human microbiota modulates IgE-mediated reactions to foods through allergen metabolism. Hosts: Michael …

    Notas do episódio

    TWiM explains how to use microbes to enhance maize yield and reduce corn rootworm damage, and how the human microbiota modulates IgE-mediated reactions to foods through allergen metabolism.

    Hosts: Michael Schmidt, Petra Levin, and Michele Swanson.

    Guest: Mark O. Martin

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  16. 352: Microbial Gut Biosensors

    60 minEpisódio 352

    TWiM reveals the archaeal roots of eukaryotic life, and a building a gut malabsorption biosensor with bacteria. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used …

    Notas do episódio

    TWiM reveals the archaeal roots of eukaryotic life, and a building a gut malabsorption biosensor with bacteria.

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  17. 351: Resistance Reboot

    59 minEpisódio 351

    TWiM discusses the use of bacteriophage-loaded microneedle patches for targeted and minimally disruptive foodborne pathogen decontamination, and a conjugal gene drive-like system that efficiently suppresses …

    Notas do episódio

    TWiM discusses the use of bacteriophage-loaded microneedle patches for targeted and minimally disruptive foodborne pathogen decontamination, and a conjugal gene drive-like system that efficiently suppresses antibiotic resistance in bacteria.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  18. 350: TWiM Goes to College

    53 minEpisódio 350

    Nancy and Maggie join TWiM to share how and why they created a freely available ebook of TWiM-based science literacy resources and classroom exercises that support teaching across key microbiology and molecular …

    Notas do episódio

    Nancy and Maggie join TWiM to share how and why they created a freely available ebook of TWiM-based science literacy resources and classroom exercises that support teaching across key microbiology and molecular biology topics.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  19. 349: Punctured to Death by Spikes

    59 minEpisódio 349

    TWiM explains how mechano-bactericidal surfaces made from diverse materials and patterned with spikes kill bacteria on contact, and virus-host evolution is reshaped by microgravity aboard the International …

    Notas do episódio

    TWiM explains how mechano-bactericidal surfaces made from diverse materials and patterned with spikes kill bacteria on contact, and virus-host evolution is reshaped by microgravity aboard the International Space Station.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  20. 348: The Bark Side of the Microbiome

    54 minEpisódio 348

    TWiM explains the finding that owning a dog during adolescence alters the microbiota and improves mental health, and the molecular basis for multidrug efflux by an anaerobic-associated …

    Notas do episódio

    TWiM explains the finding that owning a dog during adolescence alters the microbiota and improves mental health, and the molecular basis for multidrug efflux by an anaerobic-associated resistance-nodulation-cell division transporter.

    Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Petra Levin.

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  21. 347: At Wound's Edge

    55 minEpisódio 347

    TWiM explains how S. aureus pathogenicity is a dynamic, niche-specific choreography that constantly recalibrates in response to the host microenvironment, and short chain fatty acids produced by commensal …

    Notas do episódio

    TWiM explains how S. aureus pathogenicity is a dynamic, niche-specific choreography that constantly recalibrates in response to the host microenvironment, and short chain fatty acids produced by commensal microbiota reduces its competitive fitness.

    Hosts: Michael Schmidt, Michele Swanson and Petra Levin.

    Guest: Mark O. Martin

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  22. 346: Metabolism and Porin Permeability

    54 minEpisódio 346

    TWiM explains how competition for nutrients anticipates and potentially mitigate drug side effects on the gut microbiota, and metabolic control of porin permeability influences antibiotic resistance. Hosts …

    Notas do episódio

    TWiM explains how competition for nutrients anticipates and potentially mitigate drug side effects on the gut microbiota, and metabolic control of porin permeability influences antibiotic resistance.

    Hosts: Vincent Racaniello, Michael Schmidt and Petra Levin

    Guest: Mark O. Martin

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  23. 345: Faster Than Rocks!

    54 minEpisódio 345

    TWiM explains a biological mechanism that links sulfur and iron cycling in anoxic environments, and "swashing," a form of surface movement in which bacteria migrate without active propulsion. Hosts: Michael …

    Notas do episódio

    TWiM explains a biological mechanism that links sulfur and iron cycling in anoxic environments, and "swashing," a form of surface movement in which bacteria migrate without active propulsion.

    Hosts: Michael Schmidt, Michele Swanson, and Petra Levin

    Guest: Mark O. Martin

    Subscribe to TWiM (free) on Apple Podcasts, RSS, or by email.

    Links for this episode

    Become a Patron of TWiM!

    Music used on TWiM is by Ronald Jenkees.

    Send your microbiology questions and comments to [email protected]

  24. 344: Ant Yogurt and Fine Chocolate

    1 h 6 minEpisódio 344

    TWiM reveals the bacteria, acids, and enzymes behind yogurt made with ants, and a defined set of microbes that reproduces attributes of fine flavor chocolate fermentation Hosts: Vincent Racaniello, Michael …

    Notas do episódio

    TWiM reveals the bacteria, acids, and enzymes behind yogurt made with ants, and a defined set of microbes that reproduces attributes of fine flavor chocolate fermentation

    Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

    Guest: Mark O. Martin

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  25. 343: Nucleotides to the Defense

    44 minEpisódio 343

    TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides. Hosts: Michael Schmidt and Mark O. Martin Become a patron of TWiM. Links for this episode: Decoy …

    Notas do episódio

    TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides.

    Hosts: Michael Schmidt and Mark O. Martin

    Become a patron of TWiM.

    Links for this episode:

    • Decoy cyclic nucleotides in phage defense (Nature)

    • CRISPR defense with nucleotides (Nature)

    • A decoy defence molecule to set a trap for viruses (Nature)

    • Cyclic oligonucleotide-based antiphage signaling system immunity (Curr Opin Immunol)

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  26. 342: The Microbiome, Pancreatic Cancer, and Sleep Quality

    54 minEpisódio 342

    TWiM explains studies that show that the oral bacterial and fungal microbiome are risk factors for pancreatic cancer, and the gut microbiome and pyruvate metabolism of older adults are a link between sleep …

    Notas do episódio

    TWiM explains studies that show that the oral bacterial and fungal microbiome are risk factors for pancreatic cancer, and the gut microbiome and pyruvate metabolism of older adults are a link between sleep quality and frailty.

    Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson.

    Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email.

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  27. 341: Sea Star Wasting Disease

    49 minEpisódio 341

    TWiM reveals a Vibrio as the causative agent of sea star wasting disease, and using microcolony-seq to uncover phenotypic inheritance from single cells. Hosts: Michael Schmidt and Michele Swanson Guest: Mark O …

    Notas do episódio

    TWiM reveals a Vibrio as the causative agent of sea star wasting disease, and using microcolony-seq to uncover phenotypic inheritance from single cells.

    Hosts: Michael Schmidt and Michele Swanson

    Guest: Mark O. Martin

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  28. 340: Microbes in Trees and Plants

    49 minEpisódio 340

    TWiM explores the varied and distinct microbiome of trees, and an array of biopesticidal metabolites against mosquito larvae isolated from a Mediterranean island. Become a patron of TWiM. Links for this …

    Notas do episódio

    TWiM explores the varied and distinct microbiome of trees, and an array of biopesticidal metabolites against mosquito larvae isolated from a Mediterranean island.

    Become a patron of TWiM.

    Links for this episode:

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to [email protected]

  29. 339: Missing the Company of Elio

    59 minEpisódio 339

    TWiM pays tribute to Elio Schaechter, former TWiM host, blogger, and microbiologist extraordinaire, then reviews the finding that Archaea produce peptidoglycan hydrolases that kill bacteria - a form of …

    Notas do episódio

    TWiM pays tribute to Elio Schaechter, former TWiM host, blogger, and microbiologist extraordinaire, then reviews the finding that Archaea produce peptidoglycan hydrolases that kill bacteria - a form of competition.

    Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Petra Levin.

    Guest Mark O. Martin.

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Links for this episode

    Send your microbiology questions and comments (email or recorded audio) to [email protected]

  30. 338: Rewriting the Code of Life

    53 minEpisódio 338

    TWiM discusses outbreak of Legionnaires disease in Harlem NY, an automated whole genome sequencing platform for bacterial strain typing in clinical microbiology laboratories, building E. coli with a 57-codon …

    Notas do episódio

    TWiM discusses outbreak of Legionnaires disease in Harlem NY, an automated whole genome sequencing platform for bacterial strain typing in clinical microbiology laboratories, building E. coli with a 57-codon genetic code.

    Links for this episode

    Become a patron of TWiM.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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