TWiV 1360: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello frustration continues over the increasing number of measles infections, Kennedy's undermining of vaccines, perpetuation of autism- vaccine, autism-tylenol myths, an outbreak of hepatitis A virus in the US, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine recommendations, Legionnaires disease and screw worm cases, and before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, economics of a measles outbreak in Chicago, what defines reactogenicity of the mRNA COVID vaccines, the on-going delay by HHS of COVID shots for children, neuropsychiatric symptoms of long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

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Links for this episode

• CDC adds 177 cases to US measles total but has yet to confirm deaths in Pennsylvania (CIDRAP)
• Kennedy questions vaccine safety at Children's Health Defense event (CIDRAP)
• Trump says some routine immunizations will be split into five separate shots. Vaccine experts say it won't work (CNN)
• Multistate Hepatitis A Outbreak Potentially Linked to Frozen Clams (CDC: Hepatitis A)
• Cumulative Incidence and Prevalence of Autism Spectrum Disorder (JAMA Pediatrics)
• Data and Statistics on Autism Spectrum Disorder (CDC: Autism Spectrum Disorder)
• Study uncovers no evidence of autism epidemic, despite claims (CIDRAP)
• Florida confirms a death from dengue as the state struggles with one of its worst recent outbreaks (AP News)
• Legionnaires' Disease (NYC: Health)
• Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service)
• CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom)
• Democratic Republic of Congo (AP News)
• Ebola virus (AP News)
• Congo begins Ebola vaccinations for health workers in the epicenter of the outbreak (AP News)
• Ebola dashboard (ebola.fyi)
• EBOLA: The Democratic Republic of the Congo, 2026 (WHO)
• Bundibugyo virus disease outbreak Democratic Republic of the Congo(WHO: Democratic Republic of Congo)
• Ebola Outbreak: Current Situation (CDC:Ebola)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Measles (VDH: Virginia Department of Health)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• HAP's Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania)
• Measles (Commonwealth of Pennsylvania)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Pennsylvania asks CDC for emergency assistance amid RFK Jr. clash over measles(The Hill)
• Pennsylvania measles-associated deaths climb to four as outbreak grows (Reuters)
• Pennsylvania asks for CDC measles help amid Kennedy dispute (Reuters)
• Republican senator faults Trump vaccine policy for US measles deaths as panel weighs health nominees (Reuters)
• US CDC works on standard definition for measles deaths as cases rise (Reuters)
• Cost of a Measles Outbreak in an Urban Shelter (JAMA Open Network)
• Measles outbreak in Chicago shelter cost nearly $9 million, CDC estimates (CIDRAP)
• World's most contagious virus hits major US airport as officials warn of possible exposure (FoxNews)
• Measles Cases and Outbreaks (CDC: Rubeola)
• Laboratory Testing for Measles (CDC: Measles (Rubeola)
• Measles Clinical Diagnosis Fact Sheet (CDC: Measles (Rubeola)
• Measles Serology Testing (CDC: Measles (Rubeola)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots(CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• Immunogenicity and safety of an MF59-adjuvanted cell-derived higher-dose quadrivalent influenza vaccine (aQIVc) in adults aged 50 years or older: a phase 3 randomised controlled trial (LANCET: Infectious Diseases)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• RSV Immunization Effectiveness and Safety for the 2026-2027 Respiratory Season (JAMA)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Moderna Receives U.S. FDA Approval for Updated 2026-2027 COVID-19 Vaccines (Moderna)
• Novavax's Partnership Strategy Continues to Deliver with XFG-adapted Nuvaxovid™ Approvals in the U.S., EU and Japan for 2026-2027 Vaccination Season (novavax)
• Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine (Pfizer)
• FDA approves new COVID vaccines (CIDRAP)
• Baseline interferon signaling in monocytes and antibody-mediated innate activation are associated with reactogenicity to mRNA vaccines (Science Translational Medicine)
• Coronavirus Disease 2019 (COVID-19) Hospitalization Surveillance Network (COVID-NET)(CDC: Covid)
• CDC inaction delays COVID shots for low-income children (CIDRAP)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Loss of vesicular monoamine transporter 2 in striatum of long COVID and relationship to neuropsychiatric symptoms (eBioMedicine)
• Reaching out to US house representative
• <a href="https://www.microb