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症状消失≠病好了,自身免疫疾病如何摆脱反反复复|O课超话E.256

November 6, 2026 · 1 h 16 min

Show notes

很多红斑狼疮、狼疮肾炎、类风湿关节炎、特发性膜性肾病的病友,都会有一段很无力的经历:经过治疗,关节不痛了、脸上的红斑消退,化验单看上去也好转,感觉自己已经好了。可没过多久,劳累、感冒之后病情又再次卷土重来。激素吃了减、减了又要加上,始终没办法彻底停药。
这也是《O课超话》系列播客前几期评论区被反复问到的问题:为什么自免病这么容易复发?明明没有不舒服,为什么医生还是不让我停药?到底什么样才算真正的病情好转?我们追求的“根治”,放在自身免疫疾病里,现实的边界又在哪里。当前医生手上的治疗疾病的武器越来越多,我们的治疗目标也在发生改变——过去是压制症状,现在追求“深度缓解”,甚至实现免疫的重置重启。
这一期,我们来聊聊到底什么是深度缓解?为什么表面症状消失不等于体内的炎症已经熄灭?想要降低复发,B细胞的清除要做到什么程度?深度缓解又能给患者的肾脏、关节这些重要器官带来怎样长远的保护。
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