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失眠、焦虑、抑郁:同一张神经网如何影响我的情绪与睡眠?对谈睡眠疼痛罗博士-Vol102

July 14, 2026 · 1 h 6 min

Show notes

抑郁不是"想不开",是大脑的器质性疾病——神经递质、神经网络出了问题。我们这期请回返场嘉宾、佑安医院麻醉科罗超医生,从神经生物学最新研究重新理解抑郁症。
围绕 2018 年浙大胡海岚团队 Nature 论文(外侧缰核簇状放电)与 2025/2026 年腺苷通路新研究,罗医生串起一张关系网:线粒体代谢→腺苷→外侧缰核/中缝核→多巴胺/焦虑;肠道菌群→血清素→褪黑素→睡眠;HPA 轴→皮质醇→交感/副交感。睡眠是打破"抑郁↔失眠"恶性循环的关键节点——"睡眠是所有健康基石的基石"。
最后聊到麻醉睡眠治疗的差异化思路:认知行为治疗是一线,神经调控(星状神经节阻滞、经颅磁、迷走神经刺激)不依赖药物,右美托咪定诱导自然睡眠,艾司氯胺酮快速抗抑郁。主播Nixon分享了自己做星状神经节阻滞的真实体验。
02:08 查不出病的心慌胸闷胃胀:是交感神经在报警
严重的焦虑状态会激发躯体症状——心慌、胸闷、潮热...去小宇宙查看完整单集简介
在小宇宙查看该单集文稿

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