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E152 - Neurophysiologist: How to Train Your Brain to Be Disgustingly Sharp

November 9, 2026 · 1 h 37 min

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» Produced by Hack You Media: pioneering a new category of content at the intersection of health performance, entrepreneurship & cognitive optimisation.

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Louisa Nicola is a neurophysiologist who breaks down why zone two training creates the most profound brain changes, why resistance training (especially legs) builds a bigger brain on an MRI, and why most people are wasting time with peptides instead of fixing sleep and nutrition first.


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00:00 Introduction

02:00 The science of exercise and brain health

07:03 Measuring fitness and understanding VO2 max

18:08 Resistance training as a longevity tool

24:05 Optimising workouts with mind-muscle connection

31:42 The role of music in athletic performance

38:53 Debunking creatine myths and benefits

49:32 Navigating the risks of unapproved peptides

57:57 The impact of GLP-1s and weight loss drugs

1:02:18 Genetic risks and testing for Alzheimer's disease

1:07:02 Managing sleep disruption and racing thoughts

1:17:49 Training sustained attention and focus

1:23:14 Separating myth from reality on multitasking

1:26:53 Upbringing, resilience, and high performance

1:32:56 Belief, science, and the human body


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» Follow Louisa

Instagram: https://www.instagram.com/louisanicola_/?hl=en

The Brain Code: https://go.neuroathletics.com.au/brain-code

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