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Sleep and PsA: Exploring the Hidden Connection

November 7, 2025 · 20 min

Show notes

In this episode of Inside GRAPPA, host Dr. Mio Nakamura (University of Michigan) speaks with Dr. Tina Bhutani-Jacques, MD, MAS, FAAD (Synergy Dermatology / University of California San Francisco) about her groundbreaking study on the role of sleep in psoriasis disease severity. Funded by the GRAPPA Pilot Research Grant, Dr. Bhutani-Jacques’s work is the first prospective cohort study to objectively examine sleep patterns in psoriasis patients.


💡 Together, they explore:

  • How a patient’s unexpected experience sparked the idea to investigate sleep and psoriasis
  • The design and findings of the pilot study using three nights of polysomnography in patients and healthy controls
  • Early results showing reduced sleep efficiency, more awakenings, and nearly an hour less sleep per night among psoriasis patients
  • The potential link between poor sleep, inflammation, and cardiovascular comorbidities
  • Practical advice for clinicians on discussing sleep with psoriasis patients
  • Next steps, including home-based sleep studies using wearables for more naturalistic data


🎧 Tune in for an engaging discussion that highlights how sleep—often overlooked—may be a key factor in understanding psoriatic disease and improving patient outcomes.

🔗 Learn more about GRAPPA’s research initiatives at grappanetwork.org.

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