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Exploring Sex Differences in Psoriatic Arthritis: Biomarkers and Beyond

May 1, 2025 · 22 min

Show notes

How do biological sex differences shape the clinical presentation and treatment outcomes in psoriatic arthritis (PsA)? In this episode of Inside GRAPPA, Dr. Hanna Johnsson delves into groundbreaking research led by Steven Dang and Dr. Lihi Eder, supported by the GRAPPA Pilot Research Grant. Their study explores sex-related differences in PsA through proteomic analysis, uncovering unique biomarkers and pathways that could redefine personalized medicine for PsA patients.


What You'll Learn:
  • The rationale behind investigating sex-specific differences in PsA.  
  • Insights into how immune and inflammatory profiles differ between males and females.  
  • Key findings from proteomic studies, including pivotal proteins and pathways like NETosis, Rho GTPase, and cytokine signaling.  
  • The potential for sex-specific biomarkers to guide diagnosis and treatment in PsA.


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