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Bayesian Principal Stratification: Modeling Treatment Effects

September 11, 2026 · 5 min

Show notes

Today's clip is from Episode 164, featuring Andrew Gelman, Aki Vehtari & Richard McElreath. In this conversation, Andrew explains how Bayesian principal stratification can be used to reason about treatment effects when there is an intermediate treatment or outcome that is only partially observed.

He discusses how latent variables can represent whether someone would take a stage-two treatment, and how pre-treatment characteristics such as age, location, and past spending can help build a model for this process.

Richard connects the problem to the broader distinction between per-protocol and intent-to-treat analyses, and they discuss how standard approaches such as instrumental variables can be understood as special cases of more general Bayesian models. It's a useful example of how Bayesian modeling can represent the full process behind a causal question rather than relying on simplifying assumptions.

Full discussion here

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