Skip to content

244: Group A Strep: Breaking Down the New IDSA Guidelines

September 18, 2026 · 57 min

Show notes

Group A Streptococcus (GAS) is a common cause of pharyngitis, but deciding who should be tested and which testing method to use isn't always straightforward. In 2025, the Infectious Diseases Society of America (IDSA) released updated guidelines on Group A streptococcal pharyngitis, bringing renewed attention to diagnostic stewardship and the use of clinical scoring systems to help guide testing decisions.

In this episode of Let's Talk Micro, Dr. Christopher Doern returns to the podcast to break down the updated IDSA guidelines and what they may mean for clinical practice. We discuss clinical scoring systems such as Centor and McIsaac, antigen testing, culture, molecular diagnostics, and point-of-care testing. We also explore turnaround time and cost considerations, GAS carriage and the interpretation of positive results, and how diagnostic decisions connect with antimicrobial stewardship.

Tune in as we take a practical look at what's changing in Group A strep testing and how laboratories and clinicians can approach these updated recommendations.

This podcast episode is sponsored by Cepheid. The views and opinions expressed by the interviewer in this interview are their own and do not necessarily reflect the position of Cepheid.

Resources

IDSA Clinical Practice Guideline Update on Group A Streptococcal (GAS) Pharyngitis: IDSA 2025 Group A Streptococcal Pharyngitis Guideline

Current Laboratory and Point-of-Care Pharyngitis Diagnostic Testing and Knowledge Gaps: https://pubmed.ncbi.nlm.nih.gov/39688598/

Stay connected with Let's Talk Micro:

Support the podcast:

All episodes of Let’s Talk Micro

Settings

Display

Language

Decides which stations you see first on the home page.

History

Recently played stations and episodes and your latest searches are only stored in this browser.

Notifications

A short notice when a podcast you follow has a new episode. Turn off single podcasts with the bell on their page.

Account

Save favorites – in the app and on the website.

Keyboard shortcuts

/
Open search
Space
Play or pause
← →
In the player: back 15 s, forward 30 s (episodes) · in a row: next tile
↑ ↓
In a row: target within the tile
Home / End
In a row: first or last tile
Esc
Close window or menu
?
This overview
Now playing

Go to station page

Play next

    Add episodes with “Play next” – they play after the current episode.