Live Longer World
- Episodes
- 53
- Released
- monthly
- Latest episode
- Nov 8, 2026
About the podcast
Deep‑dive interviews with frontier scientists on longevity and the biophysics of health. https://livelongerworld.com/
Episodes 53
LED Lights Increase Stress & Disrupt Your Metabolism (And The Hidden Power of Sunlight) | Scott Zimmerman
"LED Lights are the largest experiment in human history!"We evolved under sunlight for millions of years. But today, we spend most of our time indoors under artificial LED lights that are nothing like the sun …
Show notes
"LED Lights are the largest experiment in human history!"
We evolved under sunlight for millions of years. But today, we spend most of our time indoors under artificial LED lights that are nothing like the sun. LEDs are designed for what our eyes can see, not what our biology needs. They lack much of the infrared spectrum found in sunlight. What does this mean for our metabolism, hormones, brain function, and overall health?
Scott Zimmerman is an optical engineer with over 35 years of experience and 80+ patents. He's worked with astrophysicist Bob Fosbury, neuroscientist Glen Jeffery, and melatonin researcher Russel Reiter to understand how sunlight and infrared light influence our cellular energy production and health.
Episode show notes + bonus practical takeaways: https://www.livelongerworld.com/p/szimmerman
He explains:
◼️ Why the real problem with LEDs is not blue light.
◼️ How infrared boosts mitochondria, metabolism, and melatonin.
◼️ How switching lights changed Scott's cortisol and melatonin within minutes.
◼️ Why women, children, and developing fetuses may be more sensitive to LEDs.
◼️ Why red light therapy may be harmful!
◼️ Practical ways to switch to healthier lighting.
TIMESTAMPS:
0:00 Are we overlooking sunlight as a major energy source?
4:50 What LEDs are missing, and why red light panels aren't the solution
6:59 Sunlight extends to 32,000 nm. Why does this matter?
13:03 How infrared light may accelerate cellular energy production
26:17 How UV and infrared work together in our skin
29:00 Blue light isn't the real problem with LEDs!
31:01 He switched on an LED TV. Cortisol rose and melatonin fell within minutes.
54:27 Melatonin isn't just for sleep. It's our oldest antioxidant.
1:01:27 Are women and children more vulnerable to LED lighting?
1:06:33 Sunlight influences brain development in the womb
1:11:40 Could infrared light affect cancer cells?
1:27:20 Your skin isn't just a barrier. It's a hormone factory!
1:33:28 How sunlight can deactivate viruses in the air
1:37:20 Air conditioning and COVID spikes: Is there a connection?
1:47:27 How Red light therapy can backfire
1:54:03 Regulations are eliminating the only healthy light bulbs
1:56:04 A light bulb that mimics sunlight by day and firelight at night
2:10:22 A boy with a severe fungal infection asked to go outside. What happened next?
2:20:58 Why were COVID outcomes so different across skin color and latitude?
2:22:19 Is UV the whole story behind skin cancer? The surprising makeup and sunscreen connection
2:27:01 Does an ice plunge spike cortisol? Scott challenges Andrew Huberman
2:31:58 The mysterious 480nm light signal at dawn and sunset
AASTHA, LIVE LONGER WORLD:
Join 2,700+ for practical health protocols on circadian alignment, light, EMF, and non-toxic living: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
LinkedIn: https://www.linkedin.com/in/aasthajs/
Health products I use: https://www.healthstacked.com/aasthajs
SCOTT ZIMMERMAN:
LinkedIn: https://www.linkedin.com/in/scott-zimmerman-29b7b59/
NIRA Light Bulbs: https://niralighting.myshopify.com/?ref=LIVELONGERWORLD (10% off)
Introducing HEALTH STACKED: https://www.healthstacked.com/
I built the health store I’ve always wanted. Health Stacked is a vetted marketplace of 300+ health and longevity products across 9 categories like sleep, fitness, non-toxic home, lighting & EMF. Products are screened for plastic, PFAS, and 20+ toxins. Inclusion is 100% merit-based.
RELATED PODCASTS:
Your LED Lights Are Fueling Cancer: https://open.spotify.com/episode/4rlB84Aft5skuCw5zkjPeA?si=PWWb72IpT_O2o1eRsqLnyg
Infrared Light Is Exercise For Your Brain: https://open.spotify.com/episode/7ux5aYcssYQdOJR7aQeax0?si=4tfNlDyCTg6VtF0-UMQDlQ
LED Lights Shorten Your LifeSpan (Here's What I Do About It): https://www.livelongerworld.com/p/nontoxicbedroom2
What Farmers Knew Abut Healthy Lighting That We’ve Forgotten: https://www.livelongerworld.com/p/farmersun
Is Cancer Your Body's Defense Mechanism? (How Tumors Trap Toxins & Seed Oils) | Patrick Coles
What if cancer isn't the enemy? What if tumors are actually the body's defense mechanism against toxins, hoarding harmful substances so they don't spread to vital organs? Almost like the body's garbage …
Show notes
What if cancer isn't the enemy? What if tumors are actually the body's defense mechanism against toxins, hoarding harmful substances so they don't spread to vital organs? Almost like the body's garbage collector.But cancer kills so many people. How could it possibly be protective?
Dr. Patrick Coles argues that the body has different layers of defense against toxins. First, the liver, kidneys and fat. As toxins accumulate, he believes the body creates skin growths, cysts and nodules, and eventually tumors as the last toxin storage vaults. He calls this Toxin Sequestration Theory.
Patrick is a physicist and former Staff Scientist at Los Alamos National Laboratory, where he led the near-term quantum computing group. His theory builds on the work of Stephanie Seneff, who's also been on this podcast.
Episode show notes + bonus takeaways: https://livelongerworld.com/p/pcoles
He explains:
◼️The evidence that cancer cells pull in seed oils, heavy metals and microplastics
◼️Why tumors form in certain organs, but almost never in the heart
◼️Why brain tumors may protect against Alzheimer's
◼️Fat as a toxin store, and the risks he sees in rapid weight loss, GLP-1s and fasting
◼️Where he disagrees with Thomas Seyfried: Are cancer cell mitochondria broken or deliberately turned down?◼️His views on chemo, radiation, surgery and immunotherapy, and why he's skeptical of ivermectin and fenbendazole
THANKS TO OUR SPONSOR: TRACED
How do you know what toxic metals you're actually exposed to? Traced uses technology developed at Mount Sinai to analyze a few strands of hair for 15 elements, including heavy metals like lead, arsenic and cadmium. You get a digital report showing possible sources of exposure, with practical guidance to help you reduce your exposure.
Get 20% off at https://traced.life with code LIVELONGERWORLD.
TIMESTAMPS:
00:00 "The purpose of a cancer cell is to store toxins"
00:48 Is cancer a defense mechanism, not a disease?
00:58 Toxin Sequestration Theory (TST) in a nutshell
05:33 The three tiers: detox organs, mini vaults, tumors
08:22 Genetic theory vs. metabolic theory of cancer
11:07 Do cancer cells pull in toxins on purpose?
17:07 Sponsor: Traced hair toxin test
22:27 Why tumors form where they do: lungs, liver, kidneys
26:03 Skin, breast and prostate: the "sacrificial organs"
29:56 Why the brain gets tumors
33:31 Brain tumors and Alzheimer's: the inverse correlation
39:32 Fat tissue, obesity and the right way to lose weight
46:54 Why cancer cells have damaged mitochondria and DNA
52:23 The Warburg effect reinterpreted
57:08 Health Stacked
1:00:02 Chemo, radiation and the remission-rebound pattern
1:05:15 Spontaneous tumor regression
1:08:52 What about surgery?
1:12:22 Fenbendazole, ivermectin and the parasite theory
1:24:36 Calcium, arterial plaque and osteoporosis
1:33:55 Cholesterol, bile and gallstones
1:39:36 Jack Kruse vs. Stephanie Seneff on deuterium
1:46:26 What hair and nails reveal about toxin load
1:51:48 Postpartum hair loss, copper and estrogen
1:56:52 Why he's against iron supplements
2:06:07 UV light, infrared and John Ott
2:15:26 Immunotherapy and bioelectricity
AASTHA, LIVE LONGER WORLD:
Join 2,500+ for practical health protocols on circadian alignment, light, EMF, and non-toxic living: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
LinkedIn: https://www.linkedin.com/in/aasthajs/Health products I use: https://www.healthstacked.com/aasthajs
Dr. Patrick Coles:
Substack: https://patrickcoles.substack.com/
Introducing HEALTH STACKED: I built the health store I’ve always wantedhttps://www.healthstacked.com/
RELATED PODCASTS:
This Hidden Molecule Fuels Cancer | Stephanie Seneff: https://www.youtube.com/watch?v=mlWBorwk1hA&t=2852s
Why Cancer Cells Are Dehydrated | Dr. Gerald Pollack: https://www.youtube.com/watch?v=8jWRl-OwIkI&t=1192s
Harvard Scientist: Your LED Lights Are Fueling Cancer https://www.youtube.com/watch?v=JTwTXTbTQag&t=505s
UCL Neuroscientist: Infrared Light Is Exercise For Your Brain (And It's Slowing Parkinson's) | John Mitrofanis
Our brains run on infrared light. Mitochondria in the brain absorb red and near-infrared light and use it to boost cognition and energy. And mitochondrial dysfunction is a hallmark of Parkinson's, Alzheimer's …
Show notes
Our brains run on infrared light. Mitochondria in the brain absorb red and near-infrared light and use it to boost cognition and energy. And mitochondrial dysfunction is a hallmark of Parkinson's, Alzheimer's and depression.
John Mitrofanis has spent 20 years on the question: If infrared light restores the mitochondria, can it save the brain cells that die in Parkinson's?
John Mitrofanis is a neuroanatomist and Scientific Director of Fonds Clinatec in Grenoble, France, the research center founded by Alim-Louis Benabid, the father of deep brain stimulation. He is also an honorary Professor at University College London's Institute of Ophthalmology, and was Professor of Anatomy at the University of Sydney for over a decade. He is the author of Run in the Light: Exploring Exercise and Photobiomodulation in Parkinson's Disease.
Episode show notes + practical takeaways: https://livelongerworld.com/p/jmitrofanis
He explains:
◼️How infrared light and exercise release the same molecules in the brain, and what BDNF does.
◼️How red and near-infrared light restores mitochondrial function in cells that are dying
◼️How Parkinson’s may begin in the gut
◼️Why current Parkinson’s drugs and deep brain stimulation relieve symptoms but don’t stop the cells from dying
◼️ Red light and sleep: the glymphatic system, brain fog, and why he uses a helmet every day
◼️ Biophotons: the light your cells emit, and why stressed cells and healthy cells emit differently
TIMESTAMPS:
00:00 Cells use light to repair each other
01:00 Red light and exercise work on the same mechanism
02:50 BDNF: the molecule both exercise and light release
06:11 Blue light suppresses melatonin, red light repairs cells
09:00 The Nobel Prize won with red light, and the laser that failed to cure cancer
14:02 What deep brain stimulation actually does
14:54 Why the Parkinson's brain becomes "very, very naughty"
16:17 The beauty of deep brain stimulation, and its limit
18:40 "You apply red light on it." And I laughed
20:57 The light-treated mice kept more dopamine cells alive
23:36 Results of red light to the brain clinical trial
24:16 Is it already too late once symptoms appear?
26:48 Where he disagrees with Glen Jeffery on how deep light penetrates
28:58 Light on the body that reached the brain
31:33 Microvesicles: how cells in trouble call for help
33:12 Does Parkinson's start in the gut?
37:32 Could you skip the device and just sit in the sun?
42:06 What other Parkinson's trials are actually running
44:43 Epilepsy, autism, and cancer
45:56 The cancer evidence that cuts both ways
47:01 What's holding the trials back
48:10 Red light and sleep
49:05 We still don't know why we sleep
01:00:17 He wears the helmet every day
01:02:27 Health Stacked
01:03:15 Red light after a heart attack
01:06:41 670, 810 or 850: which wavelength and how deep
01:11:32 Why 40 hertz seems to be the magic number
01:12:03 Does the time of day matter?
01:16:00 Biophotons: the light inside us
01:22:28 Cancer cells and UV
01:30:22 Biophotons are the frontier
AASTHA, LIVE LONGER WORLD:
Join 2,400+ for practical health protocols on circadian alignment, light, EMF, and non-toxic living: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
LinkedIn: https://www.linkedin.com/in/aasthajs/
HEALTH PRODUCTS I LOVE:
◼️VivaRays 4 in 1 Blue Blockers and UV transmitters: https://vivarays.com/livelongerworld or discount code LIVELONGERWORLD for 10% off
◼️Healthy Home Shop Circadian Bulbs: https://thehealthyhome.shop/livelongerworld for 10% off
Dr. John Mitrofanis:
Profile: https://profiles.ucl.ac.uk/46795-john-mitrofanis
Introducing HEALTH STACKED: https://www.healthstacked.com/
RELATED POSTS:
Boost Mitochondria with Infrared & Sunlight | Glen Jeffery: https://www.livelongerworld.com/p/gjeffery
97 Year Old Brain Scientist: This One Nutrient Prevents Dementia: https://www.livelongerworld.com/p/mcrawford
Why Cancer Cells Are Dehydrated and How Sunlight Hydrates Your Cells | Dr. Gerald Pollack
Most biology textbooks treat the water in our body as background, a solvent that DNA and proteins float around in. But what if a large portion of the energy in our body is actually coming from the water in our …
Show notes
Most biology textbooks treat the water in our body as background, a solvent that DNA and proteins float around in. But what if a large portion of the energy in our body is actually coming from the water in our cells? And what if a disturbance to the structure of that water is a hallmark of cancer and other diseases?
Dr. Gerald Pollack is a Professor of Bioengineering at the University of Washington and one of the few scientists studying what water is actually doing inside our cells. He says water is not the background, it is doing the work. It is a battery, and it is supplying us energy.
Episode show notes + some bonus clips from this episode I only released for premium subscribers, find them: https://livelongerworld.com/p/gpollackHe explains:
◼️ How 99% of the molecules in our body are water molecules, and how water is not just a background solvent
◼️ How water is a battery and gives us energy
◼️ Why every cancer cell is dehydrated with low electrical potential
◼️ The role of infrared light and sunlight on water in our cells
◼️ What builds EZ water: sun, sauna, red light, grounding, juicing, deuterium depleted water, turmeric, holy basil and ghee
◼️ The effect of Hyperbaric oxygen, PEMF and magnets on EZ water
◼️ The link between dementia and EZ water
TIMESTAMPS:
00:00 Water in our cells is central to every disease
00:38 Why almost nobody in biology studies water
01:18 99% of your molecules are water. So why is it treated as filler?
03:41 What water is actually doing inside a cell
07:44 Gilbert Ling, and the book that made his students say all of biology is wrong
11:25 The experiment that started structured water research
14:09 Why cellular water behaves more like a gel than a liquid
16:29 The moment they realized water is a battery
18:29 What charges the water battery, and it isn't food
18:52 Health Stacked
19:43 Is all the water in your cells this kind of water?
23:46 Why he says we shouldn't even call it water
24:57 Does energy actually come from ATP?
27:23 If ATP isn't the fuel, what is it doing there?
30:38 What every cancer cell has in common
33:47 Free things that rebuild the structure of your cellular water
34:48 Turmeric, holy basil and ghee: what his lab found when they tested them
35:11 Morning sun, red light, saunas and grounding
36:22 Hyperbaric oxygen, and how he went looking for it
37:26 PEMF, FSM, and the magnet result that surprised him
41:42 Do WiFi routers shrink the water in your cells?
43:47 The dementia case & water connection
46:32 His answer to the strongest criticism of his work
51:13 Healers, water memory, and the paper he's about to publish
54:36 What anesthesia does to the water in your cells
55:07 What changes if he turns out to be right
57:30 One thing behind almost every disease?
59:07 Why he thinks water drives volcanoes and earthquakes
AASTHA, LIVE LONGER WORLD:
Join 2,400+ for practical health protocols on circadian alignment, light, EMF, and non-toxic living: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
LinkedIn: https://www.linkedin.com/in/aasthajs/
HEALTH PRODUCTS I LOVE:
◼️VivaRays 4 in 1 Blue Blockers and UV transmitters: https://vivarays.com/livelongerworld or discount code LIVELONGERWORLD for 10% off
◼️Healthy Home Shop Circadian Bulbs: https://thehealthyhome.shop/livelongerworld for 10% off
◼️Daylight Computer No-blue screen: https://buy.daylightcomputer.com/livelongerworld for $25 offFull list of health products I use: https://www.healthstacked.com/aasthajs
Dr. Gerald Pollack:
Website: https://www.pollacklab.org/
Books: https://www.pollacklab.org/publications
RELATED POSTS:
Avoiding the sun kills more people than skin cancer: https://www.livelongerworld.com/p/sunsmoking
I covered my WiFi router in foil & reduced EMF radiation 50x: https://www.livelongerworld.com/p/emfphone
Why I Stopped Taking Vitamin D Supplements: https://www.livelongerworld.com/p/vitd
Oxford Biologist: Health is NOT in your Genes | Denis Noble
Oxford physiologist Denis Noble reveals why your genes are not the blueprint for life, why evolution itself works nothing like the selfish gene made us believe, and why the failed promise to cure disease by …
Show notes
Oxford physiologist Denis Noble reveals why your genes are not the blueprint for life, why evolution itself works nothing like the selfish gene made us believe, and why the failed promise to cure disease by reading our DNA points to a completely different understanding of health and aging!
Denis Noble built the first working mathematical model of the heart in 1960 and is one of the founding figures of systems biology. He is a professor at Oxford with a career spent studying how living systems work, and he now argues that the genome is a database the living cell draws on, not the program running the show.
He explains:
◼️Why the Human Genome Project never delivered the cures we were promised
◼️Why your DNA cannot actually predict most disease
◼️The CD analogy: why studying genes tells you nothing about the music of life
◼️His long-running clash with Richard Dawkins and the selfish gene
◼️Why purpose and intelligence run all the way down, from your immune system to a predator hunting its prey
Episode Show Notes: https://livelongerworld.com/p/denisnoble
TIMESTAMPS:
00:00 The Selfish Gene Is Just Not Correct
00:21 What Are Functional Networks, Really?
02:09 Genes Build the Muscles, But Don't Move Them
09:42 Your Genes Are a CD, Not the CD Player
12:11 Can Your DNA Predict Your Disease?
14:23 If Not Genes, How Do We Find Cures?
18:18 Then Does Gene Therapy Even Work?
21:32 Why Scientists Can't Let the Paradigm Go
24:08 What Darwin and Lamarck Actually Said
31:42 Do Animals Choose? Darwin Thought So
38:07 The Finite Monkeys Problem With Evolution
45:15 Inheritance Without Changing Your DNA
49:31 How Do You Actually Reproduce Denis Noble?
50:49 Is the Selfish Gene Right From Evolution's View?
54:45 Answering Jerry Coyne: Isn't DNA the Recipe?
59:51 Who Wrote the Genetic Code?
1:08:22 The Problem of Form: You Can't Get It From Genes
1:12:01 The Mitochondria Accident That Made Complex Life
1:13:05 Why Big Life Needs a Heart
1:17:54 Why Mars Is a Pipe Dream
1:18:45 Mike Levin and the Alignment of the Body
1:21:29 What Does Denis Disagree With Mike Levin On
1:24:59 The Biggest Taboo: Purpose in Biology
1:27:35 Is Consciousness Just Expensive Energy?
1:28:55 What Your Immune System Knows
1:42:01 How Birds at Altitude Prove the Point
1:44:29 Final Thoughts: Life Is More Interesting Than You Think
DENIS NOBLE:
Website: https://www.denisnoble.com/
Books: https://www.denisnoble.com/buy/
AASTHA, LIVE LONGER WORLD:
Newsletter: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
Full list of health products I use: https://www.healthstacked.com/aasthajs
CAMERON, RICCI FLOW NUTRITION:
Newsletter: https://ricciflow.substack.com/
X: https://x.com/ricciflowhealth
Instagram: https://www.instagram.com/ricciflownutrition/
PREVIOUS PODCAST WITH DENIS NOBLE & MICHAEL LEVIN on Biology's Functional Networks, NOT Genes, are key for Longevity: https://www.youtube.com/watch?v=0_Ak-1rbbWg&t=3823s
The Light Doctor: The Link Between LED Bulbs & Cancer That They're Hiding From You!
Circadian scientist Dr. Martin Moore-Ede reveals why the LED bulbs in nearly every home may be driving a rise in breast and prostate cancer, why he calls the light we now live under the tobacco of our time, and …
Show notes
Circadian scientist Dr. Martin Moore-Ede reveals why the LED bulbs in nearly every home may be driving a rise in breast and prostate cancer, why he calls the light we now live under the tobacco of our time, and why the modern fear of the sun may be shortening our lives instead of protecting them!
Dr. Moore-Ede discovered the master circadian clock in the human brain, the suprachiasmatic nucleus, and ran a sleep and circadian research lab at Harvard Medical School for two decades. He has spent 50 years studying how light governs human health, and now argues that the shift to blue-rich LED lighting has created an environment our bodies were never built for.
He explains:
◼️ Why breast, prostate, and colorectal cancer track almost exactly with how much electric light a society uses
◼️ Why melatonin is not the sleep hormone you think it is, and what it really does at 2am
◼️ How LEDs strip out the red and infrared your mitochondria need for energy
◼️ Why the sun exposure data flips skin cancer advice on its head
◼️ Why your children are going short-sighted, and the wavelength that prevents it
◼️ Why the $200 blue-light glasses most people buy block the wrong blue
AASTHA, LIVE LONGER WORLD:
Episode Show Notes: https://livelongerworld.com/p/mmooreede
X: https://x.com/aasthajs
Instagram: https://instagram.com/aasthajs
My health stack: https://www.healthstacked.com/aasthajs
TIMESTAMPS:
00:00 LED Light Is the Tobacco of Our Time
01:33 The Connection Between Cancer and LED Lighting
04:05 Why Hormone-Driven Cancers Are Hit the Hardest
07:49 Is There a Link to Glioblastoma?
08:14 Why Melatonin Is Not the Sleep Hormone
11:40 There Is No Blue Light in Nature After Sunset
15:58 We Live in Junk Light, Just Like Junk Food
17:21 What Wavelengths Are LEDs Actually Missing?
20:44 The Infrared We Lost When We Banned Incandescents
22:52 The Two Ways LEDs Are Harming You
30:05 Health Stacked
30:56 White vs Yellow Light: Why It's the Wrong Question
33:59 Lux, Lumens, and a 100-Year-Old Mistake
38:27 What LED Light Does to Your Heart and Immune System
40:44 Why Regularity Matters as Much as the Light Itself
43:07 The Camping Study That Reset Everyone's Body Clock
49:56 Sunlight vs Skin Cancer: We Have It Backwards
53:03 The 450 vs 480 Spike Almost No One Gets Right
59:52 Why Life Evolved to Run on Blue Light
01:03:13 Melanopsin: Your Body's Blue Detector
01:08:28 Do Melatonin Supplements Actually Do Anything?01:12:19 Why the Wrong Side of a Time Zone Can Kill You
01:15:37 Is There Something Special About Dawn?
01:17:12 Light and the Early Onset of Puberty
01:20:53 The Aggressive Kid Who Changed When the Lights Did
01:21:51 Should You Replace Your Windows?
01:24:00 Do not wear sunglasses in the morning!
01:26:44 What About Daytime Lighting?
01:27:41 Do Blue-Light-Blocking Glasses Work at Night?01:31:20 Take Your Lighting Into Your Own Hands
PRODUCTS I USE FOR BETTER CIRCADIAN RHYTHM:
◼️VivaRays 4 in 1 Blue Blockers: https://vivarays.com/livelongerworld or code LIVELONGERWORLD for 10% off
◼️Healthy Home Shop Circadian Bulbs: https://thehealthyhome.shop/livelongerworld for 10% off
◼️Daylight Computer No-blue screen: https://buy.daylightcomputer.com/livelongerworld for $25 off
◼️Chroma Circadian-Aligned Desk Lamp: https://getchroma.co/photonsfromaastha and code LIVELONGERWORLD for 10% off
Full list of health products I use: https://www.healthstacked.com/aasthajs
Dr. Martin Moore-Ede:
Website: https://thelightdoctor.com/
Book: THE LIGHT DOCTOR: Using Light to Boost Health, Improve Sleep, and Live Longer: https://amzn.to/4yrwWWu
HEALTH STACKED, the trusted longevity marketplace: https://www.healthstacked.com/
RELATED POSTS:
Avoiding the sun kills more people than skin cancer: https://www.livelongerworld.com/p/sunsmoking
Your Lights are Wrecking your Sleep (Here’s What I Use): https://www.livelongerworld.com/p/redlights
Your Screens Are Keeping You Awake: 60 second fix: https://www.livelongerworld.com/p/redphone
97 Year Old Brain Scientist: This One Nutrient Prevents Dementia | Dr. Michael Crawford
97-Year-Old Brain Scientist Professor Michael Crawford reveals why the human brain has been physically shrinking for thousands of years, why he believes it was DHA, an omega-3 fat from the sea, and not your …
Show notes
97-Year-Old Brain Scientist Professor Michael Crawford reveals why the human brain has been physically shrinking for thousands of years, why he believes it was DHA, an omega-3 fat from the sea, and not your genes, that built human intelligence, and why the official advice to limit fish in pregnancy may be harming an entire generation of babies!
Professor Michael Crawford is Director of the Institute of Brain Chemistry and Human Nutrition and a visiting professor at Imperial College London, with more than 300 published papers and the 1972 work that first linked DHA to the evolution of the human brain. At 97, he is still sharp, still publishing, and still arguing that modern nutrition has neglected the one organ that makes us human.
He explains:
◼️ Why the brain physically cannot work without DHA, full stop
◼️ Why it was DHA, not DNA, that shaped the human brain
◼️ Why he says the FDA is wrong about limiting fish in pregnancy
◼️ How seed oils quietly crowd this fat out of your brain cells
◼️ Whether dementia and Alzheimer's actually begin in the womb
◼️ Why humans could only have evolved big brains beside the sea
◼️ How chicken and eggs lost almost all of their brain fat
◼️ Why he believes DHA works like a semiconductor in your neurons
Episode Show Notes: https://livelongerworld.com/p/mcrawford
Find me on X: https://x.com/aasthajs
Instagram: https://instagram.com/aasthajs
My health stack: https://www.healthstacked.com/aasthajs
TIMESTAMPS:
00:00 The Brain Food We Stopped Eating
00:32 "Your Brain Won't Work Without DHA. That's just full stop"
04:04 It Wasn't DNA That Made Us Human
06:50 How the Eye Built the Brain
08:00 Why Carnivores Are Sharper Than Herbivores
11:35 The Flowering Plant That Invented Pregnancy
14:22 The Placenta: An Organ Built From One Fatty Acid
15:35 Why Arachidonic Acid Is Wrongly Demonized
18:18 More Astrocytes Than Neurons: Who Really Runs the Brain
21:39 Health Stacked
22:38 DHA vs Arachidonic Acid: Two Different Origins
25:21 How the Fetus Hoards DHA and Rejects the Rest
30:31 Are Seed Oils Actually Starving Your Brain?
32:24 Why the FDA is wrong about Fish in Pregnancy
37:50 Do Fish Oil Supplements Work?
44:15 The Lack of Fish in Pregnancy is causing ADHD and Austism
50:10 Why Governments Only Care About Body Size, Not Brains
52:00 "A Race of Morons": The Warning From 1972
55:04 Does Dementia Actually Begin in the Womb?
59:16 Does the Father's Nutrition Matter Too?
59:40 The Importance of Arachidonic Acid that Infant Formula Leaves Out
01:02:24 How Often You Should Actually Eat Seafood
01:04:05 Can Vegetarians and Vegans Get Enough?
01:05:04 Can Genetics Let You Skip Seafood? The India Case
01:08:00 Why Humans Could Only Have Evolved Beside the Sea
01:11:55 Farming the Sea: What Japan Figured Out
01:17:22 The Collapse of DHA in Chicken and Eggs
01:20:52 Why Corn-Fed Everything Is Lower in DHA
01:22:32 The Semiconductor Theory of the Brain, Explained
01:27:20 What Dr. Crawford's Vision Is Like at 97 years old
01:28:39 The Rare Double-DHA Molecule in Your Retina
01:29:23 Where Dr. Crawford Lands on Saturated Fat
01:31:09 His Advice to Young Scientists: Challenge Everything
01:32:07 Closing: Why This Is a Three-Generation Emergency
AASTHA, LIVE LONGER WORLD:
Join 2,100+ for practical health protocols on circadian alignment, light, sleep, non-toxic living and more: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
Dr. Michael Crawford:Book The Shrinking Brain: https://amzn.to/4vEJiZ3Introducing
HEALTH STACKED: https://www.healthstacked.com/
I built the health store I’ve always wanted. Health Stacked is a vetted marketplace of 500+ health and longevity products across 12 categories like sleep, fitness, non-toxic home, lighting & EMF, and more.
Products are screened for plastic, PFAS, and 20+ toxins. Inclusion is 100% merit-based. And every product has been hand-picked by me.
MIT Scientist: This Hidden Molecule Fuels Cancer (And It's In Your Supplements) | Stephanie Seneff
Is a hidden molecule in your food and water silently fueling cancer, Alzheimer's, and Parkinson's? Could the supplements you trust every day be making it worse?Dr. Stephanie Seneff is a senior research …
Show notes
Is a hidden molecule in your food and water silently fueling cancer, Alzheimer's, and Parkinson's? Could the supplements you trust every day be making it worse?
Dr. Stephanie Seneff is a senior research scientist at MIT (published in PNAS, Frontiers, FASEB) with a career studying nutrition, biology, and toxicology.
In this conversation, she explains why deuterium — a heavier form of hydrogen — may be the most underrated driver of chronic disease, why cancer might be the body's repair response to deuterium-damaged mitochondria, and why most supplements may backfire.
We discuss:
◾ Why deuterium may be the most important molecule you've never heard of
◾ How glyphosate stops your body from clearing deuterium
◾ The two supplements you should stop taking immediately
◾ Why she says: "I don't believe in supplements"
◾ Why chemo may be working backwards on cancer
◾ How to make your gut produce low-deuterium water
◾ The folic-acid-in-pregnancy and autism connection
◾ Why she drinks deuterium-depleted water every day
This is Dr. Seneff's second appearance on Live Longer World. Her first episode on glyphosate is linked below.
Episode Show Notes: https://livelongerworld.com/p/sseneff2
Find me on X: https://x.com/aasthajs
My health stack: https://www.healthstacked.com/aasthajs
TIMESTAMPS:
0:00 Why deuterium might be the most important molecule you've never heard of
5:09 The hidden reason processed food is wrecking your health
7:25 How deuterium breaks your mitochondria
11:02 Glyphosate stops your body from rationing deuterium (and the osteoporosis link)
18:23 Health Stacked
19:07 No one is connecting gut health to deuterium, until now
22:45 The two nutrients that help your gut clear deuterium
25:29 Methylation, melatonin, and protecting your mitochondria
33:14 Why melatonin supplements don't actually work
34:08 The two supplements you should stop taking immediately
38:06 How to make your gut produce low-deuterium water
41:12 How glyphosate suppresses your MTHFR gene
43:21 Why folate supplementation is a problem
45:06 "I don't believe in supplements", Stephanie's case against them
46:02 Why she's suspicious of fish oil
47:47 The folic-acid-in-pregnancy and autism connection
52:37 How glyphosate is quietly causing bone problems
56:22 Inflammation is really a deuterium problem
1:01:25 Gerald Pollack's EZ water and how your cells expel deuterium
1:04:59 Why breast milk is low in deuterium
1:09:03 Cancer's real job: repairing your mitochondria (and why chemo may be a mistake)
1:23:14 How deuterium-depleted water may help heal cancer
1:26:57 Deuterium and Parkinson's: how plaque traps it
1:30:37 How to fight Parkinson's
1:33:55 Why Stephanie drinks deuterium-depleted water every day
1:36:37 What glyphosate does to your sulfation system
1:38:38 How grounding reduces deuterium
1:39:42 Jack Kruse on glyphosate and melanin
1:40:08 Are seed oils high in deuterium?
1:45:05 Does where you live (and sunlight) affect your deuterium?
1:47:05 Practical tips to manage your deuterium load
Dr. STEPHANIE SENEFF:
Website: https://stephanieseneff.net/
X: https://x.com/stephanieseneff
AASTHA, LIVE LONGER WORLD:
Join 2,000+ others for practical health protocols on circadian alignment, light, sleep, & non-toxic living: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
Introducing HEALTH STACKED: https://www.healthstacked.com/
I built the health store I’ve always wanted. Health Stacked is a vetted marketplace of 500+ health & longevity products across 12 categories like sleep, fitness, non-toxic home, lighting & EMF, and more. Products are screened for plastic, PFAS, and 20+ toxins. Inclusion is 100% merit-based. And every product has been hand-picked by me.
RELATED EPISODES:
Glyphosate Toxicity & Deuterium's Role in Cancer, Celiac, Aging | Dr. Stephanie Seneff: https://open.spotify.com/episode/4HFmNT0fLCckXvrC1XRSFt?si=cSv7wuPPTm2wE5YSMY2L3w
New Theory of Aging: Humans vs. Pathogens
The standard “wear and tear” story of aging may be incomplete. Dr. Peter Lidsky—a virologist and evolutionary biologist argues that aging is programmed. He says aging can be an adaptive strategy for controlling …
Show notes
The standard “wear and tear” story of aging may be incomplete. Dr. Peter Lidsky—a virologist and evolutionary biologist argues that aging is programmed. He says aging can be an adaptive strategy for controlling pathogens, a concept he calls the “pathogen control hypothesis.”
In this episode, we dig into the evidence behind this idea, the immune system in aging, and what his theory means for longevity interventions.
Episode Show Notes: https://livelongerworld.com/p/plidskyFind me: https://x.com/aasthajs My longevity products: https://www.livelongerworld.com/p/2024TIMESTAMPS:0:00 — Aging ≠ Wear-and-Tear
3:44 — The Case for Programmed Aging
8:48 — Why Program Aging at All?
11:09 — The Pathogen-Control Hypothesis
14:26 — Why We Get “Sick Time”
24:37 — Rising Lifespans, Explained
27:36 — Bowhead Whales’ Longevity Edge
31:15 — Why Lone Animals Don’t Live Forever
34:00 — Planaria: The “Immortal” Worm
35:00 — Do Infections Speed Up Aging?
36:46 — When Immunity Starts to Slide
38:17 — Why Fertility Has a Deadline
42:49 — Extending Life via the Immune System
1:00:35 — How Honey Bees Rejuvenate
1:10:50 — Can We Tackle Aging? Healthspan to 90s+AASTHA, LIVE LONGER WORLD:X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/Instagram: https://www.instagram.com/aasthajs/Peter Lidsky: https://www.cityu.edu.hk/bms/profile/peterlidsky.htmRELATED:Dr. Geoffrey West | Scaling Laws in Longevity & Aging: https://youtu.be/T67U8IK_1RU?si=ajq5AbjM6ufBQ7WfDr. David Gems | Hyperfunction & Programmatic Theory of Aging & Critique of Hallmarks of Aging: https://youtu.be/rLD-8UhHEZM?si=R_x_mLguTAKfdXtQDr. Bjorn Schumacher | DNA Damage & Aging, p53 & Cancer, and DNA repair in Reproductive Cells: https://youtu.be/kjQ-SwEP1bo?si=G2mEtNZs1O7TsLKe
Optimize Cancer Therapy Using Evolution | Michael Levin & Robert Gatenby
“We can use the rule of evolution to optimize cancer therapy. The standard practice is that any therapy is given at maximum tolerated dose continuously until progression. It's almost a mantra that they have …
Show notes
“We can use the rule of evolution to optimize cancer therapy. The standard practice is that any therapy is given at maximum tolerated dose continuously until progression. It's almost a mantra that they have. Evolutionarily, you could hardly do it worse.” The current treatments on cancer do not account for how evolution works. Dr. Robert Gatenby has been studying evolutionary and game theory dynamics in the progression of cancer. He established the first cancer biology and evolutionary program in the U.S. We can leverage this evolutionary information to provide more effective cancer treatment, which he discusses in this episode. Dr. Michael Levin is my co-host.Episode Show Notes: https://livelongerworld.com/p/rgatenbyFind me: https://x.com/aasthajs My longevity products: https://www.livelongerworld.com/p/2024TIMESTAMPS:0:00 – Cancer as Tissue Damage, Not Just Mutations8:48 – How Evolution Supercharges Cancer Cell Fitness11:04 – Debunking the “Primitive Cell” Myth12:06 – The Herd Mentality of Cancer Cells14:57 – Why Cancer Dynamics Go Beyond the Genome22:27 – Networks and Information Flow Inside Cells26:56 – Shared Goals: The Secret to Cellular Cooperation29:55 – Genome = Hardware, Information = Software36:26 – Healthy vs. Cancer Cells: Competing Information Systems39:05 – Evolution Turns Harsh After Reproduction41:03 – How Cancer Rewrites Its Own Information Playbook43:07 – Adaptive Therapy: A Patient’s Guide50:45 – The Limits of Adaptive Therapy53:12 – Hunting for Better Cancer Biomarkers55:11 – The Tumor Microenvironment’s Hidden Role59:42 – Why We Must Look Beyond Genetic DataAASTHA, LIVE LONGER WORLD:X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/Instagram: https://www.instagram.com/aasthajs/LINKS:Michael Levin: https://x.com/drmichaellevinRobert Gatenby: https://www.moffitt.org/inspiring-stories/dr.-gatenbys-storyEpisode Show Notes: https://livelongerworld.com/p/rgatenbyALSO WATCH:The First Cancer Cell: A Revolution in Early Detection | Michael Levin & Azra Raza: https://open.spotify.com/episode/7yW6ZVVdQkboWpldUZyenD?si=obYEC22NSsSyy7j09JBf7QKeto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=Yz9CQ-wNQ3WdcwjKw3lXGwWhy Viruses Could Be the Cause of Chronic Disease | Dr. Paul Ewald: https://open.spotify.com/episode/2OdYInlzTy2zG3Mi6TgADY?si=BtishVk_R-28K2KypODIog
Live to 130 with new mitochondria | Tom Benson, Mitrix Bio on Mitochondrial Transplantation
Mitochondria might be one of the most important organelles inside our cells. Best known as the cell’s powerhouse, they don’t just make energy; they regulate metabolism, control cell death, drive immune …
Show notes
Mitochondria might be one of the most important organelles inside our cells. Best known as the cell’s powerhouse, they don’t just make energy; they regulate metabolism, control cell death, drive immune function, and may even be the reason multicellular life exists at all!
It’s no surprise they’re implicated in nearly every major disease, from heart disease and cancer to neurodegeneration, especially as they decline with age. What if we could slow or even reverse that decline by giving cells fresh, healthy mitochondria? That’s the promise of mitochondrial transplantation—a groundbreaking approach Mitrix Bio is pioneering.
In this episode, I talk with CEO Tom Benson about the science, the potential, and the early results from people already lining up for their trial.
Episode Show Notes: https://livelongerworld.com/p/tbenson
Find me: https://x.com/aasthajs
My longevity products: https://www.livelongerworld.com/p/2024
TIMESTAMPS:
00:00 - Injecting new mitochondria into your body
01:39 - Mitochondria’s evolutionary role in aging
04:35 - What happens to old mitochondria?
06:18 - Why humans live longer than other animals
11:30 Why cardiovascular disease is #1 killer
12:30 - Why does the brain remain sharp with age?
15:30 Why does energy decline after age 30?
19:04 Why doesn’t the body correct mitochondrial mutations?
22:42 Mitochondrial defects in children
24:14 Diagnostics for mitochondrial health
27:36 Mitochondrial DNA is eternal
33:18 Where does mitochondria come from in mitochondrial transplantation?
34:59 Growing mitochondria in a bioreactor
39:07 How neurons grow their mitochondria
40:52 Mitochondrial theory of cancer
44:23 Mitochondria and psychobiology
48:32 Chemotherapy and radiation damage mitochondria
50:38 Evidence that mitochondrial transplantation works
56:06 Caloric restriction, sauna, sunlight, and mitochondria
1:00:01 Mitochondria and races
1:02:57 Why stop at 130 years old?
1:04:48 Why might this not work?
1:10:03 Volunteers for Mitrix trial
AASTHA, LIVE LONGER WORLD:
X: https://x.com/aasthajs
Newsletter: https://livelongerworld.com/
Instagram: https://www.instagram.com/aasthajs/
Mitrix Bio:
https://mitrix.bio/
Tom Benson: https://mitrix.bio/team/tom-benson/
RELATED:
New Spin to the Free Radical Theory of Aging: https://www.livelongerworld.com/p/ros
Keto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=biOOH1e5RpeZduLJv2fPHw
Boost Mitochondria with Sunlight and Infrared light: https://open.spotify.com/episode/1jGfhzX1P245LU2kLwgHTq?si=yPOC3bViRnmOUeR-P0jeWA
Detect the First Cancer Cell | Michael Levin & Azra Raza
Can we detect cancer so early such that we find the very first cell of cancer? Not just stage 1 cancer, but the first cell of cancer.In this episode, Dr. Michael Levin and I speak with Dr. Azra Raza. She is an …
Show notes
Can we detect cancer so early such that we find the very first cell of cancer? Not just stage 1 cancer, but the first cell of cancer.
In this episode, Dr. Michael Levin and I speak with Dr. Azra Raza. She is an oncologist pioneering early detection of cancer using electric signals. So far, our best solution to curing cancer has been to detect it early, and she wants to take this further, by nipping cancer at the very first cell.
Her story with cancer is also deeply personal as she lost her husband to the disease. You can see in the episode how much she cares about solving cancer through early detection, and how aggrieved she is about the fact that not only have we made zero progress on cancer in the last 100 years, but doctors are also not focused on cancer prevention.
Dr. Raza is also the author of the book The First Cell: And the Human Costs of Pursuing Cancer to the Last.
Episode Show Notes: https://livelongerworld.com/p/araza
Find me: https://x.com/aasthajs
My longevity products: https://www.livelongerworld.com/p/2024
TIMESTAMPS:
0:00 New theory of cancer
1:45 What causes cancer?
5:39 Hybrid cells in cancer
11:16 Why do cancer cells become immortal?
14:14 Detecting the first cell of cancer
17:09 Stress causes cancer cells to fuse
21:40 Cancer drugs don’t work universally
25:54 Personalization of early cancer detection
29:29 Detect cancer early using electrics
35:46 Anguish of cancer patients
39:06 Cancer progress hasn’t moved in 100 years
44:04 Doctors don’t think of cancer prevention
46:54 First Cell Therapeutics - Azra’s company
50:55 What is the first cell stage of cancer?
54:55 Advice for cancer patients
AASTHA, LIVE LONGER WORLD:
Twitter: https://x.com/aasthajs
Newsletter: https://livelongerworld.com/
Instagram: https://www.instagram.com/aasthajs/
LINKS:
Michael Levin: https://twitter.com/drmichaellevin
Azra Raza: https://azraraza.com/
Azra Raza book The First Cell: https://amzn.to/4jGJzoJ
Episode Show Notes: https://livelongerworld.com/p/araza
RELATED EPISODES:
Keto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=gboyPAiLQrqg-y5YEKQiQQ
Why Viruses Could Be the Cause of Chronic Disease | Dr. Paul Ewald: https://open.spotify.com/episode/2OdYInlzTy2zG3Mi6TgADY?si=Gnbg7efNSy21bS3q0c23jg
Hidden Viruses Cause Cancer & Alzheimer's | Dr. Paul Ewald
What if chronic diseases like cancer and Alzheimer’s are caused by infections we’ve overlooked? We assume chronic disease is caused by genetics and / or lifestyle. However, evolutionary biologist Dr. Paul Ewald …
Show notes
What if chronic diseases like cancer and Alzheimer’s are caused by infections we’ve overlooked?
We assume chronic disease is caused by genetics and / or lifestyle. However, evolutionary biologist Dr. Paul Ewald says latent viruses and pathogens play a critical hidden role in many diseases.
For example, we already know that Human Papillomavirus (HPV) causes cervical cancer. And research indicates how the EBV virus shows up in Multiple sclerosis, and chlamydia pneumonia shows in Alzheimer’s. Deeper investigation into viruses and disease is warranted and will help with better diagnosis and treatment.
Dr. Paul Ewald is also the author of Plague Time: The New Germ Theory of Disease, and Evolution of Infectious diseases. Episode Show Notes: https://livelongerworld.com/p/pewaldFind me: https://x.com/aasthajs My longevity products: https://www.livelongerworld.com/p/2024TIMESTAMPS:0:00 Role of infection in chronic disease is neglected
2:40 Role of viruses in Alzheimer’s
10:50 Connections between Alzheimer’s, diabetes, cardiovascular disease
15:57 Genes cannot explain the full reason for disease
20:47 Strong association between Alzheimer’s, chlamydia pneumonia, and APOE4
28:16 Multiple sclerosis and EBV virus
35:08 Latent viruses may in fact be active & cause cancer
41:41 Sexually- transmitted pathogens correlated with cancer
46:50 Viruses that cause cancer (EBV & breast cancer)
53:09 Hodgkin’s lymphoma and virus
57:15 Stanford study showing EBV as leading cause of MS
1:00:19 Do viruses attack the mitochondria and cause cancer
1:01:38 Glioblastoma and virus / antiviral treatment
1:07:07 Virus vs. oncogenes causing cancer
1:14:17 Breast cancer BRAC1 mutations & virus association
1:15:59 Vaccines against viruses
1:17:56 Practical steps if you test positive for infectious viruses
1:24:57 Could cancer relapse be due to persistent virus
1:27:48 Protect the immune system
1:29:38 Areas Dr. Ewald is excited aboutAASTHA, LIVE LONGER WORLD:X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/Instagram: https://www.instagram.com/aasthajs/PAUL EWALD LINKS:Plague Time: The New Germ Theory of Disease: https://amzn.to/3FXjOSuEvolution of Infectious diseases: https://amzn.to/3FYaqOvEpisode Show Notes: https://livelongerworld.com/p/pewaldALSO WATCH:Keto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=biOOH1e5RpeZduLJv2fPHw
Michael Levin & Pamela Lyon | Rethinking Cognition for Longevity
What if our cells have memory and cognition, which changes how medicine is done?In this conversation with Dr. Pamela Lyon and Dr. Michael Levin, we discuss:- Cognition and creativity is not merely associated …
Show notes
What if our cells have memory and cognition, which changes how medicine is done?
In this conversation with Dr. Pamela Lyon and Dr. Michael Levin, we discuss:
- Cognition and creativity is not merely associated with the brain and nervous system
- Implications of this view of cognition for regenerative medicine and longevity
- Is stress response the source of our creativity?
Episode Show Notes: https://livelongerworld.com/p/plyon
Find me: https://x.com/aasthajs
My longevity products: https://www.livelongerworld.com/p/2024
TIMESTAMPS:
0:00 Intro, Basal cognition
1:00 Our view of cognition is incorrect
8:50 What does biology have to say about cognition?
12:12 Cognition in xenobots
14:20 Cognition and cooperation in microbes
30:03 Bioelectricity and cognition
33:58 Is stress response the source of our creativity?
43:27 Mike’s paper: Stress-sharing as a cognitive glue
47:31 Implications of cognition not only being associated with brain
56:55 Cognition in AI
1:02:33 View of cognition in the East
AASTHA, LIVE LONGER WORLD:
Twitter: https://x.com/aasthajs
Newsletter: https://livelongerworld.com/
Instagram:https://www.instagram.com/aasthajs/
LINKS:
Michael Levin: https://twitter.com/drmichaellevin
Pamela Lyon: https://www.adelaide.edu.au/directory/pamela.lyon#
Episode Show Notes: https://livelongerworld.com/p/plyon
ALSO WATCH:
Michael Levin & Denis Noble on What Biology Needs to Advance Longevity: https://open.spotify.com/episode/49WaTa4Vl67FU4zjjX1H6F?si=x1rjzVocS2OjSVdxpzNt5g
Boost Mitochondria with Sunlight & Infrared light | Glen Jeffery
We’re only just waking up to the benefits of sunlight and red light for mitochondrial health, lowering blood glucose, and potentially treating Parkinson’s disease and cancer.Dr. Glen Jeffery is at the leading …
Show notes
We’re only just waking up to the benefits of sunlight and red light for mitochondrial health, lowering blood glucose, and potentially treating Parkinson’s disease and cancer.
Dr. Glen Jeffery is at the leading edge of this research.
We discuss:
- Health benefits of sunlight and red light
- Harmful effects of blue light & LEDs
- In the 2nd half of the podcast, I ask him rapid fire practical questions that everyone wants to know about light, ranging from how much sunlight should one get to what time of day is best for infrared light exposure.
Episode Show Notes: https://livelongerworld.com/p/gjeffery
Find me: https://x.com/aasthajs
TIMESTAMPS: 0:00
Intro
0:59 Light impact on public health
3:08 Light research is understudied, mitochondria is impacted by light
6:05 Red and blue light impacts on mitochondria
8:25 Benefits of red light - wound healing, lower glucose
15:09 Are there downsides to red light?
16:59 Does time of day impact red light benefits?
22:05 Red light and cancer
26:00 Blue light is making you pre-diabetic
37:46 n=1 light experiments
39:22 Mitochondria & Longevity
46:21 “Sunlight offers a unique package”
Rapid fire questions:
53:40 Is sunlight good enough for red light?
55:10 How much sunlight do we need?
56:07 When should you get sunlight?
56:55 Should you worry about afternoon sunlight?
58:57 Can you get sunlight on cloudy days?
59:38 Does sunscreen mitigate benefits of sunlight?
1:00:12 Should you not wear caps and sunglasses in sunlight
1:01:43 Clothing and sunlight
1:05:52 Sunlight through window?
1:06:16 Are blue light blocking glasses helpful? (see 1:19:31 for more context)
1:08:17 Do Artificial sunlight lamps work?
1:08:51 What wavelength red light is the best?
1:10:56 Time in front of red light device
1:12:41 Body exposure to red light
1:15:37 Lighting at home at night
1:19:31 Differences in blue light for mitochondria vs. circadian biology
1:24:18 Stop using LEDs
1:25:24 Does light impact the bioelectrics of the mitochondria?
1:26:55 Mitochondria in melatonin mop up ROS
1:31:29 Benefits of fire light?
1:35:33 Open questions on light and health
1:37:28 Support Live Longer World
AASTHA, LIVE LONGER WORLD:
X: https://x.com/aasthajs
Newsletter: https://livelongerworld.com/
Instagram: https://www.instagram.com/aasthajs/
DR. GLEN JEFFERY:
Bio page: https://profiles.ucl.ac.uk/7465-glen-jeffery/publications
ALSO WATCH:- Keto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=rHlCwLVqQHqiOB7yTVBtgQ
Keto Diet & Metabolic Therapy for Cancer | Dr. Thomas Seyfried
Dr. Thomas Seyfried challenges the existing paradigm that says cancer is a genetic disease. He says that instead cancer is caused by damage to the mitochondria. Understanding this completely overturns the …
Show notes
Dr. Thomas Seyfried challenges the existing paradigm that says cancer is a genetic disease. He says that instead cancer is caused by damage to the mitochondria. Understanding this completely overturns the management and prevention of cancer.
He is a Professor of biology, genetics, and biochemistry at Boston College. He has over 150 peer-reviewed publications and is also the author of books such as, ‘Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer’.
WE DISCUSS:
- Why cancer is not a genetic disease
- Why cancer is a metabolic disease originating from damage to the mitochondria
- How metabolic therapy, management of glucose and glutamine, can be used to manage cancer
- His December 2024 paper outlining a proposal for ketogenic metabolic therapy in glioblastoma
Episode Show Notes: https://livelongerworld.com/p/tseyfried Find me: https://x.com/aasthajs
TIMESTAMPS: 0:00 Cancer is not a genetic disease
5:04 Origins of somatic mutation theory of cancer
8:04 Mitochondrial damage causes cancer
13:42 Is mitochondrial dysfunction involved in every cancer
16:14 Mitochondria in cancer cells ferment
21:52 Target glucose and glutamine to manage cancer
28:51 Hyperbaric Oxygen therapy for cancer
31:04 December 2024 study: Role of glutamine in cancer
33:35 Can metabolic therapy be done at any stage of cancer
36:44 Combine chemotherapy with metabolic therapy
38:05 Drugs to target glutamine
40:30 People will say “I want metabolic therapy”
44:04 “Failure to understand biology”
47:48 National Cancer Institute’s take on Dr. Seyfried’s theory
49:34 Why does Peter Attia think cancer is a genetic disease
53:09 “I think about this 24/7; we’re right!”
55:56 Glioblastoma treatment protocol study
59:22 Resistance to breakthrough ideas in science
1:01:40 Radiation fuels cancer!
1:04:52 Current standard of care is responsible for poor survival rate in glioblastoma
1:07:14 Metabolic therapy for epilepsy, Parkinson’s, Alzheimer’s
1:12:22 How to prevent cancer
1:13:49 Young, healthy individuals in their 20s, 30s with cancer
1:15:05 Resources on following metabolic therapy
1:17:43 How to support Dr. Seyfried’s research
1:18:51 New cancer questions Dr. Seyfried is researching
1:21:32 Closing thoughts AASTHA, LIVE LONGER WORLD: X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ DR. THOMAS SEYFRIED: X: https://x.com/tnseyfried Bio page: https://www.bc.edu/bc-web/schools/morrissey/departments/biology/people/faculty-directory/thomas-seyfried.htmlCancer as a Metabolic disease book: https://amzn.to/3WBF31D
RELATED EPISODES:
Denis Noble & Michael Levin | What Biology needs to Advance Longevity
Denis Noble and Michael Levin - two great minds in biology come together on Live Longer World. Denis Noble is a renowned biologist and pioneer in systems biology, known for his groundbreaking work on the …
Show notes
Denis Noble and Michael Levin - two great minds in biology come together on Live Longer World. Denis Noble is a renowned biologist and pioneer in systems biology, known for his groundbreaking work on the electrical activity of the heart and his influential contributions to the understanding of biological systems. Denis is an advocate for taking a systems integrative approach to biology, as opposed to the reductionist gene-centric view that has dominated the field due to Neo-Darwinism.
The gene-centric view has failed us in advancing progress on many diseases, and we need to now take a systems based approach focused on functional networks within biological systems.
Michael Levin is an American developmental and synthetic biologist at Tufts University, where he is the Vannevar Bush Distinguished Professor. His research is focused on bioelectricity and he is my co-host for this podcast. We discuss: - DNA is not the blueprint of life - Why biology’s reductionist approach is flawed - The errors in Neo-Darwinism - Epigenetic inheritance - How to advance the cure of diseases Episode Show Notes: https://livelongerworld.com/p/dnoble Find me: https://x.com/aasthajs TIMESTAMPS: 0:00 Denis as Mike Levin’s hero
0:10 Denis’s journey to systems biology; cell voltage is a global property of the cell
3:45 Advice to young researchers pursuing systems biology
7:00 “Absolutely everything is wrong with Neo-Darwinism”
14:10 Epigenetic inheritance
19:12 Genetic vs. other information used by organisms
23:48 Biology textbooks have to expand beyond DNA in 50 years
25:03 Epigenetic processes are ubiquitous
28:58 If not DNA, what is the blueprint of life
36:15 Rewriting biology textbooks is fundamental
39:57 “A lot of time has been wasted” (in biology)
46:52 Darwin on the “Origin of Species”
55:38 “Unfortunate that Philosophy and science have diverged”
1:00:31 Importance of Functional networks; DNA does not predict disease AASTHA, LIVE LONGER WORLD: Twitter: https://x.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ LINKS: Michael Levin: https://twitter.com/drmichaellevin Denis's book Dance to the Tune of Life: https://a.co/d/3hvh5JW Episode Show Notes: https://livelongerworld.com/p/dnoble
Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8?si=WrQ_iI8ABbG6eibm
Michael Levin & Mustafa Djamgoz | Bioelectricity and Cancer
This interview is part of my series with Dr. Michael Levin where we interview significant people in the history of developmental bioelectricity. Dr. Mustafa Djamgoz was one of the first people to study the role …
Show notes
This interview is part of my series with Dr. Michael Levin where we interview significant people in the history of developmental bioelectricity. Dr. Mustafa Djamgoz was one of the first people to study the role of ion channels and bioelectricity in cancer, which he initially documented in a 1995 paper. His research showed that there was an uptake in voltage-gated sodium channels in all types of cancer metastasis, except prostate cancer, highlighting the significant role of studying ion channels in cancer. Simply put, the spread of cancer cells is linked to increased activity in sodium ion channels, which regulate electrical currents in our cells. Episode Show Notes: https://livelongerworld.com/p/mdjamgoz Find me: https://x.com/aasthajs Background on the bioelectricity series & 1st episode with Dr. Richard Nuccitelli: https://youtu.be/DtUqOwTRvz0?si=3OJryM0yJjzfQtfo TIMESTAMPS: 0:00 Playing with radios at age 17 to bioelectricity cancer research 4:31 Advice for young people entering bioelectricity 9:02 Biophysics and Cancer neuroscience 17:55 Role of bioelectricity in cancer 27:02 Cancer metastasis and ion channels 28:49 Sodium channel uptake and cancer invasiveness 36:59 Ranolazine, potential anti-metastatic drug 43:45 Funding for bioelectricity cancer research 50:21 Advice for cancer patients AASTHA, LIVE LONGER WORLD: Twitter: https://x.com/aasthajs Newsletter: https://livelongerworld.com/
Instagram: https://www.instagram.com/aasthajs/ Michael Levin: https://twitter.com/drmichaellevin Mustafa's publications: https://profiles.imperial.ac.uk/m.djamgoz/publications Mustafa's book Beat Cancer: https://www.amazon.com/Beat-Cancer-Regain-Control-Health-ebook/dp/B00CU8QBAS Episode Show Notes: https://livelongerworld.com/p/djamgoz Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8?si=WrQ_iI8ABbG6eibm
Genes are NOT the "blueprint of life" | Dr. Alfonso Martinez Arias
Dr. Alfonso Martinez Arias is a development biologist and the author of the book The Master Builder: How the New Science of the Cell Is Rewriting the Story of Life. He also co-authored the biology textbook …
Show notes
Dr. Alfonso Martinez Arias is a development biologist and the author of the book The Master Builder: How the New Science of the Cell Is Rewriting the Story of Life. He also co-authored the biology textbook Principles of Development, which was awarded the Royal Society of Biology book prize. Episode Show Notes: https://livelongerworld.com/p/aarias OVERVIEW: Each of our cells has the same DNA. Yet they somehow differentiate into different body parts - eyes, ears, skin, and so on. There is no information in the DNA that tells our cells what to be. How then do they do it? This is just one example of how contrary to what many might think, DNA does not explain every problem state in biology. Biology has placed too much emphasis on our genes, trying to explain every disease state using genes, when the answer might not reside with them. What if answers to these questions lies with cells? Even though Dr. Martinez started off as a geneticist, he decided to pivot to understand the properties of cells better. By understanding our cells better, we can make further progress in understanding disease, longevity, and development.
Towards the end, we also talk about Alfonso's fascinating work on gastruloids which are a model to unravel the mysteries of embryonic development, and understand how humans are formed. This conversation is about the cell’s eye view of biology, and how the gene's eye view of biology might have mislead us. We also talk about why the popular selfish gene theory espoused by Richard Dawkins is incomplete. Looking beyond genes is instrumental to making progress in longevity.
Episode Show Notes: https://livelongerworld.com/p/aarias Find me: https://x.com/aasthajs TIMESTAMPS: 0:00 Intro 1:15 DNA does not make us unique 5:28 Cells use our genes 10:42 “We have overstretched what genes can explain” 15:41 Relation between genes and cells 20:28 What about the role of epigenetics? 22:42 Cells use mechanical and chemical signals 27:34 Thoughts on bioelectricity and Michael Levin 32:28 Emergence of cells 38:10 Importance of biophysics; What is life? 42:32 Is cancer when cells lose control? 47:58 Richard Dawkins’ Selfish Gene is Incomplete 54:11 But what if genes control development? 57:29 How to complete the selfish gene view? 1:02:05 Cell’s eye view of biology 1:04:48 Understanding embryonic development; gastruloids 1:18:15 Questions Dr. Alfonso is pursuing1:19:47 Thoughts from Feynman AASTHA, LIVE LONGER WORLD: X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ DR. ALFONSO MARTINEZ ARIAS: Master Builder book: https://www.amazon.com/Master-Builder-Science-Rewriting-Story/dp/1541603273 X: https://x.com/AMartinezArias Bio page: https://www.icrea.cat/Web/ScientificStaff/alfonso-martinez-arias-352001
The Evolutionary Theory of Cancer | Dr. Charley Lineweaver
The following is a fascinating interview with Dr. Charley Lineweaver, who worked with Paul Davies on his work on cancer which we discuss. Episode Show Notes: https://livelongerworld.com/p/clineweaver Topics …
Show notes
The following is a fascinating interview with Dr. Charley Lineweaver, who worked with Paul Davies on his work on cancer which we discuss. Episode Show Notes: https://livelongerworld.com/p/clineweaver Topics include: - the evolutionary and atavistic theory of cancer - the incorrectness of the somatic mutation theory of cancer - a novel take on attacking the weakness of cancer - how embryogenesis could be viewed as cells reverting to old memory - the origins of multicellularity - “Cancer cannot do anything new” The atavistic theory of cancer states that cancer cells revert to an old memory they have from billions of years, but forget the new memory. The old memory pertains to constant cell proliferation, which happened as single-celled creatures, and in fact in embryogenesis as well. The new memory pertains to regulating cell proliferation and cells knowing when to stop cellular division. In cancer, it seems like cells forget this new memory and revert to the old memory. This theory has many interesting explanations and predictions which we dive into in the conversation. Enjoy! Episode Show Notes: https://livelongerworld.com/p/clineweaver Find me: https://x.com/aasthajs TIMESTAMPS: 0:00 Background in astrobiology 1:53 Evolutionary theory of cancer 6:22 Atavistic model: Cancer cells go back to “original state” 9:50 Atavistic theory vs. Cancer 14:44 Somatic Mutation Theory of Cancer is Wrong 22:36 Disagreement with Mike Levin’s work 24:17 Attack the weakness of cancer 27:45 Vaccine for cancer 38:08 Wound healing and cancer 41:23 Why new genes are more susceptible to damage 45:26 Origins of multicellularity 48:49 Predictions of Atavistic model 53:45 Cancer cells spread 56:52 Cell proliferation, Cancer, Hayflick limit 58:54 Doctors are not trained in evolution AASTHA, LIVE LONGER WORLD: Twitter: https://x.com/aasthajs Newsletter: https://livelongerworld.com/
Instagram: https://www.instagram.com/aasthajs/ DR. CHARLEY LINEWEAVER: Website: https://researchers.anu.edu.au/researchers/lineweaver-ch Papers referenced: - Cancer progression as a series of atavistic reversions: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860064/
- Targeting cancer's weaknesses, not its strengths: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282648/
Michael Levin & Ken Robinson | Bioelectricity in the era of the Genetic Code
This is the third in my series with Dr. Michael Levin where we interview significant people in the history of developmental bioelectricity. Ken Robinson has a long list of accomplishments in the bioelectricity …
Show notes
This is the third in my series with Dr. Michael Levin where we interview significant people in the history of developmental bioelectricity. Ken Robinson has a long list of accomplishments in the bioelectricity field, covering the role of electric fields in guiding cell migration and more generally the function of electrogenic epithelia in embryogenesis. This is about a ~1 hour conversation in which he talks about his background, the history of the field, and his time in Lionel Jaffe's lab. Episode Show Notes: https://livelongerworld.com/p/krobinson Find me: https://x.com/aasthajs Background on the bioelectricity series & 1st episode with Dr. Richard Nuccitelli: https://www.livelongerworld.com/p/rnuccitelli TIMESTAMPS: 0:00 Intro
0:38 Ken’s background - From physics to bioelectricity
6:10 Bioelectricity in the era of the “genetic code”
10:27 Ken’s first experiments in ion movement using light
23:25 Proton pump and its significance
26:07 Neurons respond to electrical signals
36:26 Working in Lionel Jaffe’s lab
47:39 Mike Levin as an undergrad
48:49 Membrane potential left-right asymmetry in cells
52:59 Epithelia is powerfully electrogenic
57:49 Advances for bioelectricity
59:27 Underrated people in the field AASTHA, LIVE LONGER WORLD: Twitter: https://x.com/aasthajs Newsletter: https://livelongerworld.com/ Michael Levin: https://twitter.com/drmichaellevin Mike's bibliography of bioelectricity: https://thoughtforms.life/my-reference-lists-whole-endnote-library-and-bibliography-on-bioelectromagnetics/ Episode Show Notes: https://livelongerworld.com/p/krobinson Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8?si=WrQ_iI8ABbG6eibm
Michael Levin & Min Zhao | Bioelectricity in Wound Repair
This is the second of several interviews Michael Levin and I will do with significant people in the history of developmental bioelectricity. Min Zhao's work is focused on the role of ion currents and applied …
Show notes
This is the second of several interviews Michael Levin and I will do with significant people in the history of developmental bioelectricity. Min Zhao's work is focused on the role of ion currents and applied electric fields in cell migration and wound repair. Episode Show Notes: https://livelongerworld.com/p/mzhao Find me: https://x.com/aasthajs Background on the bioelectricity series & 1st episode with Dr. Richard Nuccitelli: https://youtu.be/DtUqOwTRvz0?si=3OJryM0yJjzfQtfo TIMESTAMPS: 0:00 Min’s background from trauma surgery to bioelectricity 5:14 Bioelectricity in wound healing 13:51 Potential and challenges of bioelectricity in wound healing 21:40 Min’s take on Robert Becker’s work 24:53 Scientists in the field Min drew got inspired by 29:36 The era before Lionel Jaffe 32:39 Experiments in wound healing using bioelectricity 45:43 Min’s current explorations AASTHA, LIVE LONGER WORLD: Twitter: https://x.com/aasthajs Newsletter: https://livelongerworld.com/ Michael Levin: https://twitter.com/drmichaellevin Min Zhao: https://health.ucdavis.edu/dermatology/faculty/zhao.html Episode Show Notes: https://livelongerworld.com/p/mzhao Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8?si=WrQ_iI8ABbG6eibm
Glyphosate Toxicity & Deuterium's Role in Cancer, Celiac, Aging | Dr. Stephanie Seneff
Stephanie Seneff is the pioneer in raising concerns around glyphosate, a chemical and active ingredient in RoundUp and other pesticides, which has practically infiltrated our food system, water bodies, and …
Show notes
Stephanie Seneff is the pioneer in raising concerns around glyphosate, a chemical and active ingredient in RoundUp and other pesticides, which has practically infiltrated our food system, water bodies, and soil. Glyphosate has been linked to several diseases including liver disease, autoimmunity, neurological disorders, reproductive issues, microbiome problems, and more. Dr. Stephanie Seneff has spent 10+ years researching glyphosate’s harmful impact on our health, and documented her findings in her book Toxic Legacy: How the Weedkiller Glyphosate is Destroying our Health and the Environment. More recently, Stephanie has been doing research on deuterium (a hydrogen isotope in the body) and how glyphosate can cause an excess of deuterium, potentially leading to cancer and other health consequences. Glyphosate is affecting each one of us. It’s worth paying attention to this toxic chemical. Episode Show Notes: https://livelongerworld.com/p/sseneff Find me (Aastha) on X: https://x.com/aasthajs DR. STEPHANIE SENEFF LINKS: Website: https://stephanieseneff.net/ X: https://x.com/stephanieseneff Book: https://www.amazon.com/Toxic-Legacy-Stephanie-Seneff/dp/1603589295/ AASTHA, LIVE LONGER WORLD: X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ Airchat: https://www.getairchat.com/aasthajs TIMESTAMPS: 0:00 Autism in children, vaccines, glyphosate 2:30 Aluminum and fluoride in water 3:47 Glyphosate in our food and its toxicity 6:05 Celiac’s link to glyphosate 8:25 Glyphosate impacting collagen in our bodies 12:55 Soil regeneration after glyphosate 15:24 Breaking down glyphosate in our waterways 16:36 Glyphosate causing sulfate deficiency; cruciferous veggies 18:43 Sulfate powers bioelectricity in our cells; Gerald Pollack 21:23 Avoid sunscreen? 22:25 Deuterium and its toxicity 25:20 How Stephanie started looking at Deuterium 26:36 Low deuterium water good for health? 29:25 Excess deuterium causing cancer 30:52 Stephanie’s wild theory on curing cancer 35:19 What else causes increase in deuterium 35:38 Glyphosate in rain water 36:25 PSCSK9 inhibitors harmful with glyphosate 38:49 Solutions to avoid glyphosate 42:23 U.S. stopped Mexico banning glyphosate Episode Show Notes: https://livelongerworld.com/p/sseneff
Michael Levin & Richard Nuccitelli | History of Bioelectricity & Solving Cancer
This is the first of several interviews Michael Levin and I will do with significant people in the history of developmental bioelectricity. Richard Nuccitelli is a legend, having invented (with Lionel Jaffe, in …
Show notes
This is the first of several interviews Michael Levin and I will do with significant people in the history of developmental bioelectricity.
Richard Nuccitelli is a legend, having invented (with Lionel Jaffe, in 1974) the Vibrating Probe - a technique that allowed the non-invasive sensing of ion currents around living tissues. This is about a ~1 hour conversation in which he talks about his background, the history of the field, and his current clinical work on the bioelectrics of cancer. Episode Show Notes: https://livelongerworld.com/p/rnuccitelli
Find me: https://twitter.com/aasthajs BACKGROUND: In 2022, I interviewed Dr. Michael Levin on his work on bioelectricity in cells and how that has the potential to solve cancer and aging. Since then, Mike has also appeared on Lex Fridman and many other podcasts talking about his revolutionary work. Amongst all the podcasts I did, Mike’s work struck me as profound yet underappreciated. The field of biology has focused on the DNA and the relevance of the electric currents in our cells is not appreciated. Yes, the electrical energy powering our cells is what keeps us alive! Earlier this year, I decided to dive deeper into bioelectricity. I’m starting by exploring the history of the field in conjunction with Michael Levin. We’re doing a series of interviews talking to scientists in the field to understand the origins of the field, bottlenecks, progress so far, and what the future could look like. Today's interview is the first in the series with Dr. Richard Nuccitelli. TIMESTAMPS: 0:00 Intro to History of Bioelectricity Series 1:09 How Rich got interested in bioelectricity 4:34 Bioelectrics didn't make it to biology literature 7:55 Vibrating probe use cases 10:20 Bioelectrics in 1970s 13:37 Why is bioelectrics underrated? 22:50 Field progression 29:02 Ultra high voltage in treating cancer 39:00 Understanding significance of bioelectrics from 1900s 44:40 Working with Lionel Jaffe 50:27 How Mike entered bioelectrics 54:02 Criticism received by bioelectrics? 57:04 Missing technology to advance bioelectrics 1:00:52 Electrical patterns in cells with age 1:03:12 Image of electrics in organisms AASTHA, LIVE LONGER WORLD: Twitter: https://twitter.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ Airchat: https://www.getairchat.com/aasthajs Michael Levin: https://twitter.com/drmichaellevin Richard Nuccitelli: https://www.linkedin.com/in/nuccitelli/ Episode Show Notes: https://livelongerworld.com/p/rnuccitelli
Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8?si=WrQ_iI8ABbG6eibm
FDA History and Breast Cancer Drug Controversy | Dr. Mikkael Sekeres
Dr. Mikkael Sekeres is the author of the book The Drugs and FDA. He served as the chair of the Oncology Drugs Advisory Committee of the FDA, and was on the jury for the controversial trial of the breast cancer …
Show notes
Dr. Mikkael Sekeres is the author of the book The Drugs and FDA. He served as the chair of the Oncology Drugs Advisory Committee of the FDA, and was on the jury for the controversial trial of the breast cancer drug Avastin. We discuss: - The history of the FDA, - The trial of Avastin which got FDA approval in 2008 and revoked in 2011 - FDA's funding mechanisms - FDA ties to big pharma - What can be improved about the FDA and the criticisms it receives
Episode Show Notes: https://livelongerworld.com/p/msekeres TIMESTAMPS: 0:00 Surprising finding about the FDA 2:38 Why did the FDA get established in 1938? 11:48 1962 turning point in the FDA & Thalidomide 19:57 Kennedy’s efficacy act on drugs approval 25:40 FDA’s accelerated approval; HIV & AIDS 33:23 Avastin breast cancer drug controversy 41:13 Why was Avastin trial contentious? 45:23 Genentech’s argument 50:00 Media reaction 53:21 FDA funded by big pharma 56:39 FDA vs. patient activist groups 59:50 Opioid crisis 1:03:30 Does the FDA go against advisory committee? CONNECT WITH AASTHA, LIVE LONGER WORLD: Twitter: https://twitter.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ Airchat: https://www.getairchat.com/aasthajs DR. MIKKAEL SEKERES LINKS: Website: https://www.mikkaelsekeres.com/ Twitter: https://twitter.com/MikkaelSekeres
Book: https://www.amazon.com/Drugs-FDA-Safety-Efficacy-Publics/dp/0262047314 If you enjoyed the episode, please share it and leave a rating. Best, Aastha.
#27 Women's Reproductive Aging, Menopause, & Hormone Replacement Therapy | Dr. Jennifer Garrison
Dr. Jennifer Garrison is a an Assistant professor at the Buck Institute for research on aging where she studies women's reproductive aging. In today’s conversation we discussed menopause and it’s effect on …
Show notes
Dr. Jennifer Garrison is a an Assistant professor at the Buck Institute for research on aging where she studies women's reproductive aging. In today’s conversation we discussed menopause and it’s effect on women’s health, hormone replacement therapy, and how increasing the number of quality eggs a woman has at age 40 by just 1% can be a game changer.
Episode Show Notes: https://livelongerworld.com/p/jgarrison
Find the previous podcast episodes & subscribe to be notified: https://livelongerworld.com/ Find me (Aastha) on Twitter: https://twitter.com/aasthajs
DR. JENNIFER GARRISON LINKS: Lab: http://garrisonlab.com/ Donate to her research: https://gcrle.org/ CONNECT WITH AASTHA, LIVE LONGER WORLD: Twitter: https://twitter.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ Airchat: https://www.getairchat.com/aasthajs
TIMESTAMPS: 00:00 Intro 1:38 Jennifer Garrison Intro 2:32 Ovarian aging & health risks 5:23 Progression of Ovarian aging 8:49 Menopause and negative health effects 10:34 Hypothalamus & Mind body communication 14:40 Reproductive & Equality Initiatives 18:21 Biological Clock for Reproductive aging 20:20 Tweaking hormonal cues 22:07 Number of eggs vs. Quality of eggs 25:00 Genetics in ovarian aging 26:21 Understanding family history 27:39 Evolutionary benefit to Menopause? 32:33 Hormone Replacement Therapy (HRT) & its benefits 38:28 Narrow window for HRT 40:08 Perimenopause 42:56 Women’s health funding 45:14 Average age girls start menstruating is declining 49:10 PCOS 52:42 Athletes and irregular cycles 56:36 Individualized menopause symptoms 1:00:38 Exercise and ovarian aging 1:02:00 Support Jennifer's work
Episode Show Notes: https://livelongerworld.com/p/jgarrison POPULAR EPSIODES: - Richard Miller on Longevity Supplements: https://youtu.be/42PzfNs9egA - Matt Kaeberlein on Rapamycin: https://youtu.be/BL67DhNepfg - Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8 - Nir Barzilai on Metformin & Centenarians: https://youtu.be/YlkBE8N7sl8 - Morgan Levine on Epigenetic Clocks: https://youtu.be/am3YKiTpCHo
Thanks for watching & if you enjoy the episode, let's spread the message on longevity. You can support my work by sharing, liking, subscribing, leaving a review on Apple podcasts, or signing up as a premium member.
Aging is universal. Let's unite in this fight. Stay in good health - Aastha.
#26 Scaling Laws in Longevity & Aging | Dr. Geoffrey West, Author of book Scale
Dr. Geoffrey West is the author of the bestselling book Scale, the Universal Laws of Life Growth and Death in Organisms, cities and Companies. He is a physicist who got fascinated by the field of aging and …
Show notes
Dr. Geoffrey West is the author of the bestselling book Scale, the Universal Laws of Life Growth and Death in Organisms, cities and Companies. He is a physicist who got fascinated by the field of aging and longevity and asked the question of why we live as long as we do and no longer. In today's episode, we dive into his research on the scaling laws in biology and longevity.
Episode Show Notes: https://livelongerworld.substack.com/p/gwest Find the previous podcast episodes & subscribe to be notified: https://livelongerworld.substack.com/
Find me (Aastha) on Twitter: https://twitter.com/aasthajs
DR. GEOFFREY WEST LINKS: Profile: https://www.santafe.edu/people/profile/geoffrey-west Book: https://amzn.to/3Xtl7wU CONNECT WITH AASTHA, LIVE LONGER WORLD:
Newsletter: https://livelongerworld.substack.com/
Twitter: https://twitter.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
Airchat: https://www.getairchat.com/aasthajs
TIMESTAMPS: 1:35 Context on Dr. West's book Scale 9:00 Networks in biology & cities 22:50 Scaling laws in longevity
32:33 Upper limit to human age?
39:08 Quantifying Caloric restriction
41:52 Metabolism & Body temperature
49:05 Scaling laws in age-related damage
56:35 Scaling body sizes across species
1:01:38 Scaling laws in drug dosage (LSD & Elephants)
1:11:06 Drug dosage in children (Tylenol & babies)
1:13:44 Vaccine dosage scaling laws
1:17:51 Sleep & Aging in different organisms
1:31:22 Early stimulation for child development
1:36:35 Fasting, meal frequency & digestive time
1:39:10 Sleep demands with work & physical activity
1:43:40: Scaling laws in cities, companies & universities
2:02:00 Outro
POPULAR EPSIODES:
Richard Miller on Longevity Supplements: https://youtu.be/42PzfNs9egA
Matt Kaeberlein on Rapamycin: https://youtu.be/BL67DhNepfg
Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8
Nir Barzilai on Metformin & Centenarians: https://youtu.be/YlkBE8N7sl8
Morgan Levine on Epigenetic Clocks: https://youtu.be/am3YKiTpCHo
Thanks for watching & if you enjoy the episode, let's spread the message on longevity. You can support my work by sharing, liking, subscribing, leaving a review on Apple podcasts, or signing up as a premium member. Aging is universal. Let's unite in this fight. Stay in good health - Aastha.
#25 Caloric Restriction Deep-Dive & Longevity Secrets of Long-Lived Animals | Dr. Steven Austad
All platforms / Episode Transcript: https://livelongerworld.substack.com/p/saustad Dr. Steven Austad is a professor in the Healthy Aging department at the University of Alabama and also scientific director of …
Show notes
All platforms / Episode Transcript: https://livelongerworld.substack.com/p/saustad
Dr. Steven Austad is a professor in the Healthy Aging department at the University of Alabama and also scientific director of the American Federation for Aging research. He has a fascinating entry into the world of aging research - it all began with training lions!
There are many open questions on the caloric restriction research for enhancing longevity and we dive into that. Further, a lot of Dr. Austad’s work focuses on what long-lived animal species can teach us about living longer and healthier lives. His lab works on exotic species, like clams that live more than 500 years, and hydra that don’t age at all, in order to discover aging treatments. He also tries to uncover the mysteries around why men and women respond differently to longevity therapeutics.
Find the previous podcast episodes & subscribe to be notified: https://livelongerworld.substack.com/
Find me (Aastha) on Twitter: https://twitter.com/aasthajz
DR. STEVEN AUSTAD LINKS:
Website: https://www.stevenaustad.com/
Twitter: https://twitter.com/StevenAustad
Faculty page: https://www.uab.edu/cas/biology/people/faculty/steven-n-austad
CONNECT WITH AASTHA, LIVE LONGER WORLD:
Website: https://www.livelongerworld.com/
Twitter: https://twitter.com/aasthajz
Newsletter: https://livelongerworld.substack.com/
Instagram: https://www.instagram.com/aasthajz/
TIMESTAMPS:
0:00 Training lions
7:15 Learning from Long-lived species
9:55 Bowhead whales live 200 years
12:55 House sparrows & longevity
14:40 Study "successful" animals
18:10 Naked Mole Rats
20:45 What do bowhead whales die from?
26:05 Why do ocean animals live longest?
31:05 Beyond Caloric Restriction
36:00 Intermittent Fasting & Circadian Rhythm
42:40 Caloric Restriction for Healthy people?
46:24 Will coffee shorten your life?
49:43 The Blue Zone Myth
55:50 Young Blood, I can't get you of out my Mind
1:00:26 Hormones & Health (Growth Hormones for longevity?)
1:05:18 Sex differences in longevity
Episode Show Notes: https://livelongerworld.substack.com/p/saustad
POPULAR EPSIODES:
- Richard Miller on Longevity Supplements: https://youtu.be/42PzfNs9egA
- Matt Kaeberlein on Rapamycin: https://youtu.be/BL67DhNepfg
- Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8
- Nir Barzilai on Metformin & Centenarians: https://youtu.be/YlkBE8N7sl8
- Morgan Levine on Epigenetic Clocks: https://youtu.be/am3YKiTpCHo
Thanks for watching & if you enjoy the episode, let's spread the message on longevity.
You can support my work by sharing, subscribing, leaving a review on Apple podcasts, donating on Patreon, or signing up as a premium member. Aging is universal. Let's unite in this fight. Stay in good health - Aastha.
#24 Dr. Dominic D'Agostino | Modified Ketogenic Diet for Optimal Health & Exercise (Part 2)
All platforms / Episode Transcript & Timestamps: https://livelongerworld.substack.com/p/dom2 Dr. Dom D’Agostino may require no introduction especially in the world of ketosis! He is an Associate Professor with …
Show notes
All platforms / Episode Transcript & Timestamps: https://livelongerworld.substack.com/p/dom2
Dr. Dom D’Agostino may require no introduction especially in the world of ketosis! He is an Associate Professor with his research focusing on metabolic therapies, ketogenic diets, ketone supplements, and other metabolic based drugs. He is also a research scientist at the Institute of Human and Machine Cognition.
This is Part 2 of a 2 part conversation with Dom. He has so much knowledge to share and in this episode we dive into the ketogenic diet for exercise performance, keto for women & children, Dom's diet & supplement routine + more! Hope you enjoy the episode!
Part 1 with Dom on Ketogenic diets for Brain Health and Longevity: https://livelongerworld.substack.com/p/dom1
Find the previous podcast episodes & subscribe to be notified: https://livelongerworld.substack.com/
Find me (Aastha) on Twitter: https://twitter.com/aasthajz
SUPPORT LIVE LONGER WORLD:
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DOM D'AGOSTINO LINKS:
KetoNutrition: https://ketonutrition.org/
Website: https://linktr.ee/Domdagostino
Twitter: https://twitter.com/DominicDAgosti2
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TIMESTAMPS:
0:00 Ketogenic diet for muscle performance
0:50 Dom’s supplements & modified keto diet
3:20 Keto, NAD+, NMN 7:12 Biomarkers tracked by Dom
9:30 LDL, Triglycerides, Fatty Foods & Keto diet
14:15 Dom’s routine & supplements
18:09 Melatonin benefits for anti-cancer & antioxidant
22:37 Ketogenic diet for women
30:55 Ketogenic diet for children
32:48 Genetic aspect to keto diet?
38:32 Metformin for suppressing cancer
46:30 Ketogenic diet & Alzheimer’s
54:40 Exercise for mental health
55:53 Keto for exercise performance & bodybuilding
59:32 Endogenous metabolite & psychedelics
1:09:05 Connect with me (Aastha)
Episode Show Notes: https://livelongerworld.substack.com/p/dom2
Thanks for watching & if you enjoy the episode, let's spread the message on longevity. If you like the podcast, please leave a review on Apple podcasts.
Aging is universal. Let's unite in this fight. Stay in good health - Aastha.
#23 Dominic D'Agostino | Ketogenic Diet for Brain Health and Longevity (Part 1)
All platforms / Episode Transcript & Timestamps: https://livelongerworld.substack.com/p/dom1 Dr. Dom D’Agostino may require no introduction especially in the world of ketosis! He is an Associate Professor with …
Show notes
All platforms / Episode Transcript & Timestamps: https://livelongerworld.substack.com/p/dom1
Dr. Dom D’Agostino may require no introduction especially in the world of ketosis! He is an Associate Professor with his research focusing on metabolic therapies, ketogenic diets, ketone supplements, and other metabolic based drugs. He is also a research scientist at the Institute of Human and Machine Cognition.
This is Part 1 of a 2 part conversation with Dom. He has so much knowledge to share and in this episode we dive into the history of ketogenic diets, keto for brain health and neuroprotective seizures, keto for longevity benefits, weight training, caloric restriction and more. Hope you enjoy the episode!
Find the previous podcast episodes & subscribe to be notified: https://livelongerworld.substack.com/
Find me (Aastha) on Twitter: https://twitter.com/livelongerworld
SUPPORT LIVE LONGER WORLD:
Sign up for Premium Subscriber Transcripts: https://www.livelongerworld.com/premium
Patreon: https://www.patreon.com/livelongerworld
One-Time support: https://www.paypal.com/paypalme/livelongerworld
DOM D'AGOSTINO LINKS:
KetoNutrition: https://ketonutrition.org/
Website: https://linktr.ee/Domdagostino
Twitter: https://twitter.com/DominicDAgosti2
CONNECT WITH AASTHA, LIVE LONGER WORLD:
Website: https://www.livelongerworld.com/
Twitter: https://twitter.com/livelongerworld
Newsletter: https://livelongerworld.substack.com/
Instagram: https://www.instagram.com/longevityfuture/
TIMESTAMPS:
0:00 Ketogenic diet is not optimal for everyone
0:56 Dom D’Agostino Intro
1:29 Plant-based ketogenic diet
3:20 Ketogenic diet & brain protection against seizures
16:40 Ketone Esters & Salts
19:29 Does the brain need glucose?
21:37 Intermittent Ketosis & Fasting Mimicking Diet
25:17 Cyclic Ketogenic diet for longevity
28:40 Devices for tracking ketosis
30:30 Ketogenic diet for longevity vs. Caloric restriction
37:50 Keto diet for cancer prevention
41:57 Keto diet, Insulin pathway, and glucose
46:50 Time restricted eating benefits
50:17 Dom vs. Layne Norton on Joe Rogan podcast
51:40 Muscle for longevity (especially for women)
56:10 Support Live Longer World
Episode Show Notes: https://livelongerworld.substack.com/p/dom1
Thanks for watching & if you enjoy the episode, let's spread the message on longevity.
You can support my work by sharing, liking, subscribing, leaving a review on Apple podcasts, donating on Patreon, or signing up as a premium member.
Aging is universal. Let's unite in this fight. Stay in good health - Aastha.
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