Can Biological Age Clocks Show Which Longevity Strategies Work?
Show notes
Guest:
Christin Glorioso, MD. Ph.D.
Creator of the Younger Biological Aging Contest, Founder & CEO of NeuroAge Therapeutics
LinkedIn: https://www.linkedin.com/in/christin-glorioso-md-phd-39627719/
Website: https://www.neuroagetx.com/authors/christin-glorioso
Ryan Smith
Co-Founder and Director of Research & Development at TruDiagnostic
LinkedIn: https://www.linkedin.com/in/ryan-smith-lexington-ky/
Website: https://www.trudiagnostic.com/
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What if measuring biological age could show which interventions actually improve health?
Phil Newman sits down with Dr. Christin Glorioso, physician, neuroscientist and founder of NeuroAge and Longevity Global, and Ryan Smith of True Diagnostic to explore the Younger biological aging contest and the future of aging biomarkers.
They explain how its six-month challenge combines DNA methylation, proteomics, RNA and glycan clocks with brain imaging and physical-function tests. The resulting data could help compare biomarkers, personalize interventions and strengthen evidence for clinical trials.
They also discuss brain health, GLP-1 research, surrogate endpoints and how AI could accelerate biomarker validation.
In this episode, you'll learn:
- What Younger measures
- How multi-omics can refine biological age testing
- Which lifestyle factors show promising signals
- How brain data can guide personalized recommendations
- What biomarkers need before regulators can rely on them
This episode connects emerging aging science with practical routes toward personalized, preventative healthcare.
Subscribe for weekly episodes on longevity science, preventative medicine and healthier, longer lives.
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Host:
Phil Newman: https://qrco.de/bgXpNY