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Urinary Tract Infection (UTI)

July 16, 2026 · 32 min

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Ninja Nerds!

In this episode of the Ninja Nerd Podcast, Zach and Rob walk you through a high-yield, case-based approach to urinary tract infections, focusing on how to differentiate simple from complicated disease and make the right management decisions quickly. This is a core topic you will see everywhere, from outpatient clinics to emergency settings to board exams.

We start with a classic lower urinary tract case and build a framework for recognizing cystitis, including key symptoms and risk factors. From there, we break down the diagnostic approach, including when urinalysis is enough, when to send cultures, and how to interpret findings in a clinically meaningful way.

Next, we escalate to upper tract disease, focusing on pyelonephritis and the red flags that signal more serious infection. You will learn how to identify systemic involvement, when imaging is necessary, and how to adjust management based on severity.

Finally, we cover treatment strategies, including first-line antibiotics, the duration of therapy, and approaches to recurrent and complicated infections.

Let’s get into it, Ninja Nerds!

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