Skip to content

#567: Personal AI Agents for Pythonistas

October 27, 2026 · 1 h 7 min

Show notes

The most popular Python project you've probably never heard of has 252,000 GitHub stars and merged over 1,800 pull requests in a single week. It's Hermes, a self-hosted AI agent you program just by talking to it. And it never clocks out. It runs 24/7 on a box in your house, wakes up every 15 minutes, keeps your YouTube channel in sync, and has your morning briefing ready before you're up. Mine started as a few config files. A few months later, it's 16,000 files of skills, memories, and tools it built for itself, all while I wasn't watching. Jeff Triplett joins me to explore this honestly weird but kind of amazing world. And yes, Hermes has a few words for you, too.

Episode sponsors

Talk Python Membership
Talk Python Membership
Talk Python Courses

Links from the show Talk Python Tech Talks: talkpython.fm/meetups

Hermes: github.com
Ollama cloud models: ollama.com
https\://hermes-agent.nousresearch.com: hermes-agent.nousresearch.com
Hermes Web UI: get-hermes.ai
built my own UI: blobs.talkpython.fm
the Hermes Dashboard: blobs.talkpython.fm
the audio from the chat example: blobs.talkpython.fm
the CLI: blobs.talkpython.fm
Tailscale: tailscale.com
Hindsight: hindsight.vectorize.io
trmnl display: trmnl.com
JEV: typesafe.ai
Home Assistant Green: www.home-assistant.io
QMD - Query Markup Documents: github.com
OrangePi: www.orangepi.org

Watch this episode on YouTube: youtube.com
Episode #567 deep-dive: talkpython.fm/567
Episode transcripts: talkpython.fm

Theme Song: Developer Rap
🥁 Served in a Flask 🎸: talkpython.fm/flasksong

---== Don't be a stranger ==---
YouTube: youtube.com/@talkpython

Bluesky: @talkpython.fm
Mastodon: @[email protected]
X.com: @talkpython

Michael on Bluesky: @mkennedy.codes
Michael on Mastodon: @[email protected]
Michael on X.com: @mkennedy

All episodes of Talk Python To Me

Settings

Display

Language

Decides which stations you see first on the home page.

History

Recently played stations and episodes and your latest searches are only stored in this browser.

Notifications

A short notice when a podcast you follow has a new episode. Turn off single podcasts with the bell on their page.

Account

Save favorites – in the app and on the website.

Keyboard shortcuts

/
Open search
Space
Play or pause
← →
In the player: back 15 s, forward 30 s (episodes) · in a row: next tile
↑ ↓
In a row: target within the tile
Home / End
In a row: first or last tile
Esc
Close window or menu
?
This overview
Now playing

Go to station page

Play next

    Add episodes with “Play next” – they play after the current episode.