Skip to content

#568: Cloudflare Python Workers

November 3, 2026 · 1 h 2 min

Show notes

Where does your Python code actually run? A server in Virginia? A container in Frankfurt? Pyodide put Python into the browser. Cloudflare put the browser into the server. Combine the two and you get Python Workers, now generally available. My guests are Hood Chatham, Gyeongjae Choi, and Dominik Picheta from Cloudflare. Hood and Gyeongjae maintain Pyodide. Dominik got Python running in Cloudflare Workers in the first place. Your FastAPI app ships as plain Python files. It runs on CPython compiled to WebAssembly, inside V8, at over 350 locations worldwide.

Episode sponsors

Talk Python Membership
Talk Python Membership
Talk Python Courses

Links from the show Guests
Gyeongjae Choi: linkedin.com
Hood Chatham
Dominik Picheta

Pyodide: pyodide.com
Python Everywhere: The State of Python on WebAssembly - Hood Chatham, Gyeongjae Choi: www.youtube.com
PEP 783: peps.python.org
D1 Databases: www.cloudflare.com
Hyperdrive: www.cloudflare.com
R2 Object Storage: www.cloudflare.com
Queues: developers.cloudflare.com
AI: www.cloudflare.com
now generally available: blog.cloudflare.com
Memory Snapshots for CPython (Python Language Summit 2026\): blog.python.org
Cloudflare Worker Limits: developers.cloudflare.com
Litestream: litestream.io
workerd: github.com
Are we PEP 783 yet?: pyodide.github.io
The Birth & Death of JavaScript: www.destroyallsoftware.com

Watch this episode on YouTube: youtube.com
Episode #568 deep-dive: talkpython.fm/568
Episode transcripts: talkpython.fm

Theme Song: Developer Rap
🥁 Served in a Flask 🎸: talkpython.fm/flasksong

---== Don't be a stranger ==---
YouTube: youtube.com/@talkpython

Bluesky: @talkpython.fm
Mastodon: @[email protected]
X.com: @talkpython

Michael on Bluesky: @mkennedy.codes
Michael on Mastodon: @[email protected]
Michael on X.com: @mkennedy

All episodes of Talk Python To Me

Settings

Display

Language

Decides which stations you see first on the home page.

History

Recently played stations and episodes and your latest searches are only stored in this browser.

Notifications

A short notice when a podcast you follow has a new episode. Turn off single podcasts with the bell on their page.

Account

Save favorites – in the app and on the website.

Keyboard shortcuts

/
Open search
Space
Play or pause
← →
In the player: back 15 s, forward 30 s (episodes) · in a row: next tile
↑ ↓
In a row: target within the tile
Home / End
In a row: first or last tile
Esc
Close window or menu
?
This overview
Now playing

Go to station page

Play next

    Add episodes with “Play next” – they play after the current episode.