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Are Compounded GLP-1s Safe?

November 11, 2026 · 35 min

Show notes

What's actually in a compounded GLP-1?
What is compounding?
How can you tell if that ad on Instagram is legit?
Why are poison control centers getting more calls about these drugs?
What should you do if you are on one right now?

We tackle ALL those questions on this week's episode of the pod.

We thank ASEM for sponsoring today's episode.

You can also watch the convo on YouTube: https://youtu.be/8fe5nGbeSSg

(00:00) Intro
(03:15) What is compounding?
(09:50) What exactly is IN compounded GLP-1s?
(14:30) What are "Research Use Only" products such as "reta?"
(17:37) What are red flags to watch out for on social media ads?
(19:45) What does FDA approval require for a drug to make it to market?
(22:10) Why do some clinicians not prescribe compounded GLP-1s?
(26:46) What about people turning to compounded GLP-1s due to cost?
(30:00) What if you are already on one of these compounds?
(31:35) Final Thoughts and Key Takeaways

https://medcitynews.com/author/fmills/
https://safeandeffectivemeds.org
https://www.endocrineclinicatthegym.com/
https://www.mskcc.org/profile/leigh-baxt
https://www.fda.gov/media/185577/download
https://www.goodrx.com/classes/glp-1-agonists/semaglutide-shortage
https://safeandeffectivemeds.org/wp-content/uploads/2026/07/ASEM_Survey-Readout.pdf
https://www.beckershospitalreview.com/glp-1s/fda-warns-on-compounded-glp-1s-amid-1700-safety-reports/
https://www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss
https://jamanetwork.com/journals/jama-health-forum/fullarticle/2851339?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=071726#google_vignette
https://poisoncenters.org/track/GLP-1
https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program


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