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51 Insights – What’s next in digital assets, AI and markets.
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51 Insights – What’s next in digital assets, AI and markets.

NouveauIllia Polosukhin: "Not Your AI, Not Your Intelligence"12 novembre 2026 · 57 min
Épisodes
68
Parution
hebdomadaire
Dernier épisode
12 Nov 2026

À propos du podcast

We talk with digital asset, AI and technology leaders about what's next in finance and commerce. Subscribe to our newsletter & join 35k+ others: https://join.fiftyone.xyz/

Épisodes 68

  1. Illia Polosukhin: "Not Your AI, Not Your Intelligence"

    57 min

    Illia Polosukhin, co-founder of NEAR Protocol and co-author of "Attention Is All You Need," on why AI is the front end and blockchain is the back end, why agents will need more than a payments rail, and why he …

  2. Zach Pandl: Why Grayscale Says It's Time to Buy Bitcoin

    55 min

    Zach Pandl, Head of Research at Grayscale, on why Grayscale gave clients the green light to buy Bitcoin, why he thinks the June low marked the bottom, and why Bitcoin rallied even after the Fed hiked and the …

  3. Chris Giancarlo: "The Real Choice Will Be Freedom or Control"

    48 min

    Chris Giancarlo, the former CFTC chairman known as CryptoDad, on why the real choice in digital money is freedom or control, why stablecoins offer no more privacy than a Chinese or European CBDC, and why he …

  4. Jeff Booth: Money Is Theft and the Debt Can't Be Repaid

    49 min

    Jeff Booth (Ego Death Capital, author of The Price of Tomorrow) on why a debt-based money system has to quietly take from you to stay solvent, why $365 trillion of global debt can never be repaid, and why only …

  5. Matt Hougan: If the AI Trade Breaks, Bitcoin Is a Generational Buy

    38 min

    Matt Hougan (Bitwise CIO) on why the most complex macro setup in 30 years still points to seven-figure Bitcoin, and what to own in crypto now that the zombie chains are dying off.In this episode of 51 Insights …

  6. Tokenizing $100T in Treasuries and equities without breaking the market, with Nadine Chakar

    36 min

    Nadine Chakar (DTCC) on why market infrastructure that safekeeps $100T+ can't afford a bad day — and what it takes to tokenize Treasuries and equities without breaking settlement.In this episode of 51 Insights …

  7. Scott Melker (Wolf of All Streets): Clarity, Robinhood, XRP, $250K Bitcoin

    47 min

    In this episode of 51 Insights, Marc Baumann speaks with Scott Melker about Bitcoin as a “liquidation sale,” why most tokens never needed to exist, zombie layer-ones, Robinhood’s chain bet, the Clarity Act, and …

  8. The Next Trillion Dollar Crypto Opportunity with Anthony B. (Coinbase Asset Management)

    43 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “The next cycle is gonna be defined by on-chain asset management and what does it mean to be a fiduciary …

  9. The $2T market still running on spreadsheets

    35 min

    Hi, it’s Marc. ✌️ “Now my balance sheet as an originator drops from a week’s worth of production to one loan’s worth of production.” Mike Manning, Head of Institutional Finance, Ava Labs That is the most useful …

  10. why a KKR partner left for DeFi (with Xiao-Xiao, President of Jupiter)

    19 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “We did over $1.2 trillion of onchain trading volume across spot and perps.” One app on Solana processed …

  11. "waiting isn't a strategy", with Christian Schmid, Global Banking Lead, BCG

    41 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “Waiting and seeing is not a strategy.” A senior partner and global banking lead at BCG just put a number …

  12. "Europe's biggest problem is Europe", with Michael Every, Global Strategist at Rabobank

    43 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “And they fail to see that sometimes the madness is actually the method.” Germany is losing about 10,000 …

  13. the $4 quadrillion switch

    59 min

    “We are done with POCs, we’re done with experiments. This is about real world assets moving on real rails to make a real difference.” - Nadine Chakar Last week, July 15, DTCC processed the first live tokenized …

  14. Most AI investors are backing the wrong layer, with Stephen Messer (Internet & AI Pioneer)

    43 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “Nobody really wants to talk about the hedge that all the buildup of data centers is.” Stephen Messer …

  15. The government seized his $110B bank, with Scott Shay (Ex Signature Bank Chairman)

    31 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “If you gave people the choice between full reserve banking and fractional banking, they’d take full …

  16. Inside JP Morgan's $3T tokenization machine, with Dennis Cristallo, Head of Wealth Management at Kinexys, JPMorgan

    36 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “Blockchain doesn’t solve all problems. It solves some problems really, really well.” JP Morgan has …

  17. Stablecoin issuance is overrated, with Tony McLaughlin, Founder & CEO at Ubyx

    44 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “I’m not a fan of stablecoins being co-opted by the cards world. I’m not a fan of cards on the front end …

  18. How stablecoins saved the dollar, with Brent Johnson, Santiago Capital

    36 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ Brent Johnson has spent roughly 25 years in financial markets, and he has one of the cleanest frameworks …

  19. Why “DeFi is dead” and what replaces it with Sidney Powell, CEO of Maple Finance

    37 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ In January 2026, Sidney Powell went on record with CoinDesk and said a high-profile on-chain credit …

  20. The $700T blueprint, with Robert Leshner, Co-Founder and CEO of Superstate

    41 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ Robert Leshner is one of the rare founders who built one of DeFi’s defining protocols, Compound, in 2017 …

  21. How the U.S. Weaponized the Dollar (And Stablecoins), with Eddie Fishman, New York Times Bestseller

    44 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ In 2025, Eddie Fishman, a former State Department and Treasury official who helped design the sanctions …

  22. the scalability trade-off is dead, with Bryan Pellegrino, CEO of LayerZero

    58 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ I watched the DTCC’s CTO go on stage and say one sentence that reframed everything I thought about …

  23. The man who co-wrote HTTP/2 just IPO'd a crypto bank, with Mike Belshe, CEO of BitGo

    46 min

    Hi, it’s Marc. ✌️ The man who co-wrote HTTP/2, the protocol loading this page right now, just IPO’d a crypto bank. Priced at $18 in January, trading at ~$10 today. And he doesn’t care. Mike Belshe started BitGo …

  24. "I apologize", SEC Commissioner Hester Peirce on Crypto's New Rules

    44 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ An SEC Commissioner just apologized to the crypto industry. On the record. To us. “The regulatory approach …

  25. He ran the NYSE, now he's putting it on a blockchain, with Michael Blaugrund, VP at ICE

    42 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ We sat down with Michael Blaugrund, the man bridging the world’s most important equity market, the NYSE …

  26. The liquidity cycle just broke bitcoin, with Michael Howell, Founder at CrossBorder Capital

    47 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ There's a chart making the rounds right now. Gold at $5,400. Bitcoin at $66,000. One is at an all-time …

  27. Why Polygon chose payments, with Marc Boiron, CEO of Polygon Labs

    1 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “The idea of general purpose blockchains or blockchains where all block space is worth the same is going …

  28. Leading economist on why Bitcoin’s biggest risk isn’t regulation, with Garrick Hileman

    55 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “Everyone has a boss. The central bank’s boss is a devil known as inflation. When inflation is tame, they …

  29. Why the application layer is crypto’s next $10T opportunity, with Richard Galvin, CIO of DACM

    43 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ "We think the space now moves to a growth phase where the underlying build-out is largely done and value …

  30. Why altcoins will be bigger than Bitcoin, with Yat Siu, Co-founder of Animoca Brands

    49 min

    This is a free preview of a paid episode. To hear more, visit 51insights.substack.com Hi, it’s Marc. ✌️ “Capitalism is the superior system broadly. But when left unchecked, it has a lot of problems. And the …

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