JAMA Clinical Reviews
- Episodes
- 508
- Released
- weekly
- Latest episode
- Nov 12, 2026
About the podcast
Author interviews that explore the latest clinical reviews.
Episodes 508
Diagnosis and Treatment of Acute Ischemic Stroke
Ischemic stroke is a leading cause of disability and death and accounts for about 85% of strokes in the US. Author Gregory Albers, MD, of Stanford University Medical Center joins JAMA Deputy Editor Karen …
Show notes
Ischemic stroke is a leading cause of disability and death and accounts for about 85% of strokes in the US. Author Gregory Albers, MD, of Stanford University Medical Center joins JAMA Deputy Editor Karen Lasser, MD, MPH, to discuss the diagnosis and treatment of ischemic stroke. Related Content:
Idiosyncratic Drug-Induced Liver Injury: Diagnosis, Risk Factors, and Management
Idiosyncratic drug-induced liver injury is damage caused by prescription or over-the-counter medications or herbal dietary supplements that is not dose-dependent. JAMA Associate Editor Beverly Forsyth, MD …
Show notes
Idiosyncratic drug-induced liver injury is damage caused by prescription or over-the-counter medications or herbal dietary supplements that is not dose-dependent. JAMA Associate Editor Beverly Forsyth, MD, speaks with author Naga Chalasani, MD, of Indiana University School of Medicine about risk factors, evaluation, and treatment of patients with idiosyncratic drug-induced liver injury. Related Content:
Diagnosis and Management of Childhood Obesity
Childhood obesity affects approximately 15% of children aged 2 to 12 and is associated with adverse health outcomes in adulthood. Author Claudia K. Fox, MD, MPH, of the University of Minnesota Medical School …
Show notes
Childhood obesity affects approximately 15% of children aged 2 to 12 and is associated with adverse health outcomes in adulthood. Author Claudia K. Fox, MD, MPH, of the University of Minnesota Medical School joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss epidemiology, diagnosis, and treatment of childhood obesity. Related Content:
Heart Transplant for Advanced Heart Failure
Heart transplant for patients with advanced heart failure can lead to improved survival and quality of life. Author JoAnne Lindenfeld, MD, of Vanderbilt University joins JAMA Associate Editor David Simel, MD …
Show notes
Heart transplant for patients with advanced heart failure can lead to improved survival and quality of life. Author JoAnne Lindenfeld, MD, of Vanderbilt University joins JAMA Associate Editor David Simel, MD, MHS, to discuss indications, transplant evaluation, management after transplant, long-term complications, and survival. Related Content:
Narcolepsy: A Review
Narcolepsy is a chronic neurologic disorder that causes severe daytime sleepiness and impaired quality of life. Author Tom Scammell, MD, of Harvard Medical School joins JAMA Deputy Editor Karen Lasser, MD, MPH …
Show notes
Narcolepsy is a chronic neurologic disorder that causes severe daytime sleepiness and impaired quality of life. Author Tom Scammell, MD, of Harvard Medical School joins JAMA Deputy Editor Karen Lasser, MD, MPH, to discuss the etiology, clinical presentation, diagnostic evaluation, and treatment of narcolepsy. Related Content:
Influenza, RSV, and COVID-19 Vaccines: Effectiveness, Safety, and Trust in 2026
Respiratory virus vaccine effectiveness and safety for influenza, RSV, and COVID-19 are reviewed, including new evidence, risks, and recommendations. JAMA Deputy Editor Preeti Malani, MD, MSJ, speaks with …
Show notes
Respiratory virus vaccine effectiveness and safety for influenza, RSV, and COVID-19 are reviewed, including new evidence, risks, and recommendations. JAMA Deputy Editor Preeti Malani, MD, MSJ, speaks with Rochelle Walensky, MD, MPH, professor of medicine at Harvard Medical School and former CDC Director, about vaccine data, public trust, and the 2026 respiratory virus season. Related Content:
Vaccines for Cancer Treatment
Cancer vaccines stimulate immune cells to recognize proteins or mutations found on or within cancer cells, facilitating destruction of cancer cells. Several vaccines are approved and others are in development …
Show notes
Cancer vaccines stimulate immune cells to recognize proteins or mutations found on or within cancer cells, facilitating destruction of cancer cells. Several vaccines are approved and others are in development for cancer treatment. Author Nora Disis, MD, JAMA Deputy Editor and Editor in Chief of JAMA Oncology, discusses cancer vaccines and more with JAMA Deputy Editor Mary McDermott, MD. Related Content:
Idiopathic Normal Pressure Hydrocephalus: Diagnosis and Treatment
Idiopathic normal pressure hydrocephalus (iNPH) affects approximately 1% to 4% of adults aged 65 years and older and is associated with gait impairment, cognitive decline, and urinary dysfunction. Author Mark …
Show notes
Idiopathic normal pressure hydrocephalus (iNPH) affects approximately 1% to 4% of adults aged 65 years and older and is associated with gait impairment, cognitive decline, and urinary dysfunction. Author Mark G. Luciano, MD, PhD, from Johns Hopkins University, discusses this and more with JAMA Deputy Editor Kristin Walter, MD, MS. Related Content:
Rheumatoid Arthritis
Rheumatoid arthritis can affect any synovial joint and cause irreversible damage, but early diagnosis and treatment with DMARDs can reduce inflammation and lower the risk of joint destruction. JAMA Associate …
Show notes
Rheumatoid arthritis can affect any synovial joint and cause irreversible damage, but early diagnosis and treatment with DMARDs can reduce inflammation and lower the risk of joint destruction. JAMA Associate Editor David Simel, MD, MHS, is joined by review coauthor Josef Smolen, MD, to discuss this topic. Related Content:
An Overview of Postural Orthostatic Tachycardia Syndrome (POTS)
POTS is a chronic autonomic disorder characterized by excessive orthostatic tachycardia and multisystem symptoms that affects an estimated 0.1% to 1% of the US population. Author Satish Raj, MD, MSCI, of …
Show notes
POTS is a chronic autonomic disorder characterized by excessive orthostatic tachycardia and multisystem symptoms that affects an estimated 0.1% to 1% of the US population. Author Satish Raj, MD, MSCI, of University of Calgary Cumming School of Medicine joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss current evidence about the pathophysiology, diagnosis, and management of POTS. Related Content:
Medication Treatments for Alcohol Use Disorder
Naltrexone, acamprosate, disulfiram, and topiramate are effective but underused medications for treatment of alcohol use disorder. Author Stephen Holt, MD, MS, of Yale School of Medicine joins JAMA Deputy …
Show notes
Naltrexone, acamprosate, disulfiram, and topiramate are effective but underused medications for treatment of alcohol use disorder. Author Stephen Holt, MD, MS, of Yale School of Medicine joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss first-line pharmacotherapy for alcohol use disorder and important safety, efficacy, and hospital initiation considerations. Related Content:
Liquid Biopsy Tests for Cancer
Circulating tumor DNA (ctDNA)(liquid biopsies) can help monitor cancer progression, detect residual cancer after treatment, and identify genetic changes within cancer cells that could affect treatment response …
Show notes
Circulating tumor DNA (ctDNA)(liquid biopsies) can help monitor cancer progression, detect residual cancer after treatment, and identify genetic changes within cancer cells that could affect treatment response. Author Ben Ho Park, MD, PhD, of the Vanderbilt-Ingram Cancer Center discusses current evidence regarding use of liquid biopsies in management of cancer with JAMA Deputy Editor Mary McGrae McDermott, MD. Related Content:
Patient-Clinician Communication About Physical Activity
Physical activity is an effective component of care for people with chronic medical conditions. In this podcast, JAMA Insights author Alessio Bricca, PhD, University of Southern Denmark, discusses adaptable …
Show notes
Physical activity is an effective component of care for people with chronic medical conditions. In this podcast, JAMA Insights author Alessio Bricca, PhD, University of Southern Denmark, discusses adaptable methods to promote physical activity in patients with chronic medical conditions with host Anne Rentoumis Cappola, MD, ScM. Related Content:
Classic Hodgkin Lymphoma
Hodgkin lymphoma is a relatively rare disease, with approximately 82 409 incident cases reported globally in 2022, and 8720 cases reported in the US in 2025. Author Alison Moskowitz, MD, of Memorial Sloan …
Show notes
Hodgkin lymphoma is a relatively rare disease, with approximately 82 409 incident cases reported globally in 2022, and 8720 cases reported in the US in 2025. Author Alison Moskowitz, MD, of Memorial Sloan Kettering Cancer Center joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss current evidence about the diagnosis and management of Hodgkin lymphoma in adults. Related Content:
The Sleep-Weight Connection
Suboptimal sleep quality and quantity are associated with higher body mass index and more difficulty losing weight. In this podcast, JAMA Insights author Atul Malhotra, MD, from the University of California …
Show notes
Suboptimal sleep quality and quantity are associated with higher body mass index and more difficulty losing weight. In this podcast, JAMA Insights author Atul Malhotra, MD, from the University of California, San Diego, discusses evidence regarding sleep and obesity with JAMA Deputy Editor Mary McDermott, MD. Related Content:
Management of Dyslipidemia
Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of global mortality and is strongly associated with cumulative exposure to atherogenic lipoproteins across the lifespan. Author Amber E …
Show notes
Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of global mortality and is strongly associated with cumulative exposure to atherogenic lipoproteins across the lifespan. Author Amber E. Johnson, MD, MS, MBA, of the University of Chicago joins JAMA Senior Editor Philip Greenland, MD, to discuss the ACC/AHA guideline on management of dyslipidemia. Related Content:
Hip Fractures: Management and Prevention
Hip fractures are a leading cause of disability and death in older adults. This episode summarizes risk factors, prevention, and medical and surgical management of hip fractures. JAMA Deputy Editor Mary M …
Show notes
Hip fractures are a leading cause of disability and death in older adults. This episode summarizes risk factors, prevention, and medical and surgical management of hip fractures. JAMA Deputy Editor Mary M. McDermott, MD, interviews Douglas Kiel, MD, MPH, of Harvard Medical School and Marcus Institute for Aging Research. Related Content:
Alcohol-Related Liver Disease
Alcohol-related liver disease is the leading cause of liver-related morbidity and mortality and the most common indication for liver transplant in Europe and the US. Author Aleksander Krag, MD, PhD, of the …
Show notes
Alcohol-related liver disease is the leading cause of liver-related morbidity and mortality and the most common indication for liver transplant in Europe and the US. Author Aleksander Krag, MD, PhD, of the University of Southern Denmark joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss a recent review on this topic published in JAMA. Related Content:
An Overview of Familial Hypercholesterolemia
Worldwide, heterozygous familial hypercholesterolemia (FH) affects approximately 1 in 250 to 350 individuals. Author James Stein, MD, of the University of Wisconsin School of Medicine and Public Health joins …
Show notes
Worldwide, heterozygous familial hypercholesterolemia (FH) affects approximately 1 in 250 to 350 individuals. Author James Stein, MD, of the University of Wisconsin School of Medicine and Public Health joins JAMA Deputy Editor Karen Lasser, MD, MPH, to discuss the epidemiology, diagnosis, and treatment of both homozygous and heterozygous FH. Related Content:Transforming Communication Between Patients and Clinicians
Patient portal messaging continues to expand across health systems, and it has become an increasingly important method for patient-clinician communication. Authors Michal Mankowski, PhD, assistant professor …
Show notes
Patient portal messaging continues to expand across health systems, and it has become an increasingly important method for patient-clinician communication. Authors Michal Mankowski, PhD, assistant professor, and Jane Long, MD, research resident, both from the Department of Surgery at NYU, discuss their new research letter with JAMA Deputy Editor Joseph Ross, MD, MHS. Related Content:
Low Back Pain: Diagnosis and Treatment
Nonspecific low back pain is a leading cause of disability, with most cases lacking a clear anatomic cause. This episode reviews risk factors, diagnosis, and current evidence-based treatments for acute and …
Show notes
Nonspecific low back pain is a leading cause of disability, with most cases lacking a clear anatomic cause. This episode reviews risk factors, diagnosis, and current evidence-based treatments for acute and chronic low back pain. JAMA Deputy Editor Mary M. McDermott, MD, interviews author James McAuley, PhD, of the University of New South Wales. Related Content:
Survivors of Cyanotic Congenital Heart Disease
Cyanotic congenital heart diseases occur in approximately 0.2% of live births in the US, but survival to adulthood is common with current surgical interventions. JAMA Associate Editor David Simel, MD, MHS …
Show notes
Cyanotic congenital heart diseases occur in approximately 0.2% of live births in the US, but survival to adulthood is common with current surgical interventions. JAMA Associate Editor David Simel, MD, MHS, speaks with author Michael Landzberg, MD, who coauthored a recent review in JAMA on this topic. Related Content:
Point-of-Care Ultrasound for the Diagnosis of Pneumonia: A Review
Community-acquired pneumonia (CAP) accounts for 1.4 million emergency department visits and 740 000 hospitalizations annually in the US. Author Andre Kumar, MD, MEd, of Stanford University School of Medicine …
Show notes
Community-acquired pneumonia (CAP) accounts for 1.4 million emergency department visits and 740 000 hospitalizations annually in the US. Author Andre Kumar, MD, MEd, of Stanford University School of Medicine joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the use of point-of-care ultrasound for diagnosis of CAP. Related Content:
Cesarean Delivery on Request
Cesarean delivery on maternal request requires individualized counseling. Reduced risks of pelvic floor disorders should be weighed against surgical risks and future risks including abnormal placentation …
Show notes
Cesarean delivery on maternal request requires individualized counseling. Reduced risks of pelvic floor disorders should be weighed against surgical risks and future risks including abnormal placentation. Author Marianna Alperin, MD, MS, from UC San Diego School of Medicine, discusses this and more with JAMA Deputy Editor Linda Brubaker, MD. Related Content:
Diet and Exercise Recommendations for Patients Taking GLP-1 Receptor Agonists
The GLP-1 receptor agonists reduce appetite and greatly facilitate weight loss. Robert Kushner, MD, of Northwestern University Feinberg School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to …
Show notes
The GLP-1 receptor agonists reduce appetite and greatly facilitate weight loss. Robert Kushner, MD, of Northwestern University Feinberg School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss appropriate diet and exercise recommendations for patients receiving GLP-1 receptor agonists for weight loss. Related Content:
An Overview of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS), which affects about 25 000 individuals in the US, causes progressive weakness but has varied presentations. Several FDA-approved medications are now available for ALS …
Show notes
Amyotrophic lateral sclerosis (ALS), which affects about 25 000 individuals in the US, causes progressive weakness but has varied presentations. Several FDA-approved medications are now available for ALS. Author John Ravits, MD, of UC San Diego School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of ALS. Related Content:
Hepatitis B: Global Insights on Transmission and Treatment
Hepatitis B virus (HBV) infection affects around 254 million people worldwide and causes more than 1 million deaths annually. Author Anna Lok, MD, from the University of Michigan discusses HBV transmission …
Show notes
Hepatitis B virus (HBV) infection affects around 254 million people worldwide and causes more than 1 million deaths annually. Author Anna Lok, MD, from the University of Michigan discusses HBV transmission, screening, and treatment with JAMA Associate Editor Beverly Forsyth, MD. Related Content:
Review of Cardiac Resynchronization Therapy
Heart failure (HF) affects more than 64 million individuals worldwide, and 20% to 30% of patients with HF and systolic dysfunction have cardiac dyssynchrony due to conduction system disease. JAMA Review author …
Show notes
Heart failure (HF) affects more than 64 million individuals worldwide, and 20% to 30% of patients with HF and systolic dysfunction have cardiac dyssynchrony due to conduction system disease. JAMA Review author Mihail Chelu, MD, PhD, of Baylor College of Medicine discusses cardiac resynchronization therapy with JAMA Associate Editor David Simel, MD, MHS. Related Content:
Prepregnancy Care and Counseling to Improve Maternal and Neonatal Outcomes
In the US, approximately 66% of reproductive-aged women have at least 1 modifiable risk factor for adverse pregnancy outcomes. Authors and ob-gyns Kylie Cooper, MD, and Daniel Breitkopf, MD, both from the Mayo …
Show notes
In the US, approximately 66% of reproductive-aged women have at least 1 modifiable risk factor for adverse pregnancy outcomes. Authors and ob-gyns Kylie Cooper, MD, and Daniel Breitkopf, MD, both from the Mayo Clinic, discuss ways to reduce maternal morbidity and mortality and improve neonatal outcomes with JAMA Senior Editor Karen Lasser, MD, MPH. Related Content:
Diagnosis and Management of Endometrial Cancer
Endometrial cancer accounts for 95% of uterine cancers, which are the fourth most common cancer in women in the US. Author Karen McLean, MD, PhD, of Roswell Park Comprehensive Cancer Center joins JAMA Senior …
Show notes
Endometrial cancer accounts for 95% of uterine cancers, which are the fourth most common cancer in women in the US. Author Karen McLean, MD, PhD, of Roswell Park Comprehensive Cancer Center joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence about diagnosis and treatment of endometrial cancer. Related Content:
These are the latest 40 of 508 episodes. You’ll find older episodes in the podcast’s feed.
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