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JAMA Clinical Reviews

Rheumatoid Arthritis

September 10, 2026 · 23 min

Show notes

Rheumatoid arthritis can affect any synovial joint and cause irreversible damage, but early diagnosis and treatment with DMARDs can reduce inflammation and lower the risk of joint destruction. JAMA Associate Editor David Simel, MD, MHS, is joined by review coauthor Josef Smolen, MD, to discuss this topic. Related Content:

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